Mass spectrometry proteomics platform for proteoform analysis

Infrastructure

    Infrastructure Details

    Acronym

    Proteoforms@LU

    Description

    The platform provides expertise in proteome analysis, including possible affinity enrichment of low-abundance proteoforms, and strategies for detection of specific protein variants (proteoforms). Mass spectrometry is used for the identification and quantification of proteins.

    Equipment and resources

    Mass spectrometer QExactive HF-X, Nano liquid chromatography systems (EASY nLC 1200, EvoSep One). Protocols for enrichments of modified proteins and peptides.

    Services provided

    Mass spectrometry analysis of proteins. Protocols for sample processing and enrichment of proteins.

    Management of the infrastructure

    Managed by a steering committee a the Department of Immunotechnology.

    Subject classification (UKÄ)

    • Engineering and Technology

    Type of infrastructure

    • Equipment
    • Services