Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control

Research output: Contribution to journalArticle

Abstract

To identify genetic variants associated with diabetic retinopathy (DR), we performed a large multiethnic genome-wide association study. Discovery included eight European cohorts (n = 3,246) and seven African American cohorts (n = 2,611). We meta-analyzed across cohorts using inverse-variance weighting, with and without liability threshold modeling of glycemic control and duration of diabetes. Variants with a P value

Details

Authors
Organisations
External organisations
  • Harvard University
  • Boston University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Endocrinology and Diabetes
  • Medical Genetics
Original languageEnglish
Pages (from-to)441-456
Number of pages16
JournalDiabetes
Volume68
Issue number2
StatePublished - 2019
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

Export Date: 28 January 2019