Eva Degerman

Professor
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  1. 2018
  2. 2017
  3. Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes

    Johanna Säll, Pettersson, A. M. L., Björk, C., Henriksson, E., Sebastian Wasserstrom, Linder, W., Zhou, Y., Ola Hansson, Andersson, D. P., Mikael Ekelund, Eva Degerman, Karin G Stenkula, Laurencikiene, J. & Olga Göransson, 2017 Feb, In : Diabetologia. 60, 2, p. 314–323

    Research output: Contribution to journalArticle

  4. White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function

    Chung, Y. W., Ahmad, F., Tang, Y., Hockman, S. C., Kee, H. J., Karin Berger, Guirguis, E., Choi, Y. H., Schimel, D. M., Aponte, A. M., Park, S., Eva Degerman & Manganiello, V. C., 2017 Jan 13, In : Scientific Reports. 7, 40445

    Research output: Contribution to journalArticle

  5. 2016
  6. Parathyroid hormone induces adipocyte lipolysis via PKA-mediated phosphorylation of hormone-sensitive lipase.

    Larsson, S., Jones, H., Olga Göransson, Eva Degerman & Cecilia Holm, 2016, In : Cellular Signalling. 28, 3, p. 204-213

    Research output: Contribution to journalArticle

  7. 2015
  8. Cyclic Nucleotide Phosphodiesterases: important signaling modulators and therapeutic targets

    Ahmad, F., Murata, T., Shimizu, K., Eva Degerman, Maurice, D. & Manganiello, V., 2015, In : Oral Diseases. 21, 1, p. E25-E50

    Research output: Contribution to journalReview article

  9. Regulation of SERCA2 activity by PDE3A in human myocardium: Phosphorylation-dependent interaction of PDE3A1 with SERCA2.

    Ahmad, F., Shen, W., Vandeput, F., Szabo-Fresnais, N., Krall, J., Eva Degerman, Goetz, F., Klussmann, E., Movsesian, M. & Manganiello, V., 2015, In : Journal of Biological Chemistry. 290, 11, p. 6763-6776

    Research output: Contribution to journalArticle

  10. SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes

    Henriksson, E., Johanna Sernevi Säll, Gormand, A., Sebastian Wasserstrom, Morrice, N. A., Fritzen, A. M., Foretz, M., Campbell, D. G., Sakamoto, K., Mikael Ekelund, Eva Degerman, Karin Stenkula & Olga Göransson, 2015, In : Journal of Cell Science. 128, 3, p. 472-486

    Research output: Contribution to journalArticle

  11. 2014
  12. 2013
  13. A link between GIP and osteopontin in adipose tissue and insulin resistance.

    Ahlqvist, E. , Osmark, P. , Kuulasmaa, T. , Pilgaard, K. , Omar, B. , Brøns, C. , Kotova, O. , Zetterqvist, A. , Stancáková, A. , Jonsson, A. , Hansson, O. , Kuusisto, J. , Kieffer, T. J. , Tuomi, T. , Isomaa, B. , Madsbad, S. , Gomez, M. F. , Poulsen, P. , Laakso, M. , Degerman, E. & 5 others Pihlajamäki, J., Nils Wierup, Allan Vaag, Leif Groop & Valeriya Lyssenko, 2013, In : Diabetes. 62, 6, p. 2088-2094

    Research output: Contribution to journalArticle

  14. A Role for Phosphodiesterase 3B in Acquisition of Brown Fat Characteristics by White Adipose Tissue in Male Mice.

    Guirguis, E., Hockman, S., Chung, Y. W., Ahmad, F., Gavrilova, O., Raghavachari, N., Yang, Y., Niu, G., Chen, X., Yu, Z. X., Liu, S., Eva Degerman & Manganiello, V., 2013, In : Endocrinology. 154, 9, p. 3152-3167

    Research output: Contribution to journalArticle

  15. Expression of insulin signalling components in the sensory epithelium of the human saccule.

    Eva Degerman, Uwe Rauch, Lindberg, S., Caye-Thomasen, P., Anna Hultgårdh & Måns Magnusson, 2013, In : Cell and Tissue Research. 352, 3, p. 469-478

    Research output: Contribution to journalArticle

  16. 2012
  17. Cyclic Nucleotide Phosphodiesterase 3 Signaling Complexes

    Ahmad, F., Eva Degerman & Manganiello, V. C., 2012, In : Hormone and Metabolic Research. 44, 10, p. 776-785

    Research output: Contribution to journalReview article

  18. Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.

