Cell Pathology, Malmö

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology
  • Immunology in the medical area

Keywords

  • Inflammation, leukotrienes, colon cancer

Description

In this group we study the tumor microenvironment in the context of colon cancer and with a focus on the inflammatory mediators leukotriene D4 (LTD4) and prostaglandins (PGE2) and their respective receptors. These mediators and their receptors are enriched in colon cancer cells and colon cancer tissues, which demonstrate there, contribute to tumor development and progression. Several of the observations and ideas are generated from our analyses of human colon cancer materials. Our aim is to generate solid support for novel and complementary treatments of colon cancer patients that focus on the inflammatory component of the tumor microenvironment.

Recent research outputs

Janina Osman, Savari, S., Chandrashekar, N. K., Bellamkonda, K., Douglas, D. & Anita Sjölander 2017 May 23 In : Oncotarget. 8, 21, p. 34773-34786 14 p.

Research output: Contribution to journalArticle

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