Activity: Examination and supervision › Supervision
Description
A) analyse the effect of Menadione and Vitamin C (potential chemotherpay agenst for treatment of glioblastoma multiforme) on the antigen processing machinery and hence its possible effect on subsequent immunotherapy
B) find (I) peptides that break the interaction of tapasin and MHC class I, and (II) peptides that allow a prolonged association of tapasin and MHC class I