A comparison of the alpha-L-fucosidase activities of human liver and serum

Research output: Contribution to journalArticle

Abstract

Human liver alpha-L-fucosidase (alpha-L-fucoside fucohydrolase, EC 3.2.1.51) has been separated into four components by chromatography on Sephadex G-150 or DEAE-cellulose. These components differ in their relative stability to heat and acid treatment, and their response to neuraminidase. The serum enzyme was devoid of high molecular weight activity and probably contained more sialic acid residues than the corresponding enzyme from liver. All the liver components tested were able to liberate fucose from 2'-fucosyllactose but not fucose from other oligosaccharides.

Details

Authors
  • Alan Chester
  • B Hultberg
  • S Sjöblad
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Biological Sciences
Original languageEnglish
Pages (from-to)147-155
JournalBiochimica et Biophysica Acta
Volume485
Issue number1
StatePublished - 1977
Peer-reviewedYes