Olle Melander

Professor, consultant
More filtering options
  1. 2019
  2. A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

    Ahluwalia, T. S. , Schulz, C. A. , Waage, J. , Skaaby, T. , Sandholm, N. , van Zuydam, N. , Charmet, R. , Bork-Jensen, J. , Almgren, P. , Thuesen, B. H. , Bedin, M. , Brandslund, I. , Christensen, C. K. , Linneberg, A. , Ahlqvist, E. , Groop, P. H. , Hadjadj, S. , Tregouet, D. A. , Jørgensen, M. E. , Grarup, N. & 9 others Pedersen, O., Simons, M., Leif Groop, Marju Orho-Melander, McCarthy, M. I., Olle Melander, Rossing, P., Kilpeläinen, T. O. & Hansen, T., 2019 Feb, In : Diabetologia. 62, 2, p. 292-305

    Research output: Contribution to journalArticle

  3. A genetic risk score for hypertension is associated with risk of thoracic aortic aneurysm

    Tagetti, A., Bonafini, S., T. Ohlsson, G. Engström, Almgren, P., Minuz, P., G. Smith, O. Melander & C. Fava, 2019 Jan 18, In : Journal of Human Hypertension.

    Research output: Contribution to journalArticle

  4. Modulation of lung cancer cell plasticity and heterogeneity with the restoration of cisplatin sensitivity by neurotensin antibody

    Wu, Z., Fournel, L., Stadler, N., Liu, J., Boullier, A., Hoyeau, N., Fléjou, J. F., Duchatelle, V., Djebrani-Oussedik, N., Agopiantz, M., Ségal-Bendirdjian, E., Gompel, A., Alifano, M., Olle Melander, Trédaniel, J. & Forgez, P., 2019, In : Cancer Letters. 444, p. 147-161 15 p.

    Research output: Contribution to journalArticle

  5. Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

    International Consortium for Blood Pressure, Giri, A., Almgren, P., Olle Melander, Hung, A. M. & Edwards, T. L., 2019, In : Nature Genetics. 51, 1, p. 51-62 12 p.

    Research output: Contribution to journalArticle

  6. 2018
  7. Genome-wide analysis yields new loci associating with aortic valve stenosis

    Helgadottir, A. , Thorleifsson, G. , Gretarsdottir, S. , Stefansson, O. A. , Tragante, V. , Thorolfsdottir, R. B. , Jonsdottir, I. , Bjornsson, T. , Steinthorsdottir, V. , Verweij, N. , Nielsen, J. B. , Zhou, W. , Folkersen, L. , Martinsson, A. , Heydarpour, M. , Prakash, S. , Oskarsson, G. , Gudbjartsson, T. , Geirsson, A. , Olafsson, I. & 26 others Sigurdsson, E. L., Almgren, P., Olle Melander, Franco-Cereceda, A., Hamsten, A., Fritsche, L., Lin, M., Yang, B., Hornsby, W., Guo, D., Brummett, C. M., Abecasis, G., Mathis, M., Milewicz, D., Body, S. C., Eriksson, P., Willer, C. J., Hveem, K., Newton-Cheh, C., J. Gustav Smith, Danielsen, R., Thorgeirsson, G., Thorsteinsdottir, U., Gudbjartsson, D. F., Holm, H. & Stefansson, K., 2018 Dec 1, In : Nature Communications. 9, 1, 987

    Research output: Contribution to journalArticle

  8. Prognostic significance of noncardiac syncope in the general population: A systematic review and meta-analysis

    Fabrizio Ricci, Sutton, R., Palermi, S., Tana, C., Renda, G., Gallina, S., Olle Melander, De Caterina, R. & Artur Fedorowski, 2018 Dec, In : Journal of Cardiovascular Electrophysiology. 29, 12, p. 1641-1647

    Research output: Contribution to journalArticle

  9. Cardiovascular biomarkers predict fragility fractures in older adults

    Madeleine Johansson, Fabrizio Ricci, Di Martino, G., Cecilia Rogmark, Sutton, R., Viktor Hamrefors, Olle Melander & Artur Fedorowski, 2018 Oct 15, In : Heart. 6 p.

