Antioxidation medicine

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Infectious Medicine

Keywords

  • Oxidation, antioxidation, inflammatory diseases, alpha-1-microglobulin

Research

Antioxidation medicine describes how the body is protected against unwanted oxidation. ’Oxidation’ is a name for the chemical reactions between oxygen and the molecules of the body. Protection molecules, ’antioxidants’ are produced by the body to prevent the oxidation reactions from becoming violent. Without antioxidation control our bodies would quickly decay similar to a log fire or a decomposing apple. Antioxidants are also essential to protect bystander tissues during inflammatory diseases, and ensure that humans can stay healthy during a life-span of more than 70 years. Perhaps the most important human antioxidant is called alpha-1-microglobulin (A1M). Our research is focussed on A1M. We are studying structure and functions of this protein and also trying to develop disease treatments by using A1M. Together with clinical researchers and industry we are now working with preeclampsia, brain damage, kidney damage, radiation cancer therapy, retinal detachment and atherosclerosis.

Recent research outputs

Alex Adusei Agyemang, Kristbjörg Sveinsdóttir, Suvi Vallius, SVEINSDOTTIR, S. N. J. O. L. A. U. G., Matteo Bruschettini, Romantsik, O., Hellström, A., Smith, L. E. H., Ohlsson, L., Holmqvist, B., Magnus Gram & David Ley 2017 Jun 10 In : Translational Stroke Research. p. 1-13 13 p.

Research output: Contribution to journalArticle

Naudin, C., Schumski, A., Salo-Ahen, O. M. H., Heiko Herwald & Emanuel Smeds 2017 Feb 7 In : Microbial Biotechnology.

Research output: Contribution to journalArticle

Bo Åkerström, CEDERLUND, M. A. R. T. I. N., Jesper Bergwik, Oscar Manouchehrian, Arnér, K., Holmgren Taylor, I., Fredrik Ghosh & Linnéa Taylor 2017 In : Current Eye Research. 42, 6, p. 948-961

Research output: Contribution to journalArticle

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