Histopathological diagnostics in lung cancer

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology


Most cancers are diagnosed using a microscope. Lung cancer may be tricky to diagnose as there is often limited tissue to examine from the tumor sampling. Different types of lung cancer are treated differently, and may have different prognosis. Also, metastases from other organs to the lungs are very common and are handled differently. Thus, it is important with correct diagnosis. Immunohistochemistry is often necessary for subtyping and determination of origin of the tumor. Molecular profiling, normally used for treatment prediction, may sometimes also be used just to get the right diagnosis. The aim of my research is to improve the diagnostic procedure, but also extends to classification and pathological/surgical issues etc. The main focus is immunohistochemical staining and molecular profiling in diagnostics of tumors in the lung.

Recent research outputs

Hans Brunnström, Anna Johansson, Westbom-Fremer, S., Backman, M., Djureinovic, D., Patthey, A., Isaksson-Mettävainio, M., Gulyas, M. & Micke, P. 2017 Oct In : Modern Pathology. 30, 10, p. 1411-1421

Research output: Contribution to journalArticle

McKay, J. D. , Hung, R. J. , Han, Y. , Zong, X. , Carreras-Torres, R. , Christiani, D. C. , Caporaso, N. E. , Johansson, M. , Xiao, X. , Li, Y. , Byun, J. , Dunning, A. , Pooley, K. A. , Qian, D. C. , Ji, X. , Liu, G. , Timofeeva, M. N. , Bojesen, S. E. , Wu, X. , Le Marchand, L. & 121 others Albanes, D., Bickeböller, H., Aldrich, M. C., Bush, W. S., Tardon, A., Rennert, G., Teare, M. D., Field, J. K., Kiemeney, L. A., Lazarus, P., Haugen, A., Lam, S., Schabath, M. B., Andrew, A. S., Shen, H., Hong, Y-C., Yuan, J-M., Bertazzi, P. A., Pesatori, A. C., Ye, Y., Diao, N., Su, L., Zhang, R., Brhane, Y., Leighl, N., Johansen, J. S., Mellemgaard, A., Saliba, W., Haiman, C. A., Wilkens, L. R., Fernandez-Somoano, A., Fernandez-Tardon, G., van der Heijden, H. F. M., Kim, J. H., Dai, J., Hu, Z., Davies, M. P. A., Marcus, M. W., Hans Brunnström, Jonas Manjer, Olle Melander, Muller, D. C., Overvad, K., Trichopoulou, A., Tumino, R., Doherty, J. A., Barnett, M. P., Chen, C., Goodman, G. E., Cox, A., Taylor, F., Woll, P., Brüske, I., Wichmann, H-E., Manz, J., Muley, T. R., Risch, A., Rosenberger, A., Grankvist, K., Johansson, M., Shepherd, F. A., Tsao, M-S., Arnold, S. M., Haura, E. B., Bolca, C., Holcatova, I., Janout, V., Kontic, M., Lissowska, J., Mukeria, A., Ognjanovic, S., Orlowski, T. M., Scelo, G., Swiatkowska, B., Zaridze, D., Bakke, P., Skaug, V., Zienolddiny, S., Duell, E. J., Butler, L. M., Koh, W-P., Gao, Y-T., Houlston, R. S., McLaughlin, J. R., Stevens, V. L., Joubert, P., Lamontagne, M., Nickle, D. C., Obeidat, M., Timens, W., Zhu, B., Song, L., Kachuri, L., Artigas, M. S., Tobin, M. D., Wain, L. V., Rafnar, T., Thorgeirsson, T. E., Reginsson, G. W., Stefansson, K., Hancock, D. B., Bierut, L. J., Spitz, M. R., Gaddis, N. C., Lutz, S. M., Gu, F., Johnson, E. O., Kamal, A., Pikielny, C., Zhu, D., Lindströem, S., Jiang, X., Tyndale, R. F., Chenevix-Trench, G., Beesley, J., Bossé, Y., Chanock, S., Brennan, P., Landi, M. T., Amos, C. I. & SpiroMeta Consortium 2017 Jul In : Nature Genetics. 49, 7, p. 1126-1132 7 p.

Research output: Contribution to journalLetter

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