Bo Åkerström

Professor
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  1. 2017
  2. Recombinant alpha-1-microglobulin: A potential treatment for preeclampsia

    Gunnarsson, R., Bo Åkerström, Stefan R. Hansson & Magnus Gram 2017 In : Drug Discovery Today. 22, 4, p. 736-743

    Research output: Contribution to journalReview article

  3. The Role of Mitochondria, Oxidative Stress, and the Radical-binding Protein A1M in Cultured Porcine Retina.

    Bo Åkerström, CEDERLUND, M. A. R. T. I. N., Jesper Bergwik, Oscar Manouchehrian, Arnér, K., Holmgren Taylor, I., Fredrik Ghosh & Linnéa Taylor 2017 In : Current Eye Research. 42, 6, p. 948-961

    Research output: Contribution to journalArticle

  4. 2016
  5. Fetal hemoglobin, α1-microglobulin and hemopexin are potential predictive first trimester biomarkers for preeclampsia

    DOLBERG ANDERSON, U. L. R. I. K., Magnus Gram, Jonas Ranstam, Thilaganathan, B., Bo Åkerström & Hansson, S. R. 2016 Apr 1 In : Pregnancy Hypertension. 6, 2, p. 103-109 7 p.

    Research output: Contribution to journalArticle

  6. Influence of nanomechanical stress induced by ZnO nanoparticles of different shapes on the viability of cells

    Matuła, K., Richter, Ł., Adamkiewicz, W., Bo Åkerström, Paczesny, J. & Hołyst, R. 2016 In : Soft Matter. 12, 18, p. 4162-4169 8 p.

    Research output: Contribution to journalArticle

  7. Structural and biochemical characterization of two heme binding sites on α1-microglobulin using site directed mutagenesis and molecular simulation.

    Rutardottir, S., Karnaukhova, E., Nantasenamat, C., Songtawee, N., Prachayasittikul, V., Rajabi, M., Wester Rosenlöf, L., Alayash, A. I. & Bo Åkerström 2016 In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1864, 1, p. 29-41

    Research output: Contribution to journalArticle

  8. 2015
  9. A1M Ameliorates Preeclampsia-Like Symptoms in Placenta and Kidney Induced by Cell-Free Fetal Hemoglobin in Rabbit.

    Åsa Nääv, Lena Erlandsson, Axelsson, J., Larsson, I., Martin Johansson, Wester Rosenlöf, L., Mörgelin, M., Vera Casslén, Magnus Gram, Bo Åkerström & Stefan Hansson 2015 In : PLoS ONE. 10, 5, e0125499

    Research output: Contribution to journalArticle

  10. First Trimester Prediction of Preeclampsia.

    Dolberg Anderson, U., Magnus Gram, Bo Åkerström & Hansson, S. R. 2015 In : Current Hypertension Reports. 17, 9, p. 74

    Research output: Contribution to journalReview article

  11. Heme-induced contractile dysfunction in Human cardiomyocytes caused by oxidant damage to thick filament proteins.

    Alvarado, G., Jeney, V., Tóth, A., Csősz, É., Kalló, G., An Huynh, T., Hajnal, C., Kalász, J., Pásztor, E. T., Édes, I., Magnus Gram, Bo Åkerström, Smith, A., Eaton, J. W., Balla, G., Papp, Z. & Balla, J. 2015 In : Free Radical Biology & Medicine. 89, sep 23, p. 248-262

    Research output: Contribution to journalArticle

  12. The Human Endogenous Protection System against Cell-Free Hemoglobin and Heme Is Overwhelmed in Preeclampsia and Provides Potential Biomarkers and Clinical Indicators.

    Magnus Gram, Dolberg Anderson, U., Johansson, M. E., Edström, A., Larsson, I., Maya Jälmby, Hansson, S. R. & Bo Åkerström 2015 In : PLoS ONE. 10, 9, e0138111

    Research output: Contribution to journalArticle

  13. 2014
  14. A1M, an extravascular tissue cleaning and housekeeping protein.

