Division of Molecular Medicine and Gene Therapy

Organisational unit: Division

Description

Dysfunctional blood cell development can have fatal consequences on human health, with implications for several key areas of modern medicine, including amongst others the broad research areas of oncology and immunology. The Division of Molecular Hematology (DMH) aims to generate new knowledge about the regulation of blood cell development by applying recent advances in stem cell technology, in order to dissect the molecular regulation of hematopoiesis. Our mission is to translate this information into clinical contexts to advance the full potential of regenerative medicine.

Research

The department focuses on research that aims to develop gene therapy for hematopoietic cells using viral vectors. Hematopoiesis, in particular the genetic control of hematopoietic cell proliferation and differentiation is also studied in human cell cultures and transgenic mouse model systems.

Recent research outputs

Hammarström, H., Stjärne Aspelund, A., Bertil Christensson, Heußel, C. P., Isaksson, J., Kondori, N., Lennart Larsson, Markowicz, P., Johan Richter, Wennerås, C. & Friman, V., 2018 Sep 1, In : Mycoses. 61, 9, p. 623-632 10 p.

Research output: Contribution to journalArticle

Stefan Karlsson, 2018 Jul 19, In : New England Journal of Medicine. 379, 3, p. 295-296 2 p.

Research output: Contribution to journalDebate/Note/Editorial

Massaro, G. , Mattar, C. N. Z. , Wong, A. M. S. , Sirka, E. , Buckley, S. M. K. , Herbert, B. R. , Karlsson, S. , Perocheau, D. P. , Burke, D. , Heales, S. , Richard-Londt, A. , Brandner, S. , Huebecker, M. , Priestman, D. A. , Platt, F. M. , Mills, K. , Biswas, A. , Cooper, J. D. , Chan, J. K. Y. , Cheng, S. H. & 2 others Waddington, S. N. & Rahim, A. A., 2018 Jul 16, In : Nature Medicine. 7 p.

Research output: Contribution to journalLetter

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