Carola Tilgmann

Research Communication Officer, PhD, Adjunct Prof, Library Information Science Competence , Adjunct Professor , PhD, Master in Biochemistry and Food Chemistry
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  1. 2016
  2. En omvärldsanalys kring datahanteringsplaner

    Johnsson, M., Carola Tilgmann, Matthias Bank, Yvonne Hultman Özek, Monica Lassi, Jörgen Eriksson & Smith, C. 2016 Nov 10 Lunds universitet

    Research output: Other contributionMiscellaneous

  3. 2015
  4. 2014
  5. Supporting Researchers - Back to the Future!

    Yvonne Hultman Özek, Carola Tilgmann & Matthias Bank 2014

    Research output: Contribution to conferencePoster

  6. The State of The Research

    Carola Tilgmann, Graffner, M., Bristulf, J. & Yvonne Hultman Özek 2014

    Research output: Contribution to conferencePoster

  7. 2013
  8. Discovery and Structural Characterization of a Phospholamban-Binding Cyclic Peptide and Design of Novel Inhibitors of Phospholamban

    Carola Tilgmann, Pollesello, P., Ovaska, M., Kaivola, J., Pystynen, J., Tiainen, E., Yliperttula, M., Annila, A. & Levijoki, J. 2013 Apr In : Chemical Biology and Drug Design. 81, 4, p. 463-473 11 p.

    Research output: Contribution to journalArticle

  9. 2012
  10. Method for the prevention of thromboembolic disorders

    Haikala, H., Levijoki, J., Pollesello, P. & Carola Tilgmann 2012 Dec 11 US 08329693

    Research output: Patent

  11. 2011
  12. Phenotype mining in CNV carriers from a population cohort

    Pietiläinen, O. P. H., Rehnström, K., Jakkula, E., Service, S. K., Congdon, E., Carola Tilgmann, Hartikainen, A. L., Taanila, A., Heikura, U., Paunio, T., Ripatti, S., Jarvelin, M. R., Isohanni, M., Sabatti, C., Palotie, A., Freimer, N. B. & Peltonen, L. 2011 Jul In : Human Molecular Genetics. 20, 13, p. 2686-2695 10 p., ddr162

    Research output: Contribution to journalArticle

  13. 2007
  14. Increased catechol-O-methyltransferase activity and protein expression in OX-42-positive cells in the substantia nigra after lipopolysaccharide microinfusion

    Helkamaa, T., Reenilä, I., Tuominen, R. K., Soinila, S., Väänänen, A., Carola Tilgmann & Rauhala, P. 2007 Nov In : Neurochemistry International. 51, 6-7, p. 412-423 12 p.

    Research output: Contribution to journalArticle

  15. 2006
  16. Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas

    Salama, S. A., Ho, S. L., Wang, H. Q., Tenhunen, J., Carola Tilgmann & Al-Hendy, A. 2006 Jul In : Fertility and Sterility. 86, 1, p. 259-262 4 p.

    Research output: Contribution to journalArticle

  17. 2004
  18. Compounds for deactivating phospholamban function on Ca-ATPase (phospholamban inhibitors)

    Pollesello, P., Ovaska, M., Tenhunen, J., Vidgren, J., Yliperttula, M., Carola Tilgmann, Lotta, T. & Kaivola, J. 2004 Aug 10 US 6774103 B1

    Research output: Patent

  19. 2003
  20. Reduced membrane-bound catechol-O-methyltransferase in the liver of spontaneously hypertensive rats

    Tsunoda, M., Tenhunen, J., Carola Tilgmann, Arai, H. & Imai, K. 2003 Nov In : Hypertension Research. 26, 11, p. 923-927 5 p.

    Research output: Contribution to journalArticle

  21. 2001
  22. Phospholamban inhibitors and a method for increasing coronary flow

    Pystynen, J., Haikala, H., P, K., Kaivola, J., Pollesello, P., Ulmanen, I., Tenhunen, J., Carola Tilgmann, Tiainen, E., K, L., P, N., S, P., A, K. & Levijoki, J. 2001 Jul 24 US 6265421

    Research output: Patent

  23. Binding of Levosimendan, a Calcium Sensitizer, to Cardiac Troponin C

    Sorsa, T., Heikkinen, S., Abbott, M. B., Abusamhadneh, E., Laakso, T., Carola Tilgmann, Serimaa, R., Annila, A., Rosevear, P. R., Torbjörn Drakenberg, Pollesello, P. & Kilpeläinen, I. 2001 Mar 23 In : Journal of Biological Chemistry. 276, 12, p. 9337-9343 7 p.

