Structural brain MRI and SPECT of common marmosets using clinical scanners

Project: ResearchCollaboration with industry

Research areas and keywords

UKÄ subject classification

  • Medical and Health Sciences

Keywords

  • MRI, SPECT, translational research,common marmoset, neurodeneration, EAE

Description

The common marmoset monkey is increasingly used in translational research as a model for neurodegenerative diseases, e.g. multiple sclerosis or Parkinsons disease (Encepharm, Göttingen). Structural brain MRI protocols were implemented on clinical SIEMENS Trio MR systems to obtain anatomical correlates of disease development. Emphasis was put on minimizing stress, free-breathing under sedation and speed. SPECT imaging was performed on a 3-headed gamma camera (Picker Prism 3000) equipped with pyramidal collimators and 6-pinholes aperture plates (HiSPECT, SciVis, Göttingen).
Short titleMarmoset MRI
StatusFinished
Effective start/end date2012/01/012015/12/31

Collaborative partners

  • Lund University
  • University Medical Center Göttingen (lead)
  • Encepharm, Göttingen (Project partner)

Participants

  • Gunther Helms - MR Physics (Researcher)
  • Schlumbohm, Christina - LocalizedString(id=52311697, text={sv_SE=Encepharm, Göttingen, en_GB=Encepharm, Göttingen}) (Researcher)
  • Garea Rodriguez, Enrique - LocalizedString(id=52311697, text={sv_SE=Encepharm, Göttingen, en_GB=Encepharm, Göttingen}) (Researcher)
  • Stassart, Ruth - LocalizedString(id=52314224, text={sv_SE=University Medical Center Göttingen, en_GB=University Medical Center Göttingen}) (Researcher)
  • Fuchs, Eberhard - LocalizedString(id=52318883, text={sv_SE=German Primate Center, en_GB=German Primate Center}) (PI)

Related research output

Stassart, R. M., Gunther Helms, Garea-Rodriguez, E., Nessler, S., Hayardeny, L., Wegner, C., Schlumbohm, C., Fuchs, E. & Brück, W., 2016, In : Brain Pathology. 26, 4, p. 452-464

Research output: Contribution to journalArticle

Garea-Rodríguez, E., Eesmaa, A., Lindholm, P. K., Schlumbohm, C., König, J., Meller, B., Krieglstein, K., Gunther Helms, Saarma, M. & Fuchs, E., 2016, In : PLoS ONE. 11, 2, p. 1-21

Research output: Contribution to journalArticle

Gunther Helms, Schlumbohm, C., Garea-Rodriguez, E., Dechent, P. & Fuchs, E., 2016, In : Journal of Medical Primatology. 45, 6, p. 290-296 7 p.

Research output: Contribution to journalArticle

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