Mitochondrial Medicine

Organisational unit: Research group

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  1. 2017
  2. Respiratory chain complex III deficiency due to mutated BCS1L: A novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model

    Tegelberg, S., Tomašić, N., Kallijärvi, J., Purhonen, J., Eskil Elmér, Lindberg, E., David Gisselsson Nord, Soller, M., Lesko, N., Wedell, A., Bruhn, H., Freyer, C., Stranneheim, H., Wibom, R., Nennesmo, I., Wredenberg, A., Erik A. Eklund & Vineta Fellman 2017 Apr 20 In : Orphanet Journal of Rare Diseases. 12, 1, 73

    Research output: Contribution to journalArticle

  3. Co segregation of the m.1555A>G mutation in the MT-RNR1 gene and mutations in MT-ATP6 gene in a family with dilated mitochondrial cardiomyopathy and hearing loss: A whole mitochondrial genome screening

    Alila-Fersi, O., Imen Chamkha, Majdoub, I., Gargouri, L., Mkaouar-Rebai, E., Tabebi, M., Tlili, A., Keskes, L., Mahfoudh, A. & Fakhfakh, F. 2017 Feb 26 In : Biochemical and Biophysical Research Communications. 484, 1, p. 71-78 8 p.

    Research output: Contribution to journalArticle

  4. Hospitalizations for mitochondrial disease across the lifespan in the U.S

    McCormack, S. E., Xiao, R., Kilbaugh, T. J., Michael Karlsson, Ganetzky, R. D., Cunningham, Z. Z., Goldstein, A., Falk, M. J. & Damrauer, S. M. 2017 Feb 1 In : Molecular Genetics and Metabolism.

    Research output: Contribution to journalArticle

  5. Mitochondrial dysfunction and metabolic intervention

    Johannes Ehinger 2017 Lund: Lund University, Faculty of Medicine. 75 p.

    Research output: ThesisDoctoral Thesis (compilation)

  6. 2016
  7. Cell-permeable succinate prodrugs bypass mitochondrial complex i deficiency

    Johannes K. Ehinger, Sarah Piel, Ford, R., Michael Karlsson, Fredrik Sjövall, Eleonor Åsander Frostner, Morota, S., Taylor, R. W., Turnbull, D. M., Cornell, C., Moss, S. J., Metzsch, C., Magnus J. Hansson, Fliri, H. & Eskil Elmér 2016 Aug 9 In : Nature Communications. 7, 12317

    Research output: Contribution to journalArticle

  8. White adipose tissue browning in the R6/2 mouse model of Huntington's disease

    McCourt, A. C., Jakobsson, L., Larsson, S., Cecilia Holm, Sarah Piel, Eskil Elmér & Maria Björkqvist 2016 Aug 1 In : PLoS ONE. 11, 8, e0159870

    Research output: Contribution to journalArticle

  9. Diverse and Tissue Specific Mitochondrial Respiratory Response in A Mouse Model of Sepsis-Induced Multiple Organ Failure.

    Michael Karlsson, Hara, N., Morata, S., Fredrik Sjövall, Kilbaugh, T., Magnus Hansson, Uchino, H. & Eskil Elmer 2016 In : Shock. 45, 4, p. 404-410

    Research output: Contribution to journalArticle

  10. 2015
  11. Molecular mechanisms of brain ischemia and its protection

    Uchino, H., Chijiiwa, M., Ogihara, Y. & Eskil Elmer 2015 Aug 7 Neuroanesthesia and Cerebrospinal Protection. Springer Japan, p. 39-51 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

  12. Cyclosporine before PCI in Patients with Acute Myocardial Infarction

    Elmer, E. , Hansson, M. & 51 others Cung, T. -T., Morel, O., Cayla, G., Rioufol, G., Garcia-Dorado, D., Angoulvant, D., Bonnefoy-Cudraz, E., Guerin, P., Elbaz, M., Delarche, N., Coste, P., Vanzetto, G., Metge, M., Aupetit, J. -F., Jouve, B., Motreff, P., Tron, C., Labeque, J. -N., Steg, P. G., Cottin, Y., Range, G., Clerc, J., Claeys, M. J., Coussement, P., Prunier, F., Moulin, F., Roth, O., Belle, L., Dubois, P., Barragan, P., Gilard, M., Piot, C., Colin, P., De Poli, F., Morice, M. -C., Ider, O., Dubois-Rande, J. -L., Unterseeh, T., Le Breton, H., Beard, T., Blanchard, D., Grollier, G., Malquarti, V., Staat, P., Sudre, A., Bergerot, C., Boussaha, I., Jossan, C., Derumeaux, G., Mewton, N. & Ovize, M. 2015 In : New England Journal of Medicine. 373, 11, p. 1021-1031

    Research output: Contribution to journalArticle

  13. Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain.

