Biomimetic Retinal Tissue Engineering

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Ophthalmology

Research

Traditionally, experimental neuronal research is conducted on single cells after disruption of the tissue. A more pertinent approach to the complex CNS is to consider cells, extracellular matrix, and cell junctions as a tissue continuum through which mechanical and biochemical information is bidirectionally communicated. Our research is focused on retinal cell interactions in health and disease, and how these interactions can be modified by tissue engineering. We believe that perturbation of the tissue continuum is a common mechanism behind retinal degenerative disease, and we are currently exploring this hypothesis in a project called Retinal Biomechanics. In addition, we are investigating treatment related aspects in projects involving Synthetic Vitreous Substitution and Retinal Transplantation. To summarize, our research delineates tissue engineering projects in a wide translational spectrum aiming to understand and develop new treatments for blinding retinal disease.

Recent research outputs

Bo Åkerström, CEDERLUND, M. A. R. T. I. N., Jesper Bergwik, Oscar Manouchehrian, Arnér, K., Holmgren Taylor, I., Fredrik Ghosh & Linnéa Taylor 2017 In : Current Eye Research. 42, 6, p. 948-961

Research output: Contribution to journalArticle

Anna Cardiakidis Myers, Kjellström, S., Bruun, A., Isaksson, B., Fredrik Ghosh, Sten Andréasson & Ponjavic, V. 2009 Jan In : Retina. 29, 1, p. 106-111 6 p.

Research output: Contribution to journalArticle

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