Description
High stress levels are directly and indirectly associated with an increased risk of cardiovascular disease, and sleep duration is a novel risk factor for cardiovascular disease where both short and long sleep duration are associated with cardiovascular outcomes. Studies suggest that individual susceptibility may be an important factor for the association between psychological/behavioral factors and health outcomes.Individual susceptibility to health outcomes secondary to high psychological stress or short and long sleep duration may in turn be dependent on genetic and biological factors. The aim of this PhD project is to investigate, using a large general population cohort (the Malmö Diet and Cancer Study (MDC)), the associations between the respective exposures of psychological stress and sleep duration and coronary heart disease. We will further investigate if any found association is modified by individual susceptibility to disease, i.e. genetic or biological factors. The results of the study will increase the current knowledge on the importance of psychological/behavioral factors on health outcomes and possibly define specific population subgroups which will benefit from behavioral interventions.
Period | 2016 Jun 7 → … |
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Examinee/Supervised person | Thomas Svensson |
Examination/Supervision held at |
Documents & Links
Related content
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Research output
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A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death
Research output: Contribution to journal › Article › peer-review
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Incident diabetes mellitus may explain the association between sleep duration and incident coronary heart disease
Research output: Contribution to journal › Article › peer-review
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Association of Sleep Duration with All- And Major-Cause Mortality among Adults in Japan, China, Singapore, and Korea
Research output: Contribution to journal › Article › peer-review
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Plasma concentration of Caspase-8 is associated with short sleep duration and the risk of incident diabetes mellitus
Research output: Contribution to journal › Article › peer-review