Lund OsteoArthritis Division - Molecular imaging of joint cartilage using dGEMRIC
Organisational unit: Research group
Research areas and keywords
UKÄ subject classification
Hip dysplasia, underdevelopment of the hip joint, can be present at birth but is often not diagnosed until later in life. Slipped Capital Femoral Epiphysis (SCFE) is a disease that affects teenagers and results in various degrees of deformity of the proximal femur. Both diseases are associated with hip osteoarthritis (OA) later in life, although little is known about the causality. In order to establish such relationships and to detect early signs of OA, we employ Delayed Gadolinium-Enhanced MRI of Cartilage (dGEMRIC), which is a non-invasive technique to study joint cartilage quality. We have developed dGEMRIC since the late 1990s to examine the hip and the knee. Our research aims to establish the long term effects on hip function and cartilage quality, and hence the risk of OA development, in patients with childhood hip dysplasia and SCFE. We also investigate the risk of developing OA in young adult patients with previous knee injury, using dGEMRIC and radiography.
Recent research outputs
Delayed Gadolinium-Enhanced MRI of Menisci and Cartilage (dGEMRIM/dGEMRIC) in Obese Patients With Knee Osteoarthritis: Cross-Sectional Study of 85 Obese Patients With Intra-articular Administered Gadolinium ContrastHangaard, S., Gudbergsen, H., Daugaard, C. L., Bliddal, H., Nybing, J. D., Nieminen, M. T., Casula, V., Carl Johan Tiderius & Boesen, M., 2018 Aug 13, In : Journal of Magnetic Resonance Imaging.
Research output: Contribution to journal › Article
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