    Research output: Contribution to journalArticle

  24. The enhanced contractility of the phospholamban-deficient mouse heart persists with aging

    Slack, J. P., Grupp, I. L., Dash, R., Holder, D., Schmidt, A., Gerst, M. J., Tamura, T., C. Tilgmann, P. F. James, Johnson, R., Gerdes, A. M. & Kranias, E. G. 2001 In : Journal of Molecular and Cellular Cardiology. 33, 5, p. 1031-1040 10 p.

    Research output: Contribution to journalArticle

  25. 2000
  26. Regulatory role of phospholamban in the efficiency of cardiac sarcoplasmic reticulum Ca2+ transport

    Frank, K., C. Tilgmann, Shannon, T. R., Bers, D. M. & Kranias, E. G. 2000 Nov 21 In : Biochemistry. 39, 46, p. 14176-14182 7 p.

    Research output: Contribution to journalArticle

  27. Conformations of the regulatory domain of cardiac troponin C examined by residual dipolar couplings

    Pääkkönen, K., Sorsa, T., Torbjörn Drakenberg, Pollesello, P., Carola Tilgmann, Permi, P., Heikkinen, S., Kilpeläinen, I. & Annila, A. 2000 In : European Journal of Biochemistry. 267, 22, p. 6665-6672 8 p.

    Research output: Contribution to journalArticle

  28. Further evidence for the cardiac troponin C mediated calcium sensitization by levosimendan: Structure-response and binding analysis with analogs of levosimendan

    Levijoki, J., Pollesello, P., Kaivola, J., Carola Tilgmann, Sorsa, T., Annila, A., Kilpeläinen, I. & Haikala, H. 2000 In : Journal of Molecular and Cellular Cardiology. 32, 3, p. 479-491 13 p.

    Research output: Contribution to journalArticle

  29. 1998
  30. Solution structure and main chain dynamics of the regulatory domain (Residues 1-91) of human cardiac troponin C

    Pääkkönen, K., Annila, A., Sorsa, T., Pollesello, P., Carola Tilgmann, Kilpeläinen, I., Karisola, P., Ulmanen, I. & Torbjörn Drakenberg 1998 Jun 19 In : Journal of Biological Chemistry. 273, 25, p. 15633-15638 6 p.

    Research output: Contribution to journalArticle

  31. 1997
  32. Effects of age on the hyperdynamic cardiac function of phospholamban knockout mice

    Slack, J. P., Grupp, I., Carola Tilgmann, LUO, W., Tamura, T., Gerdes, M. & Kranias, E. 1997 In : Circulation. 96, 8 Suppl, p. I179

    Research output: Contribution to journalPublished meeting abstract

  33. Expression and intracellular localization of catechol O-methyltransferase in transfected mammalian cells

    Ulmanen, I., Peränen, J., Tenhunen, J., Carola Tilgmann, Karhunen, T., Panula, P., Bernasconi, L., Aubry, J. P. & Lundström, K. 1997 In : European Journal of Biochemistry. 243, 1-2, p. 452-459 8 p.

    Research output: Contribution to journalArticle

  34. Molecular biology of COMT

    Ulmanen, I., Savolainen, R., Tenhunen, J., Carola Tilgmann & Syvänen, A-C. 1997 In : Pharmacology and Toxicology. 81, Suppl 1, p. 11 1 p.

    Research output: Contribution to journalPublished meeting abstract

  35. 1996
  36. Purification methods of mammalian catechol-O-methyltransferase

    Carola Tilgmann & Ulmanen, I. 1996 Jul 20 In : Journal of chromatography. B, Biomedical applications. 684, 1-2, p. 147-161 15 p.

