Lars EdvinssonSenior Professor, DMSGI, MD, Specialist , Specialist
Research areas and keywords
UKÄ subject classification
- Medical and Health Sciences
- Clinical Medicine
Professor Edvinsson is leading expert in the field of (1) cerebral circulation and (2) migraine. He is world recognized for his work on vascular innervation and receptor regulation. His extensive research has been a major contributor to what is known about the roles of the cerebral vasculature in health and diseases such as stroke and primary headaches. He has written the major textbook in the field; Cerebral Blood Flow & Metabolism (1993 Raven Press, 2002 Lippincott Williams Wilkins). In the field of headache he is now a president of The International Headache society. Recently, his groundbreaking work on the sensory system has resulted in new medicine being introduced small molecular CGRP-blockers for acute attacks and antibodies towards CGRP or CGRP-receptors as prophylaxis chronic migraine.
Method Expertise: Immunohistochemistry, qPCR, Western blot, molecular biology of cell signaling, mRNA arrays, proteomics, cell and organ cultures, animal models for acute stroke and acute myocardial infarcts, pharmacology and treatment methods, string myography and perfusion myography for receptor and functional studies of isolated blood vessels.
Recent research outputs
Research output: Contribution to journal › Review article
Research output: Contribution to journal › Article