Kristian Pietras

Professor, Directly Appointed
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  1. 2018
  2. Consensus guidelines for the use and interpretation of angiogenesis assays

    Nowak-Sliwinska, P. , Alitalo, K. , Allen, E. , Anisimov, A. , Aplin, A. C. , Auerbach, R. , Augustin, H. G. , Bates, D. O. , van Beijnum, J. R. , Bender, R. H. F. , Bergers, G. , Bikfalvi, A. , Bischoff, J. , Böck, B. C. , Brooks, P. C. , Bussolino, F. , Cakir, B. , Carmeliet, P. , Castranova, D. , Cimpean, A. M. & 66 others Cleaver, O., Coukos, G., Davis, G. E., de Palma, M., Dimberg, A., Dings, R. P. M., Djonov, V., Dudley, A. C., Dufton, N. P., Fendt, S. M., Ferrara, N., Fruttiger, M., Fukumura, D., Ghesquière, B., Gong, Y., Griffin, R. J., Harris, A. L., Hughes, C. C. W., Hultgren, N. W., Iruela-Arispe, M. L., Irving, M., Jain, R. K., Kalluri, R., Kalucka, J., Kerbel, R. S., Kitajewski, J., Klaassen, I., Kleinmann, H. K., Koolwijk, P., Kuczynski, E., Kwak, B. R., Marien, K., Melero-Martin, J. M., Munn, L. L., Nicosia, R. F., Noel, A., Nurro, J., Olsson, A. K., Petrova, T. V., Kristian Pietras, Pili, R., Pollard, J. W., Post, M. J., Quax, P. H. A., Rabinovich, G. A., Raica, M., Randi, A. M., Ribatti, D., Ruegg, C., Schlingemann, R. O., Schulte-Merker, S., Smith, L. E. H., Song, J. W., Stacker, S. A., Stalin, J., Stratman, A. N., van de Velde, M., van Hinsbergh, V. W. M., Vermeulen, P. B., Waltenberger, J., Weinstein, B. M., Xin, H., Yetkin-Arik, B., Yla-Herttuala, S., Yoder, M. C. & Griffioen, A. W., 2018 Aug, In : Angiogenesis. 21, 3, p. 425-532

    Research output: Contribution to journalArticle

  3. Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling

    Roswall, P. , Bocci, M. , Bartoschek, M. , Li, H. , Kristiansen, G. , Jansson, S. , Lehn, S. , Sjölund, J. , Reid, S. , Larsson, C. , Eriksson, P. , Anderberg, C. , Cortez, E. , Saal, L. H. , Orsmark-Pietras, C. , Cordero, E. , Haller, B. K. , Häkkinen, J. , Burvenich, I. J. G. , Lim, E. & 7 others Orimo, A., Mattias Höglund, Lisa Rydén, Moch, H., Scott, A. M., Eriksson, U. & Kristian Pietras, 2018 Mar 12, In : Nature Medicine. 24, p. 463–473

    Research output: Contribution to journalArticle

  4. 2016
  5. Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML

    O Lindblad, Cordero, E., Puissant, A., Macaulay, L., Ramos, A., Kabir, N. N., J Sun, J Vallon-Christersson, Haraldsson, K., Hemann, M. T., Åke Borg, F Levander, Stegmaier, K., K Pietras, L Rönnstrand & J U Kazi, 2016 Sep 29, In : Oncogene. 35, 39, p. 5119-5131 13 p.

    Research output: Contribution to journalArticle

  6. Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function

    De Vinuesa, A. G., Matteo Bocci, Kristian Pietras & Dijke, P. T., 2016 Aug 15, In : Biochemical Society Transactions. 44, 4, p. 1142-1149 8 p.

