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Unit profile

The research group conducts research on the clinical course and risk of developing lung disease, liver disease and other diseases in alpha-1-antitrypsin deficiency (AAT deficiency). Some of the research is based on the Swedish National Register of individuals with severe alpha-1 antitrypsin deficiency (AAT). The research group also follows a unique cohort of individuals with severe and moderate AAT deficiency identified through neonatal screening between 1972-194. The cohort is the only group of deficient individuals in the world, identified at birth and followed up regularly throughout life.


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