Diabetes and Endocrinology

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Endocrinology and Diabetes
  • Cardiac and Cardiovascular Systems

Keywords

  • Type 2 diabetes

Description

Understanding the genetic and metabolic complexity of diabetes could help in identifying novel drug targets. A new classification of diabetes may pave the way for early intensified treatment and thereby possibly prevent late diabetic complications ascribed to the “metabolic memory”. It may also help the pharma industry to better stratify patients for drug trials and thereby reduce cost for development of new drugs. Dissect the genetic and metabolic complexity of diabetes and provide a refined diabetes classification that can pave the way for precision medicine in diabetes and development of a decision tool (road map) for the diabetic patients.

Recent research outputs

Sharma, A., Halu, A., Decano, J. L., Padi, M., Liu, Y., Rashmi B. Prasad, Fadista, J., Santolini, M., Menche, J., Weiss, S. T., Vidal, M., Silverman, E. K., Aikawa, M., Barabási, A., Leif Groop & Loscalzo, J. 2018 Dec 1 In : npj Systems Biology and Applications. 4, 1

Research output: Contribution to journalArticle

Ström, K. , Morales-Alamo, D. , Ottosson, F. , Edlund, A. , Hjort, L. , Jörgensen, S. W. , Almgren, P. , Zhou, Y. , Martin-Rincon, M. , Ekman, C. , Pérez-López, A. , Ekström, O. , Perez-Suarez, I. , Mattiasson, M. , De Pablos-Velasco, P. , Oskolkov, N. , Ahlqvist, E. , Wierup, N. , Eliasson, L. , Vaag, A. & 6 others Leif Groop, Karin G. Stenkula, Céline Fernandez, Calbet, J. A. L., Holmberg, H. C. & Ola Hansson 2018 Dec 1 In : Scientific Reports. 8, 1, 3016

Research output: Contribution to journalArticle

Gusarova, V. , O'Dushlaine, C. , Teslovich, T. M. , Benotti, P. N. , Mirshahi, T. , Gottesman, O. , Van Hout, C. V. , Murray, M. F. , Mahajan, A. , Nielsen, J. B. , Fritsche, L. , Wulff, A. B. , Gudbjartsson, D. F. , Sjögren, M. , Emdin, C. A. , Scott, R. A. , Lee, W-J. , Small, A. , Kwee, L. C. , Dwivedi, O. P. & 61 others Rashmi B Prasad, Bruse, S., Lopez, A. E., Penn, J., Marcketta, A., Leader, J. B., Still, C. D., Kirchner, H. L., Mirshahi, U. L., Wardeh, A. H., Hartle, C. M., Habegger, L., Fetterolf, S. N., Tusie-Luna, T., Morris, A. P., Holm, H., Steinthorsdottir, V., Sulem, P., Thorsteinsdottir, U., Rotter, J. I., Chuang, L-M., Damrauer, S., Birtwell, D., Brummett, C. M., Khera, A. V., Natarajan, P., Marju Orho-Melander, Flannick, J., Lotta, L. A., Willer, C. J., Holmen, O. L., Ritchie, M. D., Ledbetter, D. H., Murphy, A. J., Borecki, I. B., Reid, J. G., Overton, J. D., Ola Hansson, Leif Groop, Shah, S., Kraus, W. E., Rader, D. J., Ida Chen, Y-D., Hveem, K., Wareham, N. J., Kathiresan, S., Olle Melander, Stefansson, K., Nordestgaard, B. G., Tybjaerg-Hansen, A., Abecasis, G. R., Altshuler, D., Florez, J. C., Boehnke, M., McCarthy, M., Yancopoulos, G. D., Carey, D. J., Shuldiner, A. R., Baras, A., Dewey, F. E. & Gromada, J. 2018 Jun 13 In : Nature Communications. 9, p. 1-11 2252

Research output: Contribution to journalArticle

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