Safety of device closure of secundum atrial septal defects in children-does the weight at time of procedure matter?
Research output: Contribution to journal › Published meeting abstract
Background: Transcatheter closure of secundum atrial septal defect (ASD) is nowadays the main treatment option in many centers worldwide. In symptomatic infants or in those with certain comorbidities, there is a need for early intervention. Limited data are available about the procedural safety in infants below 15 kg of weight. Methods: Retrospective review of all patients referred to our center for ASD closure by device between January 1998 and November 2014. Major complications included death, cardiac or respiratory arrest, stroke, device embolization and erosion, need for emergency surgery or recatheterisation due to other procedure-related complications, significant pleural/pericardial effusion requiring intervention, persistent arrhythmia or intraprocedural arrhythmia requiring cardioversion/ resuscitation, postprocedural significant valvular insufficiency or pulmonary vein obstruction, need for transfusion due to significant bleeding, and permanent vein thrombosis. Minor complications included transient arrhythmia, significant access site hematoma, transient vein thrombosis, transient limb paresthesis, and development of postprocedural infection occurring within 48 hours. Data were retrieved from the hospital's database and from the Swedish Registry for Congenital Heart Disease (Swedcon). Results: In total, 244 cases with age15 kg, there were 6 major (one death related to device erosion in a 17-year female with 26 mm ASD and absent retroaortic rim, surgical removal of device, arrhythmia requiring conversion in 2 patients, and need of transfusion) and 4 minor complications (transient arrhythmia). Conclusion: Transcatheter ASD closure appears to be safe and highly successful even in small infants. (Table Presented).
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Number of pages||1|
|Journal||Cardiology in the Young|
|Issue number||Suppl. 1|
|State||Published - 2015 May 1|