Personalized Breast Cancer Treatment

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology

Keywords

  • Breast cancer, prognosis, prediction, biomarkers, treatment

Research

Breast cancer is a heterogeneous disease with differences in clinical outcome and sensitivity to treatment. The choice of treatment after surgery (radiotherapy, antibodies, endocrine or chemo) is based on prognostic (risk of recurrence) and treatment predictive (choice of treatment) factors. About two thirds are cured after surgery, and still about 90% receive additional treatment. This means that some patients are over treated, but at the same time the treatment is lifesaving for others. It is extremely important to identify patients in need of additional treatment and, when needed, to choose the correct treatment. We are working towards new ways of looking at the information already collected and evaluated in the clinical routine but we’re also trying to identify new factors with both conventional techniques (e.g. immunohistochemistry) and new techniques (e.g. sequencing) that will help clinicians deciding what treatment or treatment combination will be best for the individual patient.

Recent research outputs

Anna Ehinger, Iiristo, M., Löfgren, L., Petersson, L-M. & Sandelin, K. 2017 Oct 6 Regionalt Cancercentrum Stockholm Gotland. 19 p.

Research output: Book/ReportReport

Martin Sjöström, Lundstedt, D., Linda Hartman, Holmberg, E., Killander, F., Kovács, A., Per Malmström, Emma Niméus, Rönnerman, E. W., Mårten Fernö & Karlsson, P. 2017 Oct 1 In : Journal of Clinical Oncology. 35, 28, p. 3222-3229 8 p.

Research output: Contribution to journalArticle

Anna Ehinger, Remse, I., Lövgren, K., Cecilia Hegardt, Jari Häkkinen, Lao Saal, Johan Vallon-Christersson & Åke Borg 2017 Sep 2 In : Virchows Archiv. 471, Supplement 1, p. 299 1 p., E-PS-02-027

Research output: Contribution to journalPublished meeting abstract

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