Host parasite interactions

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Infectious Medicine

Research

Severe infectious diseases, including sepsis, remain a serious medical challenge worldwide. Clinical symptoms of patients suffering from sepsis are a culmination of complex interactions between the infecting microorganism and host immune responses, such as the induction of overwhelming inflammatory reactions, systemic activation of the coagulation system, and impaired fibrinolysis. My projects are focused on so-called “host effector systems”, since evidence has accumulated that complications from an infection are caused by an over-stimulation of host defense systems that are modulated by bacteria or bacterial products. In severe infections, such as sepsis and septic shock, vascular leakage, increased cytokine levels, and coagulation/fibrinolysis dysfunction are often observed. To accomplish these tasks various in vitro, ex vivo, and in vivo models will be employed.

Recent research outputs

Halldorsdottir, H. D., Eriksson, J., Persson, B. P., H. Herwald, Lindbom, L., Weitzberg, E. & Oldner, A. 2018 Mar 22 In : Acta Anaesthesiologica Scandinavica.

Research output: Contribution to journalArticle

Westman, J., Chakrakodi, B., Snäll, J., Mörgelin, M., Madsen, M. B., Hyldegaard, O., Neumann, A., Inga Maria Frick, Norrby-Teglund, A., Lars Björck & Heiko Herwald 2018 Feb 22 In : Frontiers in Immunology. 9, FEB, p. 1-14 236

Research output: Contribution to journalArticle

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