    Research output: Contribution to journalArticle

  10. Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality

    C. Fernandez, Rysä, J., Almgren, P., J. Nilsson, G. Engström, M. Orho-Melander, Ruskoaho, H. & O. Melander, 2018 Oct 1, In : Journal of Internal Medicine. 284, 4, p. 377-387 11 p.

    Research output: Contribution to journalArticle

  11. Multi-ethnic genome-wide association study for atrial fibrillation

    Roselli, C. , Chaffin, M. D. , Weng, L. C. , Aeschbacher, S. , Ahlberg, G. , Albert, C. M. , Almgren, P. , Alonso, A. , Anderson, C. D. , Aragam, K. G. , Arking, D. E. , Barnard, J. , Bartz, T. M. , Benjamin, E. J. , Bihlmeyer, N. A. , Bis, J. C. , Bloom, H. L. , Boerwinkle, E. , Bottinger, E. B. , Brody, J. A. & 33 others Calkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y. D. I., Choi, E. K., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Dörr, M., Dudink, E. A., Dudley, S. C., Gustafsson, S., Lindgren, C. M., Olle Melander, Peter Nilsson, Marju Orho-Melander, Lubitz, S. A., Lunetta, K. L. & Ellinor, P. T., 2018 Sep, In : Nature Genetics. 50, 9, p. 1225-1233

    Research output: Contribution to journalArticle

  12. A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

    van Zuydam, N. R., Emma Ahlqvist, Ladenvall, C., Almgren, P., Christina-Alexandra Schulz, Marju Orho-Melander, Olle Melander, Valeriya Lyssenko, Tuomi, T., Leif C Groop, McCarthy, M. I., Finnish Diabetic Nephropathy Study (FinnDiane), Hong Kong Diabetes Registry Theme-based Research Scheme Project Group, GENIE (Genetics of Nepropathy an International Effort) Consortium, Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group, SUMMIT Consortium & Jasmina Kravic, 2018 Jul, In : Diabetes. 67, 7, p. 1414-1427

    Research output: Contribution to journalArticle

  13. Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

    Gusarova, V. , O'Dushlaine, C. , Teslovich, T. M. , Benotti, P. N. , Mirshahi, T. , Gottesman, O. , Van Hout, C. V. , Murray, M. F. , Mahajan, A. , Nielsen, J. B. , Fritsche, L. , Wulff, A. B. , Gudbjartsson, D. F. , Sjögren, M. , Emdin, C. A. , Scott, R. A. , Lee, W-J. , Small, A. , Kwee, L. C. , Dwivedi, O. P. & 61 others Rashmi B Prasad, Bruse, S., Lopez, A. E., Penn, J., Marcketta, A., Leader, J. B., Still, C. D., Kirchner, H. L., Mirshahi, U. L., Wardeh, A. H., Hartle, C. M., Habegger, L., Fetterolf, S. N., Tusie-Luna, T., Morris, A. P., Holm, H., Steinthorsdottir, V., Sulem, P., Thorsteinsdottir, U., Rotter, J. I., Chuang, L-M., Damrauer, S., Birtwell, D., Brummett, C. M., Khera, A. V., Natarajan, P., Marju Orho-Melander, Flannick, J., Lotta, L. A., Willer, C. J., Holmen, O. L., Ritchie, M. D., Ledbetter, D. H., Murphy, A. J., Borecki, I. B., Reid, J. G., Overton, J. D., Ola Hansson, Leif Groop, Shah, S., Kraus, W. E., Rader, D. J., Ida Chen, Y-D., Hveem, K., Wareham, N. J., Kathiresan, S., Olle Melander, Stefansson, K., Nordestgaard, B. G., Tybjaerg-Hansen, A., Abecasis, G. R., Altshuler, D., Florez, J. C., Boehnke, M., McCarthy, M., Yancopoulos, G. D., Carey, D. J., Shuldiner, A. R., Baras, A., Dewey, F. E. & Gromada, J., 2018 Jun 13, In : Nature Communications. 9, p. 1-11 2252

    Research output: Contribution to journalArticle

  14. A genome-wide association study of IgM antibody against phosphorylcholine: Shared genetics and phenotypic relationship to chronic lymphocytic leukemia