    Research output: Contribution to journalArticle

  7. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I

    Dass, R. A., Sarshad, A. A., Carson, B. B., Feenstra, J. M., Kaur, A., Obrdlik, A., Parks, M. M., Prakash, V., Love, D. K., Kristian Pietras, Serra, R., Blanchard, S. C., Percipalle, P., Brown, A. M. C. & Vincent, C. T., 2016 Aug 1, In : PLoS Genetics. 12, 8, e1006217

    Research output: Contribution to journalArticle

  8. VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

    Li, X., Padhan, N., Sjöström, E. O., Roche, F. P., Testini, C., Honkura, N., Sáinz-Jaspeado, M., Gordon, E., Bentley, K., Philippides, A., Tolmachev, V., Dejana, E., Stan, R. V., Vestweber, D., Ballmer-Hofer, K., Betsholtz, C., Kristian Pietras, Jansson, L. & Claesson-Welsh, L., 2016 Mar 23, In : Nature Communications. 7, 11017

    Research output: Contribution to journalArticle

  9. Cartilage oligomeric matrix protein contributes to the development and metastasis of breast cancer

    E Englund, M Bartoschek, Reitsma, B., Jacobsson, L., Escudero-Esparza, A., Orimo, A., K Leandersson, C Hagerling, A Aspberg, Storm, P., Okroj, M., H Mulder, K Jirström, K Pietras & A M Blom, 2016, In : Oncogene. 35, 43, p. 5585-5596 12 p.

    Research output: Contribution to journalArticle

  10. Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

    Escudero-Esparza, A., Michael Bartoschek, Chrysostomi Gialeli, Okroj, M., Owen, S., Karin Jirström, Orimo, A., Jiang, W. G., Kristian Pietras & Anna M. Blom, 2016, In : Oncotarget. 7, 47, p. 76920-76933 14 p.

    Research output: Contribution to journalArticle

  11. Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling

    Eleftheriou, N. M., Jonas Sjölund, Matteo Bocci, Cortez, E., Lee, S. J., Cunha, S. I. & Kristian Pietras, 2016, In : Oncotarget. 7, 51, p. 84314-84325 12 p.

    Research output: Contribution to journalArticle

  12. Editorial: Novel targets and targeting technologies to modulate tumor microenvironment

    Prakash, J. (ed.) & Kristian Pietras (ed.), 2016, In : Frontiers in Oncology. 6, MAY, 121

    Research output: Contribution to journalSpecial Issue (editor)

  13. Expression of GADS enhances FLT3-induced mitogenic signaling.

    Rohit A. Chougule, Cordero, E., Sausan A. Moharram, Kristian Pietras, Lars Rönnstrand & Julhash U. Kazi, 2016, In : Oncotarget. 7, 12, p. 14112-14124

    Research output: Contribution to journalArticle

  14. Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD.

    Cortez, E., Gladh, H., Sebastian Braun, Matteo Bocci, Cordero, E., Björkström, N. K., Miyazaki, H., Michael, I. P., Eriksson, U., Folestad, E. & Kristian Pietras, 2016, In : Proceedings of the National Academy of Sciences. 113, 7, p. E864-E873

    Research output: Contribution to journalArticle

  15. 2015
  16. Decoding breast cancer tissue-stroma interactions using species-specific sequencing.

    Chivukula, I. V., Ramsköld, D., Storvall, H., Anderberg, C., Jin, S., Mamaeva, V., Sahlgren, C., Kristian Pietras, Sandberg, R. & Lendahl, U., 2015, In : Breast Cancer Research. 17, 109

    Research output: Contribution to journalArticle

  17. Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer.

    Cunha, S. I., Matteo Bocci, Lövrot, J., Eleftheriou, N., Roswall, P., Cordero, E., Lindström, L., Michael Bartoschek, Haller, B. K., Pearsall, R. S., Mulivor, A. W., Kumar, R., Christer Larsson, Bergh, J. & Kristian Pietras, 2015, In : Cancer Research. 75, 12, p. 2445-2456

    Research output: Contribution to journalArticle

  18. Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium.

    Niaudet, C. , Hofmann, J. J. , Mäe, M. A. , Jung, B. , Gaengel, K. , Vanlandewijck, M. , Ekvärn, E. , Salvado, M. D. , Mehlem, A. , Al Sayegh, S. , He, L. , Lebouvier, T. , Castro-Freire, M. , Katayama, K. , Hultenby, K. , Moessinger, C. , Tannenberg, P. , Cunha, S. , Pietras, K. , Laviña, B. & 3 others Hong, J., Berg, T. & Betsholtz, C., 2015, In : PLoS ONE. 10, 9, e0137949

    Research output: Contribution to journalArticle

  19. Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma

    Johnson, J. R., Folestad, E., Rowley, J. E., Noll, E. M., Walker, S. A., Lloyd, C. M., Rankin, S. M., Kristian Pietras, Eriksson, U. & Fuxe, J., 2015, In : American Journal of Physiology: Lung Cellular and Molecular Physiology. 308, 7, p. L658-L671

    Research output: Contribution to journalArticle

  20. 2014
  21. Functional subsets of mesenchymal cell types in the tumor microenvironment.

