Stem Cells, Aging and Neurodegeneration

Organisational unit: Research group

Research areas and keywords

UKÄ subject classification

  • Neurology

Research

In our group we are interested in how aging and neurodegenerative diseases affect the brain, neural cells and neural stem cells. Using novel stem cell, reprogramming and genome editing technologies we are studying how genetic pathways involved in aging and neurodegenerative disease affect formation and function of neural cells. We also have a strong interest in basic stem cell biology with a clear focus on neural stem cells and neurogenesis in the adult and aging brain. Therefore, our aims are to develop cellular models of human neural aging and degeneration, to investigate underlying mechanisms responsible for dysfunction in neural and neural stem cells in the aging and diseased brain and to dissect the regulation of normal neurogenesis.

Recent research outputs

Isaac Canals, Ginisty, A., Ella Quist, Timmerman, R., Jonas Fritze, Giedre Miskinyte, Emanuela Monni, Hansen, M. G., Isabel Hidalgo, David Bryder, Johan Bengzon & Henrik Ahlenius, 2018 Aug 20, In : Nature Methods. 15, 9, p. 693-696 4 p.

Research output: Contribution to journalArticle

Chanoumidou, K., Hadjimichael, C., Athanasouli, P., Henrik Ahlenius, Klonizakis, A., Nikolaou, C., Drakos, E., Kostouros, A., Stratidaki, I., Grigoriou, M. & Kretsovali, A., 2018, In : Scientific Reports. 8, 1, 13790

Research output: Contribution to journalArticle

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