Immunomodulatory effects of platelets during inflammation and infection
Organisational unit: Research group
Bacteria that breach the bloodstream can cause invasive infectious disease, such as sepsis and septic shock. Platelets are abundant circulating cells with a primary role in blood coagulation. The aim of my research is to elucidate the role of platelets during the pathophysiological response to inflammation and bacterial infection. Projects within the group are focussed on molecular characterisation of platelet activation in response to bacterial pathogens, and the functional consequences for the immune response; leukocytes, endothelial cells and the complement system. The knowledge generated will identify novel targets for diagnosis, prognosis and treatment of these severe manifestations of infectious disease.
Recent research outputs
Oonagh Shannon 2016 Sep 1 In : PLoS ONE. 11, 9, e0163531
Research output: Contribution to journal › Article
View All (10)