    Cortez, E., Roswall, P. & Kristian Pietras, 2014, In : Seminars in Cancer Biology. 25, Jan 7, p. 3-9

    Research output: Contribution to journalReview article

  22. Molecular biology of neuroendocrine tumors: from pathways to biomarkers and targets

    Capdevila, J., Meeker, A., Garcia-Carbonero, R., Kristian Pietras, Astudillo, A., Casanovas, O. & Scarpa, A., 2014, In : Cancer Metastasis Review. 33, 1, p. 345-351

    Research output: Contribution to journalReview article

  23. Novel Nano-Sized MR Contrast Agent Mediates Strong Tumor Contrast Enhancement in an Oncogene-Driven Breast Cancer Model.

    Eriksson, P-O., Aaltonen, E., Petoral, R., Lauritzson, P., Miyazaki, H., Kristian Pietras, Sven Månsson, Hansson, L., Peter Leander & Axelsson, O., 2014, In : PLoS ONE. 9, 10, e107762

    Research output: Contribution to journalArticle

  24. Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer.

    Femel, J., Huijbers, E. J. M., Saupe, F., Cedervall, J., Zhang, L., Roswall, P., Larsson, E., Olofsson, H., Kristian Pietras, Dimberg, A., Hellman, L. & Olsson, A-K., 2014, In : Oncotarget. 5, 23, p. 12418-12427

    Research output: Contribution to journalArticle

  25. 2013
  26. Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression

    Yoshimatsu, Y., Lee, Y. G., Akatsu, Y., Taguchi, L., Suzuki, H. I., Cunha, S. I., Maruyama, K., Suzuki, Y., Yamazaki, T., Katsura, A., Oh, S. P., Zimmers, T. A., Lee, S-J., Kristian Pietras, Koh, G. Y., Miyazono, K. & Watabe, T., 2013, In : Proceedings of the National Academy of Sciences. 110, 47, p. 18940-18945

    Research output: Contribution to journalArticle

  27. Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

    Anderberg, C., Cunha, S. I., Zhai, Z., Cortez, E., Pardali, E., Johnson, J. R., Franco, M., Paez-Ribes, M., Cordiner, R., Fuxe, J., Johansson, B. R., Goumans, M-J., Casanovas, O., ten Dijke, P., Arthur, H. M. & Kristian Pietras, 2013, In : Journal of Experimental Medicine. 210, 3, p. 563-579

    Research output: Contribution to journalArticle

  28. Distinct Effects of Ligand-Induced PDGFR alpha and PDGFR beta Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments

    Ehnman, M., Missiaglia, E., Folestad, E., Selfe, J., Strell, C., Thway, K., Brodin, B., Kristian Pietras, Shipley, J., Ostman, A. & Eriksson, U., 2013, In : Cancer Research. 73, 7, p. 2139-2149

    Research output: Contribution to journalArticle

  29. Fibroblasts as architects of cancer pathogenesis

    Marsh, T., Kristian Pietras & McAllister, S. S., 2013, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1832, 7, p. 1070-1078

    Research output: Contribution to journalReview article

  30. Introduction to tumor-stroma interactions

    Ostman, A. & Kristian Pietras, 2013, In : Experimental Cell Research. 319, 11, p. 1595-1595

    Research output: Contribution to journalDebate/Note/Editorial

  31. MiR-155-mediated loss of C/EBP beta shifts the TGF-beta response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer

    Johansson, J., Berg, T., Kurzejamska, E., Pang, M-F., Tabor, V., Jansson, M., Roswall, P., Kristian Pietras, Sund, M., Religa, P. & Fuxe, J., 2013, In : Oncogene. 32, 50, p. 5614-5624

    Research output: Contribution to journalArticle