Oskar Hansson

Professor, Specialist Physician

Research areas and keywords

UKÄ subject classification

  • Medical and Health Sciences

Keywords

  • Alzheimer's, Parkinson's, Biomarker, MRI, PET

Research

Résumé

Oskar Hansson has during the last ten years performed internationally recognized and outstanding clinical and translational research focusing on the earliest phase of Alzheimer's and Parkinson’s diseases. His results have been implemented into modern diagnostic criteria as well as optimized design of clinical trials. For instance, his studies are part of the basis for the newly proposed diagnostic criteria for Alzheimer’s disease and were a significant part of the scientific foundation for the European Medicines Agencies (EMA) recommendation to use cerebrospinal fluid biomarkers for early detection of Alzheimer’s disease in clinical trials. Importantly, his landmark study on Alzheimer biomarkers (beta-amyloid and tau) from 2006 (The Lancet Neurology; cited  > 860 times) has been instrumental for the implementation of these biomarkers in the clinical work-up of Alzheimer's disease in Sweden and internationally. His continued research is internationally widely recognized (cited >7000, H-index 41; Scopus) and his work on biomarkers has led to over 130 original research articles. One of Oskar Hansson's biomarker papers (Buchhave et al 2012) was considered one of the most important international findings in Alzheimer research in 2012 (Weiner. Nat Rev Neurol. 2013; 9: 65). Besides having collaborations with world-leading national and international research groups he also collaborates with many of the important pharmaceutical industries, including Hoffman-La Roche, GE Healthcare, Jansen, Eisai, Avid Radiopharmaceutical, which has resulted in important scientific findings. Oskar Hansson is part of and in leading positions in several distinguished scientific networks, including the strategic network in neuroscience at LU (MultiPark), a Linnaeus environment (Bagadilico, LU), Swedish Parkinson Academy (SUS), and Swedish Brain Power (national network). Since 2007, Oskar Hansson has funded all of his research through significant independent grants, totaling over 70 million SEK, from e.g. the European Research Council (ERC; Starting Grant), the Swedish Research Council andthe Marianne and Marcus Wallenberg foundation. In the last two years he has received several prestigious awards for his independent research, including Wallenberg Clinical Fellow from the Marianne and Marcus Wallenberg foundation, the Inga Sandeborg’s research award from the Swedish Society of Medicine, the Eric K. Fernström award at Lund University from the Fernström foundation and the Bengt Falck's award in Neuroscience from the medical faculty at LU.

 

1.         Higher education degree

2005. University Medical Degree (Medical Doctor).

1998. Lund Graduate School of Biomedical Research

 

2.         Doctoral Degree

2001. Neurobiology. “Neuronal cell death and restoration in the basal ganglia: implications for Huntington’s and Parkinson’s diseases”. Supervisor: Professor Patrik Brundin (Lund University).

 

3.         Post doctoral positions

2005 – 2007: Independent research at Clinical Memory Research Unit, Lund University.

2007 – 2008: Independent research at Department of Neurology, Skåne University Hospital.

 

4.         Qualification as Associate Professor (Docent level)

2008.   Subject: Neuroscience.

 

5.         Specialist certification

2012    Specialist in Neurology.

2013    Senior resident (överläkare) in Neurology.

 

6.         Recent positions

2014 to today: Senior lecturer and neurologist (“kombinationstjänst lektor/överläkare”) at both Lund University and Skåne University Hospital.

2015 to today:  Vice coordinator of Multipark; the strategic research area of Neuroscience at Lund University (http://www.med.lu.se/multipark).

2012-2104: Senior neurologist (överläkare) in Neurology (25%), Memory Clinic, Skåne University Hospital.

2011-2014:  Senior researcher at Lund University (75%). I have a six-year senior research position funded by the Swedish Research Council until 2017.

2011-2012:  Assistant coordinator of Multipark.

 

7.         Previous positions

2007-2012     Resident in Neurology, Department of Neurology, Malmö, Skåne University Hospital.

2005-2006     Clinical internship (AT), Skåne University Hospital.

2005               Junior physician, Neuropsychiatric clinic, Malmö, Skåne University Hospital.

1998-2001     Graduate student, Wallenberg Neuroscience Center, Lund University.

 

8a.       People awarded doctorates, for which the applicant is/has been main supervisor:

Peder Buchhave, dissertation 1 April 2011.

Joakim Hertze, dissertation in 8 April 2016.

 

I am currently main supervisor for:

1) Sara Hall (planned dissertation 2017);

2) Yulia Surova (planned dissertation 2017);

3) Maurits Johansson (planned dissertation 2019).

4) Mattis Jalakas (planned dissertation 2020).

5) Philp Insel (planned dissertation 2020).

6) Emelie Andersson (planned dissertation 2021).

