Anesthesia in Closed Loop

Project: ResearchClinical research

Research areas and keywords

UKÄ subject classification

  • Control Engineering
  • Anesthesiology and Intensive Care

Description

Computer controlled, or automatic, drug delivery is the process of administering a therapeutic regime to a patient with computer assistance for calculation of optimal dose and delivery schedules. Computer control can improve drug therapy by reducing drug usage and costs, by permitting health care staff to work more efficiently and to provide better standard of care, by allowing the safe use of drugs that are difficult to administer, and by compensation for human failings with computer strengths, such as unlimited attention span and patience, and capacity for quick, accurate and redundant calculation.

Our goal is to develop an automatic control system for anesthesia and to demonstrate its efficacy, safety and benefits in an operating room. Although closed-loop anesthesia has previously been proposed and tested, it has yet to have a significant impact on clinical practice. Recent developments in sensing for anesthesia have opened new possibilities for closing the loop. Our research will focus on the deployment of new sensors optimized for controlled drug delivery, robust control methodology and extensive clinical validation.

Clinical partner in the project is the Department of Anesthesia at the British Columbia Children's Hospital (BCCH), Vancouver, Canada, where patient modeling data is collected and clinical trials of the control system are conducted.
StatusFinished
Effective start/end date2011/01/012012/12/31

Collaborative partners

Participants

Related research output

Kristian Soltesz, van Heusden, K., Hast, M., Ansermino, J. M. & Dumont, G. A. 2016 Proceedings of the 2016 American Control Conference. Institute of Electrical and Electronics Engineers Inc., p. 4877-4882

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

Kristian Soltesz & Mercader, P. 2016 2016 International Conference on Systems in Medicine and Biology (ICSMB). IEEE--Institute of Electrical and Electronics Engineers Inc., p. 140-143

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

van Heusden, K., Dumont, G. A., Kristian Soltesz, Petersen, C. L., Umedaly, A., West, N. & Ansermino, J. M. 2014 In : IEEE Transactions on Control Systems Technology. 22, 2, p. 491-501

Research output: Contribution to journalArticle

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Related activities

Kristian Soltesz (Peer reviewer)
2018

Activity: Publication peer-review and editorial workJournal/Manuscript peer review

Kristian Soltesz (Peer reviewer)
2018

Activity: Publication peer-review and editorial workJournal/Manuscript peer review

Kristian Soltesz (Reviewer)
2018

Activity: Consultancy, expert advice and membershipsWork for advisory/policy/evaluation group or panel (public/government/UN/EU etc)

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