    Kilbaugh, T. J., Michael Karlsson, Byro, M., Bebee, A., Ralston, J., Sullivan, S., Duhaime, A-C., Magnus Hansson, Eskil Elmer & Margulies, S. S. 2015 In : Experimental Neurology. 271, p. 136-144

    Research output: Contribution to journalArticle

  14. Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury.

    Kilbaugh, T. J., Michael Karlsson, Duhaime, A-C., Magnus Hansson, Eskil Elmer & Margulies, S. S. 2015 In : Mitochondrion.

    Research output: Contribution to journalArticle

  15. Persistently Altered Brain Mitochondrial Bioenergetics After Apparently Successful Resuscitation From Cardiac Arrest.

    Kilbaugh, T. J., Sutton, R. M., Michael Karlsson, Magnus Hansson, Naim, M. Y., Morgan, R. W., Bratinov, G., Lampe, J. W., Nadkarni, V. M., Becker, L. B., Margulies, S. S. & Berg, R. A. 2015 In : Journal of the American Heart Association. 4, p. 1-11 e002232

    Research output: Contribution to journalArticle

  16. The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1 beta

    Hansson, M. , Elmer, E. & 25 others Fujita, H., Yagishita, N., Aratani, S., Saito-Fujita, T., Morota, S., Yamano, Y., Inazu, M., Kokuba, H., Sudo, K., Sato, E., Kawahara, K., Nakajima, F., Hasegawa, D., Higuchi, I., Sato, T., Araya, N., Usui, C., Nishioka, K., Nakatani, Y., Maruyama, I., Usui, M., Hara, N., Uchino, H., Nishioka, K. & Nakajima, T. 2015 In : EMBO Journal. 34, 8, p. 1042-1055

    Research output: Contribution to journalArticle

  17. 2014
  18. 2013
  19. Cyclophilin-D inhibition in neuroprotection: dawn of a new era of mitochondrial medicine

    Uchino, H., Hatakeyama, K., Morota, S., Tanoue, T., Nishiyama, T., Usui, D., Taguchi, C., Suzuki, M., Magnus J Hansson & Eskil Elmér 2013 In : Acta Neurochirurgica. Supplementum. 118, p. 311-5 5 p.

    Research output: Contribution to journalArticle

  20. 2012
  21. Platelet mitochondrial function in sepsis.

    Fredrik Sjövall, Magnus Hansson & Eskil Elmer 2012 In : Critical Care Medicine. 40, 1, p. 357-357

    Research output: Contribution to journalArticle

  22. 2011
  23. Cyclophilin D-sensitive mitochondrial permeability transition in adult human brain and liver mitochondria.

    Magnus Hansson, Morota, S., Chen, L., Matsuyama, N., Suzuki, Y., Nakajima, S., Tanoue, T., Omi, A., Shibasaki, F., Shimazu, M., Ikeda, Y., Uchino, H. & Eskil Elmer 2011 In : Journal of Neurotrauma. 28, p. 143-153

    Research output: Contribution to journalArticle

  24. The GRACILE mutation introduced into Bcs1l causes postnatal complex III deficiency: A viable mouse model for mitochondrial hepatopathy.

    Levéen, P., Kotarsky, H., Mörgelin, M., Karikoski, R., Eskil Elmer & Vineta Fellman 2011 In : Hepatology. 53, 2, p. 437-447

    Research output: Contribution to journalArticle

  25. 2010
  26. Minocycline Sensitizes Rodent and Human Liver Mitochondria to the Permeability Transition: Implications for Toxicity in Liver Transplantation

    Månsson, R., Morota, S., Magnus Hansson, Sonoda, I., Yasuda, Y., Shimazu, M., Sugiura, A., Yanagi, S., Miura, H., Uchino, H. & Eskil Elmer 2010 In : Hepatology. 51, 1, p. 347-348

    Research output: Contribution to journalLetter

  27. 2009
  28. Evaluation of putative inhibitors of mitochondrial permeability transition for brain disorders - Specificity vs. toxicity.

    Morota, S., Månsson, R., Magnus Hansson, Kasuya, K., Shimazu, M., Hasegawa, E., Yanagi, S., Omi, A., Uchino, H. & Eskil Elmer 2009 In : Experimental Neurology. 218, p. 353-362

    Research output: Contribution to journalArticle

  29. 2008
  30. Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition.

    Magnus Hansson, Månsson, R., Morota, S., Uchino, H., Kallur, T., Sumi, T., Ishii, N., Shimazu, M., Keep, M. F., Jegorov, A. & Eskil Elmer 2008 In : Free Radical Biology & Medicine. 45, p. 284-294

    Research output: Contribution to journalArticle

  31. Probing the molecular mechanisms of neuronal degeneration: importance of mitochondrial dysfunction and calcineurin activation

    Uchino, H., Kuroda, Y., Morota, S., Hirabayashi, G., Ishii, N., Shibasaki, F., Ikeda, Y., Hansson, M. J. & Eskil Elmer 2008 In : Journal of Anesthesia. 22, 3, p. 253-262

    Research output: Contribution to journalReview article

  32. 2007