    Andersson, S. A., Olsson, A. H., Esguerra, J. L. S., Heimann, E., Ladenvall, C., Anna Edlund, S Albert Salehi, Taneera, J., Eva Degerman, Leif Groop, Charlotte Ling & Lena Eliasson, 2012, In : Molecular and Cellular Endocrinology. 364, 1-2, p. 36-45

    Research output: Contribution to journalArticle

  19. Role of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion

    Tian, G., Sagetorp, J., Xu, Y., Shuai, H., Eva Degerman & Tengholm, A., 2012, In : Journal of Cell Science. 125, 21, p. 5084-5095

    Research output: Contribution to journalArticle

  20. 2011
  21. From PDE3B to the regulation of energy homeostasis.

    Eva Degerman, Ahmad, F., Chung, Y. W., Guirguis, E., Omar, B., Stenson, L. & Manganiello, V., 2011, In : Current Opinion in Pharmacology. 11, p. 676-682

    Research output: Contribution to journalArticle

  22. Insulin Reduces Neuronal Excitability by Turning on GABA(A) Channels that Generate Tonic Current

    Jin, Z., Jin, Y., Kumar-Mendu, S., Eva Degerman, Leif Groop & Birnir, B., 2011, In : PLoS ONE. 6, 1

    Research output: Contribution to journalArticle

  23. Salicylamide and salicylglycine oxidovanadium complexes with insulin-mimetic properties.

    Nilsson, J., Shteinman, A. A., Eva Degerman, Enyedy, E. A., Kiss, T., Behrens, U., Rehder, D. & Nordlander, E., 2011, In : Journal of Inorganic Biochemistry. 105, p. 1795-1800

    Research output: Contribution to journalArticle

  24. 2010
  25. Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.

    Heimann, E., Jones, H., Resjö, S., Manganiello, V. C., Stenson, L. & Eva Degerman, 2010, In : PLoS ONE. 5, 12, e14191

    Research output: Contribution to journalArticle

  26. 2009
  27. Bis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential.

    Nilsson, J., Eva Degerman, Haukka, M., Lisensky, G. C., Garribba, E., Yoshikawa, Y., Sakurai, H., Enyedy, E. A., Kiss, T., Esbak, H., Rehder, D. & Ebbe Nordlander, 2009, In : Dalton Transactions. 38, p. 7902-7911

    Research output: Contribution to journalArticle

  28. Cell-cell communication between adipocytes and pancreatic beta-cells in acoustically levitated droplets

    Santesson, S., Eva Degerman, Rorsman, P., Johansson, T., Lemos, S. & Staffan Nilsson, 2009, In : Integrative Biology. 1, 10, p. 595-601

    Research output: Contribution to journalArticle

  29. Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the beta(3)-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes

    Ahmad, F., Lindh, R., Tang, Y., Ruishalme, I., Ost, A., Sahachartsiri, B., Stralfors, P., Eva Degerman & Manganiello, V. C., 2009, In : Biochemical Journal. 424, p. 399-410

    Research output: Contribution to journalArticle

  30. Phosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism.

    Karin Berger, Lindh, R., Nils Wierup, Zmuda-Trzebiatowska, E., Andreas Lindqvist, Manganiello, V. C. & Eva Degerman, 2009, In : PLoS ONE. 4, 3, e4671

    Research output: Contribution to journalArticle

  31. Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis.

    Omar, B., Zmuda-Trzebiatowska, E., Manganiello, V., Olga Göransson & Eva Degerman, 2009, In : Cellular Signalling. 21, p. 760-766

    Research output: Contribution to journalArticle

  32. 2008
  33. Macroporous gel particles as robust macroporous matrices for cell immobilization

    Plieva, F., Oknianska, A., Eva Degerman & Bo Mattiasson, 2008, In : Biotechnology Journal. 3, 3, p. 410-417

    Research output: Contribution to journalArticle

  34. 2007
  35. beta-cell PDE3B regulates Ca(2+)-stimulated exocytosis of insulin.

    Jones, H., Nils Wierup, Vikman, J., Manganiello, V. C., Eva Degerman, Lena Eliasson & Stenson, L., 2007, In : Cellular Signalling. 19, Feb 12, p. 1505-1513

    Research output: Contribution to journalArticle

  36. Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB

    Ahmad, F., Lindh, R., Tang, Y., Weston, M., Eva Degerman & Manganiello, V. C., 2007, In : Biochemical Journal. 404, p. 257-268

    Research output: Contribution to journalArticle

  37. Long-term regulation of cyclic nucleotide phosphodiesterase type 3B and 4 in 3T3-L1 adipocytes.

    Oknianska, A., Zmuda-Trzebiatowska, E., Manganiello, V. & Eva Degerman, 2007, In : Biochemical and Biophysical Research Communications. 353, 4, p. 1080-1085

    Research output: Contribution to journalArticle

  38. Multisite phosphorylation of adipocyte and hepatocyte phosphodiesterase 3B.

    Lindh, R., Ahmad, F., Resjö, S., Peter James, Yang, J. S., Fales, H. M., Manganiello, V. & Eva Degerman, 2007, In : Biochimica et Biophysica Acta: Molecular Cell Research. 1773, 4, p. 584-592

    Research output: Contribution to journalArticle

  39. Novel mechanisms of the regulation of Protein kinase B in adipocytes; implications for Protein kinase A, Epac, Phosphodiesterases 3 and 4.

