An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells.

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Abstract

Aberrant DNA methylation is frequently observed in breast cancer. However, the relationship between methylation patterns and the heterogeneity of breast cancer has not been comprehensively characterized.

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  • Cancer and Oncology
Original languageEnglish
Article number27
JournalBreast Cancer Research
Volume18
Issue number1
StatePublished - 2016
Publication categoryResearch
Peer-reviewedYes