    Research output: Contribution to journalArticle

  37. Compensatory mechanisms associated with the hyperdynamic function of phospholamban-deficient mouse hearts

    Chu, G., Luo, W., Slack, J. P., Carola Tilgmann, Sweet, W. E., Spindler, M., Saupe, K. W., Boivin, G. P., Moravec, C. S., Matlib, M. A., Grupp, I. L., Ingwall, J. S. & Kranias, E. G. 1996 In : Circulation Research. 79, 6, p. 1064-1076 13 p.

    Research output: Contribution to journalArticle

  38. 1995
  39. Cloning, expression and structure of catechol-O-methyltransferase

    Lundström, K., Tenhunen, J., Carola Tilgmann, Karhunen, T., Panula, P. & Ulmanen, I. 1995 Aug 16 In : BBA - Protein Structure and Molecular Enzymology. 1251, 1, p. 1-10 10 p.

    Research output: Contribution to journalArticle

  40. Catechol-O-methyltransferase (COMT) in rat brain: immunoelectron microscopic study with an antiserum against rat recombinant COMT protein

    Karhunen, T., Carola Tilgmann, Ulmanen, I. & Panul, P. 1995 Feb 24 In : Neuroscience Letters. 187, 1, p. 57-60 4 p.

    Research output: Contribution to journalArticle

  41. Effects of signal peptide mutations on processing of Bacillus stearothermophilus α-amylase in Escherichia coli

    Suominen, I., Meyer, P., C. Tilgmann, Glumoff, T., Glumoff, V., Kapyla, J. & Mantsala, P. 1995 In : Microbiology. 141, 3, p. 649-654 6 p.

    Research output: Contribution to journalArticle

  42. Kinetics of human soluble and membrane-bound catechol O- methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme

    Lotta, T., Vidgren, J., C. Tilgmann, Ulmanen, I., Melen, K., Julkunen, I. & Taskinen, J. 1995 In : Biochemistry. 34, 13, p. 4202-4210 9 p.

    Research output: Contribution to journalArticle

  43. Neuronal and non-neuronal catechol-O-methyltransferase in primary cultures of rat brain cells

    Karhunen, T., C. Tilgmann, Ulmanen, I. & Panula, P. 1995 In : International Journal of Developmental Neuroscience. 13, 8, p. 825-834 10 p.

    Research output: Contribution to journalArticle

  44. Opposite effect of ethanol on recombinant membrane-bound and soluble activities of catechol-O-methyltransferase

    Reenila, I., Tuomainen, P., C. Tilgmann & Mannisto, P. T. 1995 In : Pharmacology and Toxicology. 77, 6, p. 414-416 3 p.

    Research output: Contribution to journalArticle

  45. 1994
  46. O-methylation of L-dopa in melanin metabolism and the presence of catechol-O-methyltransferase in melanocytes.

    Smit, N., C. Tilgmann, Karhunen, T., Slingerland, R., Ulmanen, I., Westerhof, W. & Pavel, S. 1994 Dec In : Pigment Cell Research. 7, 6, p. 403-408 6 p.

    Research output: Contribution to journalArticle

  47. Binding of a new Ca2+ sensitizer, levosimendan, to recombinant human cardiac troponin C: A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study

    Pollesello, P., Ovaskai, M., Kaivola, J., Carola Tilgmann, Lundström, K., Kalkkinen, N., Ulmanen, I., Nissinen, E. & Taskinen, J. 1994 Nov 18 In : Journal of Biological Chemistry. 269, 46, p. 28584-28590 7 p.

    Research output: Contribution to journalArticle

  48. Catechol-O-methyltransferase in human brain

    Karhunen, T., Carola Tilgmann, Kalimo, H. & Ulmanen, I. 1994 In : Society for Neuroscience Abstracts. 20, 1-2, p. 916-916

    Research output: Contribution to journalPublished meeting abstract

  49. Distribution of catechol-O-methyltransferase enzyme in rat tissues

    Karhunen, T., C. Tilgmann, Ulmanen, I., Julkunen, I. & Panula, P. 1994 In : Journal of Histochemistry and Cytochemistry. 42, 8, p. 1079-1090 12 p.