    Zmuda-Trzebiatowska, E., Manganiello, V. & Eva Degerman, 2007, In : Cellular Signalling. 19, 1, p. 81-86

    Research output: Contribution to journalArticle

  40. Perilipin and adipophilin expression in lipid loaded macrophages

    Persson, J., Eva Degerman, Jan Nilsson & Lindholm, M., 2007, In : Biochemical and Biophysical Research Communications. 363, 4, p. 1020-1026

    Research output: Contribution to journalArticle

  41. Re-discovering PDE3 inhibitors - New opportunities for a long neglected target

    Thompson, P. E., Manganiello, V. & Eva Degerman, 2007, In : Current Topics in Medicinal Chemistry. 7, 4, p. 421-436

    Research output: Contribution to journalReview article

  42. Regulation of cyclic nucleotide phosphodiesterase 3 (PDE3)

    Manganiello, VC., Ahmad, F., Choi, YH., Tang, Y., Lindh, R., ZmudaTrzebiatowska, E., Walz, H., Karin Berger, Sheng, W., Liu, H., Hockman, S., Park, S., Stenson, L. & Eva Degerman, 2007, Mie University Press.

    Research output: Book/ReportBook

  43. 2006
  44. Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice

    Choi, Y. H., Park, S., Hockman, S., Zmuda-Trzebiatowska, E., Svennelid, F., Haluzik, M., Gavrilova, O., Ahmad, F., Pepin, L., Napolitano, M., Taira, M., Sundler, F., Stenson, L., Eva Degerman & Manganiello, V. C., 2006, In : Journal of Clinical Investigation. 116, 12, p. 3240-3251

    Research output: Contribution to journalArticle

  45. Chemical derivatization of phosphoserine and phosphothreonine containing peptides to increase sensitivity for MALDI-based analysis and for selectivity of MS/MS analysis

    Arrigoni, G., Resjö, S., Fredrik Levander, Nilsson, R., Eva Degerman, Quadroni, M., Pinna, LA. & Peter James, 2006, In : Proteomics. 6, 3, p. 757-766

    Research output: Contribution to journalArticle

  46. Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.

    Jones, H., Härndahl, L., Nils Wierup, Zmuda-Trzebiatowska, E., Svennelid, F., Manganiello, V. C., Ploug, T., Sundler, F., Eva Degerman, Bo Ahrén & Holst, L. S., 2006, In : Journal of Endocrinology. 189, 3, p. 629-641

    Research output: Contribution to journalArticle

  47. Importance of cAMP-response element-binding protein in regulation of expression of the murine cyclic nucleotide phosphodiesterase 3B (Pde3b) gene in differentiating 3T3-L1 preadipocytes

    Liu, H., Tang, J. R., Choi, Y. H., Napolitano, M., Hockman, S., Taira, M., Eva Degerman & Manganiello, V. C., 2006, In : Journal of Biological Chemistry. 281, 30, p. 21096-21113

    Research output: Contribution to journalArticle

  48. Novel supermacroporous dextran gels

    Plieva, F., Oknianska, A., Eva Degerman, Galaev, I. & Bo Mattiasson, 2006, In : Journal of Biomaterials Science. Polymer Edition. 17, 10, p. 1075-1092

    Research output: Contribution to journalArticle

  49. Plasma membrane cyclic nucleotide phosphodiesterase 3B (PDE3B) is associated with caveolae in primary adipocytes.

    Nilsson, R., Ahmad, F., Karl Swärd, Ulrika Axling, Weston, M., Manganiello, V. & Eva Degerman, 2006, In : Cellular Signalling. 18, 2006 Feb 24, p. 1713-1721

    Research output: Contribution to journalArticle

  50. Role of PDE3B in insulin-induced glucose uptake, GLUT-4 translocation and lipogenesis in primary rat adipocytes.

    Zmuda-Trzebiatowska, E., Oknianska, A., Manganiello, V. & Eva Degerman, 2006, In : Cellular Signalling. 18, 3, p. 382-390

    Research output: Contribution to journalArticle

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