    Bo Åkerström & Magnus Gram 2014 In : Free Radical Biology & Medicine. 74, p. 274-282

    Research output: Contribution to journalReview article

  15. A1M, an extravascular tissue cleaning and housekeeping protein: a possible drug candidate

    Magnus Gram & Bo Åkerström 2014 In : Free Radical Biology and Medicine. 75 Suppl 1, p. S31

    Research output: Contribution to journalPublished meeting abstract

  16. A1M/α1-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia.

    Wester Rosenlöf, L., Vera Casslén, Axelsson, J., Edström, A., Magnus Gram, Holmqvist, M., Martin Johansson, Larsson, I., David Ley, Karel Marsal, Mörgelin, M., Rippe, B., Rutardottir, S., Shohani, B., Bo Åkerström & Stefan Hansson 2014 In : PLoS ONE. 9, 1, e86353

    Research output: Contribution to journalArticle

  17. Characterization of heme binding to recombinant α1-microglobulin.

    Karnaukhova, E., Rutardottir, S., Rajabi, M., Wester Rosenlöf, L., Alayash, A. I. & Bo Åkerström 2014 In : Frontiers in Physiology. 5, 465

    Research output: Contribution to journalArticle

  18. Extracellular fetal hemoglobin induces increases in glomerular permeability: inhibition with alfa-1-microglobulin and tempol

    Sverrisson, K., Axelsson, J., Rippe, A., Magnus Gram, Bo Åkerström, Stefan Hansson & Rippe, B. 2014 In : American Journal of Physiology-Renal Physiology. 306, 4, p. F442-F448

    Research output: Contribution to journalArticle

  19. Syncytiotrophoblast Vesicles Show Altered micro-RNA and Haemoglobin Content after Ex-vivo Perfusion of Placentas with Haemoglobin to Mimic Preeclampsia.

    Tina Cronqvist, Saljé, K., Familari, M., Guller, S., Schneider, H., Gardiner, C., Sargent, I. L., Redman, C. W., Mörgelin, M., Bo Åkerström, Magnus Gram & Stefan Hansson 2014 In : PLoS ONE. 9, 2, e90020

    Research output: Contribution to journalArticle

  20. 2013
  21. Homozygosity for a null allele of SMIM1 defines the Vel-negative blood group phenotype.

    Jill Storry, Magnus Jöud, Christophersen, M. K., Thuresson, B., Bo Åkerström, Sojka, B. N., Björn Nilsson & Martin L Olsson 2013 In : Nature Genetics. 45, 5, p. 537-U109

    Research output: Contribution to journalArticle

  22. The radical-binding lipocalin A1M binds to a Complex I subunit and protects mitochondrial structure and function.

    Magnus Gram, Wester Rosenlöf, L., Kotarsky, H., Olofsson, T., Tomas Leanderson, Mörgelin, M., Vineta Fellman & Bo Åkerström 2013 In : Antioxidants & Redox Signaling. 18, 16, p. 2017-2028

    Research output: Contribution to journalArticle

  23. 2012
  24. Increased levels of hemoglobin and alpha1-microglobulin in Huntington's disease.

    Magnus Gram, Davidsson, S., Muhammad, Z. D., Lahiri, N., Tabrizi, S. J., Bo Åkerström & Maria Björkqvist 2012 In : Frontiers in Bioscience (Elite Edition). 4, p. 950-957

    Research output: Contribution to journalArticle

  25. Insertion of Heme b into the Structure of the Cys34-Carbamidomethylated Human Lipocalin a1-Microglobulin: Formation of a [(Heme)2(a1-Microglobulin)]3 Complex

    Siebel, J. F., Kosinsky, R. L., Bo Åkerström & Knipp, M. 2012 In : ChemBioChem. 13, 6, p. 879-887

    Research output: Contribution to journalArticle

  26. Review: Biochemical markers to predict preeclampsia.

    Dolberg Anderson, U., Olsson, M. G., Kristensen, K., Bo Åkerström & Stefan Hansson 2012 In : Placenta. 33, p. S42-S47

    Research output: Contribution to journalArticle

  27. 2011
  28. Fetal hemoglobin and alpha(1)-microglobulin as first- and early second-trimester predictive biomarkers for preeclampsia

    Dolberg Anderson, U., Magnus Gram, Rutardottir, S., Centlow, M., Kristensen, K., Per-Erik Isberg, Thilaganathan, B., Bo Åkerström & Stefan Hansson 2011 In : American Journal of Obstetrics and Gynecology. 204, 6

    Research output: Contribution to journalArticle

  29. Orsaken till preeklampsi på väg att klarläggas. Fetalt hemoglobin kan vara nyckeln till prediktion, diagnostik och behandling.

    Stefan Hansson, Dolberg Anderson, U., Centlow, M., Magnus Gram & Bo Åkerström 2011 In : Läkartidningen. 108, 43, p. 2151-2156

    Research output: Contribution to journalArticle

  30. Perfusion of human placenta with hemoglobin introduces preeclampsia-like injuries that are prevented by α(1)-microglobulin.

