Complex avoidance behavior and its neurochemical regulation in the land snail Cepea numerals

Research output: Contribution to journalArticle

Abstract

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1. In hot plate experiments, the pulmonate land snail Cepaea nemoralis displays a biphasic passive/active avoidance behaviour composed of retraction and subsequent searching mediated by antagonistic muscular systems. The switch, between the behaviours, is under neuronal control.
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2. Leu- and met-enkephalin, as well as FMRFamide-antiserum, attenuated the retraction response and potentiated the searching behaviour. Opposite effects were achieved by injection of antisera to the enkephalins.
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3. Both retraction and searching behaviours were potentiated by 5-HT. Methysergide antagonized the effects of the enkephalins on the searching behaviour.
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4. We conclude that endogenous opioids act antagonistic to FMRFamide in the neuronally controlled switch between passive and active avoidance behaviour.

Details

Authors
Organisations
External organisations
  • Russian Academy of Sciences
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Zoology

Keywords

  • Land snail, opioids, FMRFamide, serotonin, avoidance behaviour
Original languageEnglish
Pages (from-to)773-777
JournalGeneral Pharmacology
Volume26
StatePublished - 1995
Peer-reviewedYes