Gunnar Juliusson

Professor, Specialist Physician

Research areas and keywords

UKÄ subject classification

  • Cancer and Oncology

Keywords

  • Hematologic cancers, genetics, epidemiology

Research

Molecular characterization and epidemiology of acute myeloid leukemia (AML)in adults. Swedish patients with AML have been prospectively reported to the nationalBlood Cancer Registry since 1997, which now contains data on diagnosticresults, management and outcome for more than 6000 patients(http://www.cancercentrum.se/samverkan/cancerdiagnoser/blod-lymfom-myelom/akut-myeloisk-leukemi-aml-inkl-akut-oklassificerad-leukemi-aul/kvalitetsregister/), and represents an unique database with real worlddata, especially for the majority of patients that are older (median age 71years). Since 2014 all new AML patients in our department have a bonemarrow sampled for next generation sequencing including whole exome andRNA sequencing. A comparison with constitutional DNA from skin biopsy isperformed to assess leukemia-specific abnormalities. Follow-up samples toassess minimal residual disease and clonal changes at subsequent diseasedevelopment is also collected and analyzed. Rare clinicopathologicalassociations are being identified, and clinical associations defined, in closecollaboration between laboratory and clinical department.

Highlighted research outputs

Gunnar Juliusson, Antunovic, P., Derolf, A., Lehmann, S., Mollgard, L., Stockelberg, D., Tidefelt, U., Wahlin, A. & Hoglund, M. 2009 In : Blood. 113, 18, p. 4179-4187

Research output: Contribution to journalArticle

Lazarevic, V., Hörstedt, A., Johansson, E., Antunovic, P., Billström, R., Derolf, A., Hulegårdh, E., Lehmann, S., Möllgård, L., Nilsson, C., Peterson, S., Stockelberg, D., Uggla, B., Wennström, L., Wahlin, A., Höglund, M. & Gunnar Juliusson 2014 In : Blood Cancer Journal. 4, Feb 28, p. e188

Research output: Contribution to journalArticle

Hulegardh, E., Nilsson, C., Lazarevic, V., Garelius, H., Antunovic, P., Rangert Derolf, A., Mollgard, L., Uggla, B., Wennstrom, L., Wahlin, A., Hoglund, M., Gunnar Juliusson, Stockelberg, D. & Lehmann, S. 2015 In : American Journal of Hematology. 90, 3, p. 208-214

Research output: Contribution to journalArticle

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