 

8b.       People awarded doctorates, for which the applicant is/has been co-supervisor:

1) Sebastian Palmqvist, dissertation 6 June 2011;

2) Erik Stomrud, dissertation 12 December 2009;

3) Fredrik Boström, dissertation 12 September 2009;

4) Åsa Wallin, dissertation 12 May 2008.

5) Fredrik Åhlander (planned dissertation 2018).

6) Eva Bergström Mandl (planned dissertation 2019).

7) Anna-Märta Gustavsson (planned dissertation 2019).

8) Daniel Svärd (planned dissertation 2019).

9) Tomas Olsson (planned dissertation 2020).

10) Isak Martinsson (planned dissertation 2021).

11) Claes Håkansson (planned dissertation 2021).

 

8c.       Postdoctoral researchers who is/has been supervised by the applicant

1) Sebastian Palmqvist (2011-today);

2) Erik Stomrud (2011-today);

3) Olof Strandberg (2013-today)

4) Shorena Janelidze (2013-today)

5) Olof Lindberg (2013-today)

6) Ruben Smith (2014-today)

7) Michael Schöll 2015-2016

8) Martin Schain (2015-2016)

9) Andreas Hahn (2015-2016)

10) Christopher Dunning (2015-2015)

11) Daniel Lindqvist (2011-2015)

12) Edina Silajdzic (2011-2014)

13) Fredrik Boström (2011-2012)

 

9.         Special grounds for deduction of time after awarded doctoral degree

2007-2012:      Resident in Neurology 50-70%, Skåne University Hospital.

2008:               Four months of parental leave.

2005-2006:      Clinical internship (AT) 100%, Skåne University Hospital.

2001-2004:      Medical school (semester 6-11).

 

10a) Other research related awards and assignments

2015    Awarded Wallenberg Clinical Fellow (Marianne and Marcus Wallenberg foundation)

2015    Awarded the Eric K. Fernström award at Lund University.

2015    Awarded the Bengt Falck's award in Neuroscience.

2015    Medical expert for the Swedish National Board of Health and Welfare.

2014    Awarded with Inga Sandeborg’s research award from the Swedish Society of Medicine.

2013    Lions Research Foundation Award.

2013    Medical reviewer of the Swedish Agency for Health Technology Assessment and   Assessment of Social Services

2012    Received grant from the European Research Council (starting grant; 1 500 000 Euro).

2011    Awarded a research position (100%) for 6 years by the Swedish Research Council.

2010-today: Associate editor of Journal of Alzheimer’s Disease.

2000-today: Ad hoc reviewer for > 30 scientific journals, including Lancet Neurology, JAMA Psychiatry and Brain.

2010-today: Reviewer for Cochrane.

 

10b) Leadership

2014-today:     Elected vice coordinator of MultiPark (http://www.med.lu.se/multipark; a translational program that ranges from pre-clinical research to studies on the life situation of patients with Parkinson's disease; budget 110 billion SEK over 5 years).

2013-today:     Head of the outpatient ward of the Memory Clinic, Skåne University Hospital.

2011-today:     Elected member of the board and WP leader in the clinical part of the Linnaeus environment BAGADILICO (www.med.lu.se/bagadilico) at Lund University, 2010.

2011-today:     Included in the steering committee of Swedish Parkinson Academy (www.parkinsonakademien.se).

2011-today:     Elected member of the board of the Swedish Parkinson foundation (http://www.parkinsonfonden.se).

2011-2012:      Elected vice coordinator of MultiPark.

 

10c) Research funding

During the last decade I have received about 55 million SEK in funding for my research including grants from the European Research Council (ERC Staring Grant), the Swedish research Council and The regional agreement on medical training and clinical research (ALF) between Skåne County Council and Lund University.

 

11)       Publications

Oskar Hansson is author of 159 peer-reviewed original articles, published between 1998 and 2016. These articles have been cited more than 7000 times (h-index: 41) according to “Scopus”. When analyzed with “Google Scholar” the articles have been cited more than 9600 times (h-index: 48). The numbers of citations were determined September 2016.

Recent research outputs

Skillbäck, T., Delsing, L., Synnergren, J., Niklas Mattsson, Shorena Janelidze, Katarina Nägga, Kilander, L., Hicks, R., Wimo, A., Winblad, B., Oskar Hansson, Blennow, K., Eriksdotter, M. & Zetterberg, H. 2017 Nov 1 In : Neurobiology of Aging. 59, p. 1-9 9 p.

Research output: Contribution to journalArticle

Pereira, J. B., Westman, E., Oskar Hansson & Alzheimer's Disease Neuroimaging Initiative 2017 Oct 1 In : Neurobiology of Aging. 58, p. 14-29

Research output: Contribution to journalArticle

Shams, S., Fällmar, D., Schwarz, S. T., Wahlund, L. O., D. Van Westen, O. Hansson, Larsson, E. M. & Haller, S. 2017 Sep 1 In : American Journal of Neuroradiology. 38, 9, p. 1737-1741 5 p.

Research output: Contribution to journalArticle

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