Ola Hansson

Researcher, PI

Research areas and keywords

UKÄ subject classification

  • Physiology
  • Endocrinology and Diabetes

Keywords

  • Skeletal muscle, Functional genomics, Exercise Physiology, Metabolism

Research

Ola Hansson. PhD. Associate professor (Docent) of functional genomics at Lund University and head of the research unit Diabetes and Endocrinology, Malmö, Sweden. Main research interest is to understand how genetic variation influences skeletal muscle function and whole-body metabolism - implications primarily for human health, but also for fundamental evolutionary questions. The overarching goal is to tailor, for the individual, the most beneficial exercise program to counteract genetic predisposition to metabolic disease and type 2 diabetes. We use translational approaches and regularly conduct focused intervention studies in humans, including skeletal muscle biopsies. From the biopsies, muscle stem cells (satellite cells) are isolated and later used for preclinical measurements. In our projects we combine physiological measurements like VO2MAX, muscular strength and glucose tolerance with preclinical, e.g. RNA and ChIP sequencing, fibre typing, gene knock down and exon skipping.

Highlighted research outputs

McGawley, K., Juudas, E., Kazior, Z., Ström, K., Blomstrand, E., Ola Hansson & Holmberg, H. C., 2017 Jun 13, In : Frontiers in Physiology. 8, JUN, 413

Research output: Contribution to journalArticle

Willems, S. M. , Wright, D. J. , Day, F. R. , Trajanoska, K. , Joshi, P. K. , Morris, J. A. , Matteini, A. M. , Garton, F. C. , Grarup, N. , Oskolkov, N. , Thalamuthu, A. , Mangino, M. , Liu, J. , Demirkan, A. , Lek, M. , Xu, L. , Wang, G. , Oldmeadow, C. , Gaulton, K. J. , Lotta, L. A. & 31 others Miyamoto-Mikami, E., Rivas, M. A., White, T., Loh, P. R., Aadahl, M., Amin, N., Attia, J. R., Austin, K., Benyamin, B., Brage, S., Cheng, Y. C., Ciȩszczyk, P., Derave, W., Karl Fredrik Eriksson, Eynon, N., Linneberg, A., Lucia, A., Massidda, M., Mitchell, B. D., Miyachi, M., Murakami, H., Padmanabhan, S., Pandey, A., Papadimitriou, I., Rajpal, D. K., Sale, C., Lindgren, C. M., Paul W. Franks, Ola Hansson, Ingvarsson, T. & GEFOS Anytype of Fracture Consortium, 2017 Jul 12, In : Nature Communications. 8, 16015

Research output: Contribution to journalArticle

L Shcherbina, A Edlund, J L S Esguerra, Abels, M., Zhou, Y., Ottosson-Laakso, E., C B Wollheim, O Hansson, L Eliasson & N Wierup, 2017, In : Molecular and Cellular Endocrinology. 447, p. 52-60

Research output: Contribution to journalArticle

Su, J., Carl Ekman, Nikolay Oskolkov, Lahti, L., Ström, K., Brazma, A., Leif Groop, Rung, J. & Ola Hansson, 2015, In : Skeletal Muscle. 5, 35

Research output: Contribution to journalArticle

Carl Ekman, Targ Elgzyri, Ström, K., Almgren, P., Parikh, H., Dekker Nitert, M., Tina Rönn, Koivula, F., Charlotte Ling, Åsa Tornberg, Per Wollmer, Karl-Fredrik Eriksson, Leif Groop & Ola Hansson, 2015, In : Journal of Applied Physiology. 119, 9, p. 953-960

Research output: Contribution to journalArticle

Bozek, K., Wei, Y., Yan, Z., Liu, X., Xiong, J., Sugimoto, M., Tomita, M., Pääbo, S., Pieszek, R., Sherwood, C. C., Hof, P. R., Ely, J. J., Steinhauser, D., Willmitzer, L., Bangsbo, J., Ola Hansson, Call, J., Giavalisco, P. & Khaitovich, P., 2014, In : PLoS Biology. 12, 5, e1001871

Research output: Contribution to journalArticle

Keildson, S. , Fadista, J. , Ladenvall, C. , Hedman, A. K. , Elgzyri, T. , Small, K. S. , Grundberg, E. , Nica, A. C. , Glass, D. , Richards, J. B. , Barrett, A. , Nisbet, J. , Zheng, H-F. , Rönn, T. , Ström, K. , Eriksson, K-F. , Prokopenko, I. , Spector, T. D. , Dermitzakis, E. T. , Deloukas, P. & 6 others McCarthy, M. I., Rung, J., Leif Groop, Paul Franks, Lindgren, C. M. & Ola Hansson, 2014, In : Diabetes. 63, 3, p. 1154-1165

Research output: Contribution to journalArticle

Claussnitzer, M. , Dankel, S. N. , Klocke, B. , Grallert, H. , Glunk, V. , Berulava, T. , Lee, H. , Oskolkov, N. , Fadista, J. , Ehlers, K. , Wahl, S. , Hoffmann, C. , Qian, K. , Rönn, T. , Riess, H. , Müller-Nurasyid, M. , Bretschneider, N. , Schroeder, T. , Skurk, T. , Horsthemke, B. & 17 others Spieler, D., Klingenspor, M., Seifert, M., Kern, M. J., Mejhert, N., Dahlman, I., Ola Hansson, Hauck, S. M., Blüher, M., Arner, P., Leif Groop, Illig, T., Suhre, K., Hsu, Y-H., Mellgren, G., Hauner, H. & Laumen, H., 2014, In : Cell. 156, 1-2, p. 343-358

Research output: Contribution to journalArticle

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