Mattias Brofelth

Doctoral Student, MSc

Research areas and keywords

Keywords

  • scFv antibodies, antibody microarrays

Research

As a member of the Affinity Proteomics team headed by Professor Christer Wingren, I am focused on technology development of the Antibody Microarray platform. In brief this involves protein engineering and incorporation of unnatural amino acids by site directed mutagenesis, antibody production and multiplex microarray analysis. The long-term goals are global protein expression profiling of serum samples as well as development of focused clinical tools for better diagnosis and treatment of patients with for example cancer or autoimmune diseases. 

Recent research outputs

Mattias Brofelth, Städe, L. W., Anna Isinger Ekstrand, Petersson Edfeldt, L., Kovačič, R., Nielsen, T. T., Larsen, K. L., Duroux, L. & Christer Wingren 2017 Aug In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1865, 8, p. 985-996 12 p.

Research output: Contribution to journalArticle

Petersson, L., Städe, L. W., Mattias Brofelth, Gärtner, S., Fors, E., Sandgren, M., Vallkil, J., Olsson, N., Larsen, K. L., Carl Borrebaeck, Duroux, L. & Christer Wingren 2014 In : Biochimica et Biophysica Acta. 1844, 12, p. 2164-2173

Research output: Contribution to journalArticle

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