    Research output: Contribution to journalArticle

  50. 1993
  51. Cellular and subcellular localization of COMT enzyme in rat brain and cell lines expressing recombinant rat enzyme

    Karhunen, T., Carola Tilgmann, Peranen, J., I, U. & P, P. 1993 Nov In : Society for Neuroscience Abstracts. 19, 1-3, p. 739 739 p.

    Research output: Contribution to journalPublished meeting abstract

  52. Purification, Molecular Cloning and Expression of rat and human Catechol-O-methyltransferases

    Carola Tilgmann 1993 Aug 27 Helsinki: Helsingin Yliopisto. 53 p.

    Research output: ThesisDoctoral Thesis (compilation)

  53. 1992
  54. Aspartic proteinase from barley grains is related to mammalian lysosomal cathepsin D

    Sarkkinen, P., Kalkkinen, N., Carola Tilgmann, Siuro, J., Kervinen, J. & Mikola, L. 1992 Feb In : Planta. 186, 3, p. 317-323 7 p.

    Research output: Contribution to journalArticle

  55. Characteristics of catechol O-methyltransferase (COMT) and properties of selective COMT inhibitors

    Mannisto, P. T., Ulmanen, I., Lundstrom, K., Taskinen, J., Tenhunen, J., C. Tilgmann & Kaakkola, S. 1992 In : Progress in Drug Research. 39, p. 291-350 60 p.

    Research output: Contribution to journalArticle

  56. Expression of catechol-O-methyltransferase (COMT) in rat brain and peripheral tissues

    Karhunen, T., Carola Tilgmann, Julkunen, I., Ulmanen, I. & Panula, P. 1992 In : Society for Neuroscience Abstracts. 18, 1-2, p. 1385-1385

    Research output: Contribution to journalPublished meeting abstract

  57. Expression of recombinant soluble and membrane-bound catechol O-methyltransferase in eukaryotic cells and identification of the respective enzymes in rat brain

    C. Tilgmann, Melen, K., Lundstrom, K., Jalanko, A., Julkunen, I., Kalkkinen, N. & Ulmanen, I. 1992 In : European Journal of Biochemistry. 207, 2, p. 813-821 9 p.

    Research output: Contribution to journalArticle

  58. 1991
  59. Catechol-o-methyltransferase, polypeptide sequences and dna molecule coding therefor

    Jalanko, A., Kalkkinen, N., Lundström, K., Salminen, M., H, S., Carola Tilgmann & Ulmanen, I. 1991 Oct 17 WO1991011513 A3

    Research output: Patent

  60. Aspartic proteinase from barley seeds is related to animal cathepsin D

    Tormakangas, K., Runeberg-Roos, P., Ostman, A., C. Tilgmann, Sarkkinen, P., Kervinen, J., Mikola, L. & Kalkkinen, N. 1991 In : Advances in Experimental Medicine and Biology. 306, p. 355-359 5 p.

    Research output: Contribution to journalArticle

  61. Crystallization and preliminary X-ray investigation of a recombinant form of rat catechol O-methyltransferase

    Vidgren, J., C. Tilgmann, Lundstrom, K. & A. Liljas 1991 In : Proteins. 11, 3, p. 233-236 4 p.

    Research output: Contribution to journalArticle

  62. 1990
  63. Purification and partial characterization of rat liver soluble catechol- O-methyltransferase

    Carola Tilgmann & Kalkkinen, N. 1990 May 7 In : FEBS Letters. 264, 1, p. 95-99 5 p.

    Research output: Contribution to journalArticle

  64. CLONING AND EXPRESSION OF RAT CATECHOL-O-METHYLTRANSFERASE COMT

    Lundström, K., Salminen, M., Jalanko, A., Panula, P., Castrén, E., Karhunen, T., Carola Tilgmann, Kalkkinen, N. & Ulmanen, I. 1990 In : Journal of Cellular Biochemistry. 14 part F, p. 61 1 p.

    Research output: Contribution to journalPublished meeting abstract

  65. Molecular cloning and characterization of rat liver catechol-O-methyltransferase

    Salminen, M., Lundström, K., Carola Tilgmann, Savolainen, R., Kalkkinen, N. & Ulmanen, I. 1990 In : Gene. 93, 2, p. 241-247 7 p.

    Research output: Contribution to journalArticle

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