Multiparametric mapping of the brain at 7T using gradient echoes

Project: ResearchInternational collaboration

Research areas and keywords

Keywords

  • MRI, brain, multiparameter mapping

Description

The versatility and high effiecacy of the 3D spoiled gradient-echo sequence is employed for multi-parametric mapping of the brain at 7T. By variable flip angles (VFA) are used to map the transverse relaxation rate R1=1/T1 and proton density, but also magnetisation transfer (MT) if selective MT-pulses are applied off-resonance prior to excitation. Acquiring multiple gradient echoes yields the effective transverse relaxation rate R2*=1/T2*, besides an increase in SNR in VFA experiments. The signal phase is exploited for mapping the local B0 field, which in turn is modeled by quantitative distribution of susceptibility (qSM).
Short titleMPM at 7T
StatusActive
Effective start/end date2016/11/012020/11/01

Collaborative partners

  • Lund University (lead)
  • Danish Research Center for Magnetic Resonance, Hvidovre Hospital
  • Max Planck Institute for Human Cognitive and Brain Sciences

Participants

Related research output

Balteau, E., Tabelow, K., Ashburner, J., Callaghan, M., Draganski, B., Gunther Helms, Kherif, F., Leutritz, T., Lutti, A., Philips, C., Reimer, E., Ruthotto, L., Seif, M., Weiskopf, N., Ziegler, G. & Mohammadi, S., 2018 Jul 31, Berlin: Weierstraß Institute for Applied Analysis and Stochastics, 35 p.

Research output: Working paper

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