Paediatric Endocrinology

Organisational unit: Research group


The aim of our research is to identify genetic and immunological risk factors and predictive factors for type 1 diabetes, and ultimately to prevent the disease through primary or secondary prevention. The research is based upon our large prospective population-based studies. Diabetes Prediction in Skåne (DiPiS) and The Environmental Determinants of Diabetes in the young (TEDDY), screening for autoantibodies in relatives within TrialNet and a number of clinical trials aiming to prevent or delay the disease (Figure 1). In our prospective cohorts of children with risk for type 1 diabetes, we have shown that the children followed are diagnosed early with less symptom and serious disease. To prevent or delay type 1 diabetes in children with autoimmunity would be of uttermost importance.

Recent research outputs

Leal, G. F., Nishimura, G., Voss, U., Bertola, D. R., Åström, E., Johan Svensson, Yamamoto, G. L., Hammarsjö, A., Horemuzova, E., Papadiogannakis, N., Iwarsson, E., Grigelioniene, G. & Tham, E. 2018 Jan 4 In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Lynch, K. F., Lee, H-S., Törn, C., Vehik, K., Krischer, J. P., Helena Elding Larsson, Haller, M. J., Hagopian, W. A., Rewers, M. J., She, J-X., Simell, O. G., Toppari, J., Ziegler, A. G., Akolkar, B., Hyöty, H., Bonifacio, E., Åke Lernmark & TEDDY Study Group 2018 In : Journal of Autoimmunity. 86, p. 93-103

Research output: Contribution to journalArticle

Kemppainen, K. M. , Vehik, K. , Lynch, K. F. , Larsson, H. E. , Canepa, R. J. , Simell, V. , Koletzko, S. , Liu, E. , Simell, O. G. , Toppari, J. , Ziegler, A. G. , Rewers, M. J. , Lernmark, Å. , Hagopian, W. A. , She, J-X. , Akolkar, B. , Schatz, D. A. , Atkinson, M. A. , Blaser, M. J. , Krischer, J. P. & 4 others Hyöty, H., Daniel Agardh, Triplett, E. W. & Environmental Determinants of Diabetes in the Young (TEDDY) Study Group 2017 Dec 1 In : JAMA Pediatrics. 171, 12, p. 1217-1225 9 p.

Research output: Contribution to journalArticle

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