    Chen, X. , Gustafsson, S. , Whitington, T. , Borné, Y. , Lorentzen, E. , Sun, J. , Almgren, P. , Su, J. , Karlsson, R. , Song, J. , Lu, Y. , Zhan, Y. , Hägg, S. , Svensson, P. , Smedby, K. E. , Slager, S. L. , Ingelsson, E. , Lindgren, C. M. , Morris, A. P. , Melander, O. & 9 others Karlsson, T., de Faire, U., Caidahl, K., Gunnar Engström, Lind, L., Karlsson, M. C. I., Pedersen, N. L., Frostegård, J. & Magnusson, P. K. E., 2018 May 15, In : Human Molecular Genetics. 27, 10, p. 1809-1818 10 p.

    Research output: Contribution to journalArticle

  15. Proneurotensin Predicts Cardiovascular Disease in an Elderly Population

    Ayesha Fawad, Bergmann, A., Struck, J., Peter M. Nilsson, Marju Orho-Melander & Olle Melander, 2018 May 1, In : Journal of Clinical Endocrinology and Metabolism. 103, 5, p. 1940-1947 8 p.

    Research output: Contribution to journalArticle

  16. Novel subgroups of adult-onset diabetes and their association with outcomes: A data-driven cluster analysis of six variables

    Ahlqvist, E. , Storm, P. , Käräjämäki, A. , Martinell, M. , Dorkhan, M. , Carlsson, A. , Vikman, P. , Prasad, R. B. , Aly, D. M. , Almgren, P. , Wessman, Y. , Shaat, N. , Spégel, P. , Mulder, H. , Lindholm, E. , Melander, O. , Hansson, O. , Malmqvist, U. , Lernmark, Å. , Lahti, K. & 4 others Forsén, T., Tuomi, T., Anders H. Rosengren & Leif Groop, 2018 May, In : The Lancet Diabetes and Endocrinology. 6, 5, p. 361-369

    Research output: Contribution to journalArticle

  17. Neurotensin is a lipid-induced gastrointestinal peptide associated with visceral adipose tissue inflammation in obesity

    Barchetta, I., Cimini, F. A., Capoccia, D., Bertoccini, L., Ceccarelli, V., Chiappetta, C., Leonetti, F., Di Cristofano, C., Silecchia, G., Marju Orho-Melander, Olle Melander & Cavallo, M. G., 2018 Apr 23, In : Nutrients. 10, 4, 526

    Research output: Contribution to journalArticle

  18. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

    Wood, A. M. , Kaptoge, S. , Butterworth, A. , Willeit, P. , Warnakula, S. , Bolton, T. , Paige, E. , Paul, D. S. , Sweeting, M. , Burgess, S. , Bell, S. , Astle, W. , Stevens, D. , Koulman, A. , Selmer, R. M. , Verschuren, W. M. M. , Sato, S. , Njølstad, I. , Woodward, M. , Salomaa, V. & 31 others Nordestgaard, B. G., Yeap, B. B., Fletcher, A., Olle Melander, Kuller, L. H., Balkau, B., Marmot, M., Koenig, W., Casiglia, E., Cooper, C., Arndt, V., Franco, O. H., Wennberg, P., Gallacher, J., de la Cámara, A. G., Völzke, H., Dahm, C. C., Dale, C. E., Bergmann, M., Crespo, C., van der Schouw, Y. T., Kaaks, R., Simons, L. A., Lagiou, P., Schoufour, J. D., Boer, J. M. A., Key, T. J., Rodriguez, B., Moreno-Iribas, C., Davidson, K. W. & Emerging Risk Factors Collaboration, 2018 Apr 14, In : The Lancet. 391, 10129, p. 1513-1523 11 p.

    Research output: Contribution to journalArticle

  19. Role of blood lipids in the development of ischemic stroke and its subtypes: A mendelian randomization study

    George Hindy, Gunnar Engström, Larsson, S. C., Traylor, M., Markus, H. S., Olle Melander & Marju Orho-Melander, 2018 Apr 1, In : Stroke. 49, 4, p. 820-827 8 p.

