Experimental Infection Medicine, Malmö

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Microbiology in the medical area
  • Immunology in the medical area
  • Cell and Molecular Biology

Keywords

  • Bacteria, biofilms, HAMLET

Description

Our laboratory is focused on understanding host-pathogen interactions, with emphasis on respiratory pathogens, and to use this knowledge to develop novel preventive and therapeutic strategies to protect against bacterial infection. Our work focuses on both the factors used by bacteria to establish colonization and cause disease and how this is counteracted by host factors in human milk and by the host inflammatory response to colonization and infection. The main research projects in the laboratory are: 1) The study of biofilm formation during bacterial colonization. 2) Applying the information from our pathogenesis studies to develop novel treatment strategies. 3) Studying the direct bactericidal activity and the antibiotic-seistizing activity of a human milk protein-lipid complex (HAMLET, human alpha-lactalbumin made lethal to tumor cells).

Recent research outputs

Pettigrew, M. M., Alderson, M. R., Bakaletz, L. O., Barenkamp, S. J., Anders P. Hakansson, Mason, K. M., Nokso-Koivisto, J., Patel, J. A., Pelton, S. I. & Murphy, T. F. 2017 Apr 1 In : Otolaryngology - Head and Neck Surgery. 156, 4_suppl, p. S76-S87

Research output: Contribution to journalArticle

Yashuan Chao, Caroline Bergenfelz & Anders P. Håkansson 2017 Methods in Molecular Biology. Humana Press, Vol. 1535, p. 285-299 15 p. (Methods in Molecular Biology; vol. 1535)

Research output: Chapter in Book/Report/Conference proceedingBook chapter

Camilla Rydberg Millrud, Caroline Bergenfelz & Karin Leandersson 2017 In : Oncotarget. 8, 2, p. 3649-3665 17 p.

Research output: Contribution to journalReview article

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