An automated image-collection system for crystallization experiments using SBS standard microplates

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Abstract

As part of a structural genomics platform in a university laboratory, a low-cost in-house-developed automated imaging system for SBS microplate experiments has been designed and constructed. The imaging system can scan a microplate in 2-6 min for a 96-well plate depending on the plate layout and scanning options. A web-based crystallization database system has been developed, enabling users to follow their crystallization experiments from a web browser. As the system has been designed and built by students and crystallographers using commercially available parts, this report is aimed to serve as a do-it-yourself example for laboratory robotics.

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Keywords

  • Automation, Crystallization, Data Collection, Databases, Factual, Diagnostic Imaging, Genomics, Microarray Analysis, Robotics
Original languageEnglish
Pages (from-to)119-25
Number of pages7
JournalActa Crystallographica. Section D: Biological Crystallography
Volume63
Issue numberPt 2
StatePublished - 2007 Feb
Peer-reviewedYes