    Research output: Contribution to journalArticle

  20. Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

    Malik, R., Chauhan, G., Traylor, M., Sargurupremraj, M., Okada, Y., Mishra, A., Almgren, P., Olle Melander, Gunnar Engström, Arne Lindgren, Hossein Delavaran, Andreea Ilinca, Bo Norrving & MEGASTROKE Consortium, 2018 Apr, In : Nature Genetics. 50, 4, p. 524-537

    Research output: Contribution to journalArticle

  21. Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

    Li, Y. , Xiao, X. , Han, Y. , Gorlova, O. , Qian, D. , Leighl, N. , Johansen, J. S. , Barnett, M. , Chen, C. , Goodman, G. , Cox, A. , Taylor, F. , Woll, P. , Wichmann, H. E. , Manz, J. , Muley, T. , Risch, A. , Rosenberger, A. , Arnold, S. M. , Haura, E. B. & 56 others Bolca, C., Holcatova, I., Janout, V., Kontic, M., Lissowska, J., Mukeria, A., Ognjanovic, S., Orlowski, T. M., Scelo, G., Swiatkowska, B., Zaridze, D., Bakke, P., Skaug, V., Zienolddiny, S., Duell, E. J., Butler, L. M., Houlston, R., Artigas, M. S., Grankvist, K., Johansson, M., Shepherd, F. A., Marcus, M. W., Hans Brunnström, Jonas Manjer, Olle Melander, Muller, D. C., Overvad, K., Trichopoulou, A., Tumino, R., Liu, G., Bojesen, S. E., Wu, X., Marchand, L. L., Albanes, D., Bickeböller, H., Aldrich, M. C., Bush, W. S., Tardon, A., Rennert, G., Dawn Teare, M., Field, J. K., Kiemeney, L. A., Lazarus, P., Haugen, A., Lam, S., Schabath, M. B., Andrew, A. S., Bertazzi, P. A., Pesatori, A. C., Christiani, D. C., Caporaso, N., Johansson, M., McKay, J. D., Brennan, P., Hung, R. J. & Amos, C. I., 2018 Mar 8, In : Carcinogenesis. 39, 3, p. 336-346 11 p.

    Research output: Contribution to journalArticle

  22. Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension

    Madeleine Johansson, Fabrizio Ricci, Aung, N., Sutton, R., Olle Melander & Artur Fedorowski, 2018 Mar, In : Hypertension. 71, 3, p. 465-472 8 p.

    Research output: Contribution to journalArticle

  23. Interaction of dietary and genetic factors influencing body iron status and risk of type 2 diabetes within the EPIC-InterAct study

    Meidtner, K. , Podmore, C. , Kröger, J. , Van Der Schouw, Y. T. , Bendinelli, B. , Agnoli, C. , Arriola, L. , Barricarte, A. , Boeing, H. , Cross, A. J. , Dow, C. , Ekblom, K. , Fagherazzi, G. , Franks, P. W. , Gunter, M. J. , Huerta, J. M. , Jakszyn, P. , Jenab, M. , Katzke, V. A. , Key, T. J. & 22 others Khaw, K. T., Kühn, T., Kyrø, C., Mancini, F. R., Olle Melander, Peter M. Nilsson, Overvad, K., Palli, D., Panico, S., Ramón Quirós, J., Rodríguez-Barranco, M., Sacerdote, C., Sluijs, I., Stepien, M., Tjonneland, A., Tumino, R., Forouhi, N. G., Sharp, S. J., Langenberg, C., Schulze, M. B., Riboli, E. & Wareham, N. J., 2018 Feb 1, In : Diabetes Care. 41, 2, p. 277-285 9 p.

