Clinical pathology, Malmö

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology
  • Cell and Molecular Biology

Keywords

  • Kidney cancer

Description

We mainly study two important aspects of human kidney disease. First, we study the cellular background for kidney regeneration. The traditional concept that the human kidney lacks a stem cell compartment has recently been challenged by an alternative view, stating that stem cells indeed are localized to the kidney. The issue is thus far from settled and we are currently researching this important area. We have discovered important markers and signaling networks, that characterize the regenerative cells of the human kidney and are currently following up these leads. Our second area of investigation concerns renal cell carcinoma. The various forms of kidney cancer all display a very aberrant cellular metabolism. We currently investigate the metabolism of clear cell renal cell carcinoma (CCRCC). The goal is to exploit the pseudohypoxic cellular metabolism of this malignancy to identify novel therapeutic targets. Finally, papillary renal cell carcinoma, is also a focus for our research.

Research

Recent research outputs

Lindström, L., Li, T., Malycheva, D., Kancharla, A., Helén Nilsson, Neelanjan Vishnu, Hindrik Mulder, Martin Johansson, Rosselló, C. A. & Maria Alvarado-Kristensson, 2018 May 3, In : Communications Biology. 1, https://doi.org/10.1038/s42003-018-0037-3, 37

Research output: Contribution to journalArticle

Krzysztof M. Krawczyk, Matak, D., Szymanski, L., Szczylik, C., Porta, C. & Czarnecka, A. M., 2018 Feb 17, In : Cytotechnology. 22 p.

Research output: Contribution to journalArticle

Krzysztof Krawczyk, 2018, Lund: Lund University, Faculty of Medicine. 84 p.

Research output: ThesisDoctoral Thesis (compilation)

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