Description
Cardiovascular disease, heart failure and preeclampsia are major health problems worldwide. Thus, a search for unifying modifiable risk factors is key for effective prevention. Vasopressin, also known as antidiuretic hormone, is commonly known as an important operator in the salt and water regulation of the body but has several other physiological effects. For example, the hormone is involved in glucose metabolism by mediating insulin and glucagon release, glycogenolysis and gluconeogenesis and secretion of adrenocorticotropic hormone. Vasopressin, measured as the stable vasopressin marker copeptin, has shown to predict new onset type 2 diabetes independently of all other diabetes risk factors as well as beeing an independent risk factor for cardiovascular disease. Furthermore, it was recently shown that elevated vasopressin measured as copeptin in early pregnancy can predict both gestational diabetes and preeclampsia. This project aims at investigating the possible roll of vasopressin in the development of heart failure, atherosclerosis, arterial stiffness and preeclampsia.Period | 2019 Mar 1 → … |
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Examinee/Supervised person | Fredrika Schill |
Examination/Supervision held at |