    May, K., Wester Rosenlöf, L., Magnus Gram, Centlow, M., Mörgelin, M., Larsson, I., Cederlund, M., Rutardottir, S., Siegmund, W., Schneider, H., Bo Åkerström & Stefan Hansson 2011 In : Placenta. 32, 4, p. 323-332

    Research output: Contribution to journalArticle

  31. Up-Regulation of A1M/α(1)-Microglobulin in Skin by Heme and Reactive Oxygen Species Gives Protection from Oxidative Damage.

    Magnus Gram, Maria Allhorn, Larsson, J. G., Cederlund, M., Lundqvist, K., Artur Schmidtchen, Ole E Sørensen, Mörgelin, M. & Bo Åkerström 2011 In : PLoS ONE. 6, 11, e27505

    Research output: Contribution to journalArticle

  32. 2010
  33. Increased levels of cell-free hemoglobin, oxidation markers, and the antioxidative heme scavenger alpha(1)-microglobulin in preeclampsia.

    Magnus Gram, Centlow, M., Rutardottir, S., Stenfors, I., Larsson, J. G., Hosseini Maaf, B., Martin L Olsson, Stefan Hansson & Bo Åkerström 2010 In : Free Radical Biology & Medicine. 48, p. 284-291

    Research output: Contribution to journalArticle

  34. Investigation into the Carrier Molecule of the Vel Blood Group Antigen

    Jill Storry, Bo Åkerström & Martin L Olsson 2010 In : Transfusion. 50, p. 28A-28A

    Research output: Contribution to journalPublished meeting abstract

  35. Perfusion Of Human Placenta With Hemoglobin, Introduces Preeclampsia-Like Injuries That Are Prevented By Alpha 1-Microglobulin

    May, K., Rosenlöf, L., Magnus Gram, Centlow, M., Mörgelin, M., Larsson, I., Cederlund, M., Rutardottir, S., Schneider, H., Siegmund, W., Bo Åkerström & Stefan Hansson 2010 In : Placenta. 31, 9, p. A125-A125

    Research output: Contribution to journalPublished meeting abstract

  36. 2009
  37. At the Tip of an MeV Beam: Provoking Cells and Performing Tomographic Imaging

    Jan Pallon, Arteaga, N., Charlotta Nilsson, Mikael Elfman, Per Kristiansson, Nilsson, C., Wegdén, M., Magnus Gram & Bo Åkerström 2009 Acta Physica Polonica A. Jagellonian University, Cracow, Poland, Vol. 115, p. 501-506

    Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

  38. Die in-vitro Perfusion der menschlichen Plazenta mit Eryhtrozyten und Xanthine Oxidase als in vitro Simulation von Praeeklampsie.

    Centlow, M., Junus, K., Nyström, H., May, K., Larsson, I., Olsson, M. G., Bo Åkerström, Sager, R., Schneider, H. & Hansson, S. R. 2009 In : Zeitschrift für Geburtshilfe und Neonatologie. 213, 3, p. 89-95

    Research output: Contribution to journalArticle

  39. 2008
  40. Effects of free hemoglobin on the human placenta; An in-vitro study using the placenta dual-perfusion system

    Centlow, M., May, K., Olsson, M. G., Schneider, H., Bo Åkerström & Stefan Hansson 2008 In : Placenta. 29, 8, p. A79-A79

    Research output: Contribution to journalPublished meeting abstract

  41. Molecular interactions of the neuronal GPI-anchored lipocalin Lazarillo

    Sanchez, D., Ortega-Cubero, S., Bo Åkerström, Herrera, M., Bastiani, M. J. & Ganfornina, M. D. 2008 In : Journal of Molecular Recognition. 21, 5, p. 312-322

    Research output: Contribution to journalArticle

  42. 2007
  43. Production of recombinant human alpha(1)-microglobulin and mutant forms involved in chromophore formation

    Kwasek, A., Osmark, P., Maria Allhorn, Lindqvist, A., Bo Åkerström & Wasylewski, Z. 2007 In : Protein Expression and Purification. 53, 1, p. 145-152

    Research output: Contribution to journalArticle

  44. The lipocalin alpha 1-microglobulin has radical scavenger activity.

    Bo Åkerström, Maghzal, G., Winterbourn, C. C. & Kettle, A. J. 2007 In : Journal of Biological Chemistry. 282, 43, p. 31493-31503

    Research output: Contribution to journalArticle

  45. 2006
  46. Alpha(1)-microglobulin.

    Bo Åkerström & Lögdberg, L. 2006 Lipocalins. B., A., N., B., D., F. & J.-P., S. (eds.). Landes Bioscience, p. 110

    Research output: Chapter in Book/Report/Conference proceedingBook chapter

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