    Research output: Contribution to journalArticle

  24. Separate and combined associations of obesity and metabolic health with coronary heart disease: A pan-European case-cohort analysis

    Lassale, C. , Tzoulaki, I. , Moons, K. G. M. , Sweeting, M. , Boer, J. , Johnson, L. , Huerta, J. M. , Agnoli, C. , Freisling, H. , Weiderpass, E. , Wennberg, P. , Van Der A, D. L. , Arriola, L. , Benetou, V. , Boeing, H. , Bonnet, F. , Colorado-Yohar, S. M. , Engström, G. , Eriksen, A. K. , Ferrari, P. & 29 others Grioni, S., Johansson, M., Kaaks, R., Katsoulis, M., Katzke, V., Key, T. J., Matullo, G., Olle Melander, Molina-Portillo, E., Moreno-Iribas, C., Norberg, M., Overvad, K., Panico, S., Quiros, J. R., Saieva, C., Skeie, G., Steffen, A., Stepien, M., Tjønneland, A., Trichopoulou, A., Tumino, R., Van Der Schouw, Y. T., Verschuren, W. M. M., Langenberg, C., Di Angelantonio, E., Riboli, E., Wareham, N. J., Danesh, J. & Butterworth, A. S., 2018 Feb 1, In : European Heart Journal. 39, 5, p. 397-406 10 p.

    Research output: Contribution to journalArticle

  25. Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study

    Ricci, C. , Wood, A. , Muller, D. , Gunter, M. J. , Agudo, A. , Boeing, H. , Van Der Schouw, Y. T. , Warnakula, S. , Saieva, C. , Spijkerman, A. , Sluijs, I. , Tjønneland, A. , Kyrø, C. , Weiderpass, E. , Kühn, T. , Kaaks, R. , Sánchez, M. J. , Panico, S. , Agnoli, C. , Palli, D. & 30 others Tumino, R., Gunnar Engström, Olle Melander, Bonnet, F., Boer, J. M. A., Key, T. J., Travis, R. C., Overvad, K., Verschuren, W. M. M., Quirós, J. R., Trichopoulou, A., Papatesta, E. M., Peppa, E., Iribas, C. M., Gavrila, D., Forslund, A. S., Jansson, J. H., Matullo, G., Arriola, L., Freisling, H., Lassale, C., Tzoulaki, I., Sharp, S. J., Forouhi, N. G., Langenberg, C., Saracci, R., Sweeting, M., Brennan, P., Butterworth, A. S. & Riboli, E., 2018 Jan 1, In : BMJ (Online). 361, k934

    Research output: Contribution to journalArticle

  26. A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor

    Stanne, T. M., Olsson, M., Lorentzen, E., Pedersen, A., Gummesson, A., Gils, A., Jood, K., Gunnar Engström, Olle Melander, Declerck, P. J. & Jern, C., 2018, In : Thrombosis and Haemostasis. 118, 2, p. 298-308

    Research output: Contribution to journalArticle

  27. A multilocus genetic risk score is associated with arterial stiffness in hypertensive patients: The CARE NORTH study

    Polonis, K., Hoffmann, M., Szyndler, A., Wolf, J., Nowak, R., Becari, C., Laurent, S., Boutouyrie, P., Olle Melander & Narkiewicz, K., 2018, In : Journal of Hypertension. 36, 9, p. 1882-1888 7 p.

    Research output: Contribution to journalArticle

  28. Association between systemic leptin and neurotensin concentration in adult individuals with and without type 2 diabetes mellitus

    Barchetta, I., Ciccarelli, G., Cimini, F. A., Ceccarelli, V., M. Orho-Melander, O. Melander & Cavallo, M. G., 2018, In : Journal of Endocrinological Investigation. 41, 10, p. 1159-1163

    Research output: Contribution to journalArticle

  29. Blood Lead Levels and Decreased Kidney Function in a Population-Based Cohort

    Harari, F., Sallsten, G., Anders Christensson, Marinka Petkovic, Bo Hedblad, Forsgard, N., Olle Melander, Peter M. Nilsson, Borné, Y., Gunnar Engström & Barregard, L., 2018, In : American Journal of Kidney Diseases. 72, 3, p. 381-389

    Research output: Contribution to journalArticle

  30. Cardiovascular risk after hospitalisation for unexplained syncope and orthostatic hypotension

    Ekrem Yasa, Ricci, F., Martin Magnusson, Sutton, R., Gallina, S., De Caterina, R., Olle Melander & Artur Fedorowski, 2018, In : Heart. 104, 6, p. 487-493

    Research output: Contribution to journalArticle

Previous 1 2 3 4 5 6 7 8 ...10 Next