Histopathological diagnostics in lung cancer

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology


Most cancers are diagnosed using a microscope. Lung cancer may be tricky to diagnose as there is often limited tissue to examine from the tumor sampling. Different types of lung cancer are treated differently, and may have different prognosis. Also, metastases from other organs to the lungs are very common and are handled differently. Thus, it is important with correct diagnosis. Immunohistochemistry is often necessary for subtyping and determination of origin of the tumor. Molecular profiling, normally used for treatment prediction, may sometimes also be used just to get the right diagnosis. The aim of my research is to improve the diagnostic procedure, but also extends to classification and pathological/surgical issues etc. The main focus is immunohistochemical staining and molecular profiling in diagnostics of tumors in the lung.

Recent research outputs

Brunnström, H. , Manjer, J. , Melander, O. & 138 others McKay, J. D., Hung, R. J., Han, Y., Zong, X., Carreras-Torres, R., Christiani, D. C., Caporaso, N. E., Johansson, M., Xiao, X., Li, Y., Byun, J., Dunning, A., Pooley, K. A., Qian, D. C., Ji, X., Liu, G., Timofeeva, M. N., Bojesen, S. E., Wu, X., Le Marchand, L., Albanes, D., Bickeböller, H., Aldrich, M. C., Bush, W. S., Tardon, A., Rennert, G., Teare, M. D., Field, J. K., Kiemeney, L. A., Lazarus, P., Haugen, A., Lam, S., Schabath, M. B., Andrew, A. S., Shen, H., Hong, Y-C., Yuan, J-M., Bertazzi, P. A., Pesatori, A. C., Ye, Y., Diao, N., Su, L., Zhang, R., Brhane, Y., Leighl, N., Johansen, J. S., Mellemgaard, A., Saliba, W., Haiman, C. A., Wilkens, L. R., Fernandez-Somoano, A., Fernandez-Tardon, G., van der Heijden, H. F. M., Kim, J. H., Dai, J., Hu, Z., Davies, M. P. A., Marcus, M. W., Muller, D. C., Overvad, K., Trichopoulou, A., Tumino, R., Doherty, J. A., Barnett, M. P., Chen, C., Goodman, G. E., Cox, A., Taylor, F., Woll, P., Brüske, I., Wichmann, H-E., Manz, J., Muley, T. R., Risch, A., Rosenberger, A., Grankvist, K., Johansson, M., Shepherd, F. A., Tsao, M-S., Arnold, S. M., Haura, E. B., Bolca, C., Holcatova, I., Janout, V., Kontic, M., Lissowska, J., Mukeria, A., Ognjanovic, S., Orlowski, T. M., Scelo, G., Swiatkowska, B., Zaridze, D., Bakke, P., Skaug, V., Zienolddiny, S., Duell, E. J., Butler, L. M., Koh, W-P., Gao, Y-T., Houlston, R. S., McLaughlin, J. R., Stevens, V. L., Joubert, P., Lamontagne, M., Nickle, D. C., Obeidat, M., Timens, W., Zhu, B., Song, L., Kachuri, L., Artigas, M. S., Tobin, M. D., Wain, L. V., Rafnar, T., Thorgeirsson, T. E., Reginsson, G. W., Stefansson, K., Hancock, D. B., Bierut, L. J., Spitz, M. R., Gaddis, N. C., Lutz, S. M., Gu, F., Johnson, E. O., Kamal, A., Pikielny, C., Zhu, D., Lindströem, S., Jiang, X., Tyndale, R. F., Chenevix-Trench, G., Beesley, J., Bossé, Y., Chanock, S., Brennan, P., Landi, M. T., Amos, C. I. & SpiroMeta Consortium 2017 Jul In : Nature Genetics. 49, 7, p. 1126-1132 7 p.

Research output: Contribution to journalLetter

Grinberg, M., Djureinovic, D., Hans RR Brunnström, Mattsson, J. S., Edlund, K., Hengstler, J. G., La Fleur, L., Ekman, S., Koyi, H., Branden, E., Ståhle, E., Karin Jirström, Tracy, D. K., Pontén, F., Botling, J., Rahnenführer, J. & Micke, P. 2017 Jul In : Modern Pathology. 30, 7, p. 964-977 14 p.

Research output: Contribution to journalArticle

Hans Brunnström, Anna Johansson, Westbom-Fremer, S., Backman, M., Djureinovic, D., Patthey, A., Isaksson-Mettävainio, M., Gulyas, M. & Micke, P. 2017 Jun 30 In : Modern Pathology.

Research output: Contribution to journalArticle

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