Research output per year
Research output per year
Unit profile
Description
Kajsa Paulsson is Research Group Leader for this research groupResearch
We use molecular genetic techniques such as next-generation sequencing and SNP array analysis to identify and characterize acquired genetic aberrations in aneuploid malignancies, with a particular focus on high hyperdiploid and hypodiploid acute lymphoblastic leukemia and anaplastic thyroid cancer. Primary aim To understand how massive chromosomal gain and loss arise and affect cancer cells. Secondary aim To identify novel treatment-stratifying markers and new therapeutic targets in aneuploid malignancies.UKÄ subject classification
- Cancer and Oncology
- Hematology
Free keywords
- Leukemia
- high hyperdiploid
- anaplastic thyroid
- cancer genomics
- aneuploidy
- hypodiploidy
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Efe Aydin
- Division of Clinical Genetics - Doctoral student
- Aneuploidy in cancer - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Christel Björk
- Aneuploidy in cancer - Research project participant
- Division of Clinical Genetics - Research project participant
Person
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Larissa Moura
- Division of Clinical Genetics - Doctoral student
- Aneuploidy in cancer - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer
Aydın, E., Saus, E., Chorostecki, U. & Gabaldón, T., 2023, (E-pub ahead of print) In: IUBMB Life.Research output: Contribution to journal › Article › peer-review
Open Access -
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia
Woodward, E. L., Yang, M., Moura-Castro, L. H., van den Bos, H., Gunnarsson, R., Olsson-Arvidsson, L., Spierings, D. C. J., Castor, A., Duployez, N., Zaliova, M., Zuna, J., Johansson, B., Foijer, F. & Paulsson, K., 2023 Mar 25, In: Nature Communications. 14, 1658.Research output: Contribution to journal › Article › peer-review
Open Access -
Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations
Subramaniam, A., Sandén, C., Moura-Castro, L., Žemaitis, K., Schmiderer, L., Baudet, A., Bäckström, A., Arvidsson, E., Hultmark, S., Miharada, N., Magnusson, M., Paulsson, K., Fioretos, T. & Larsson, J., 2022, In: Haematologica. 107, 9, p. 2271-2275Research output: Contribution to journal › Letter › peer-review
Open Access
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Non-coding mutations in pediatric acute lymphoblastic leukemia
Aydin, E., Paulsson, K. & Yang, M.
2021/10/01 → 2025/10/01
Project: Dissertation
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Epigenetics - Theme, Pufendorf IAS
Forsén, S., Castor, A., Bengtsson, T., Brosberg, K., Hedlund, M., Höglund, M., Lindvall, M., Ling, C., Minssen, T., Paulsson, K., Psouni, E., Ringnér, M. & Bommenel, E.
2009/08/09 → 2010/08/10
Project: Network
Activities
- 1 Organisation of conference
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Focus on Cancer collaboration
Cecilia Jädert (Organiser), Anna-Karin Wihlborg (Invited speaker), Carina Bernardo (Organiser), Corinna Richter (Organiser), Chris Madsen (Organiser), Douglas Hanahan (Invited speaker), Åsa Dahm (Invited speaker), Göran Ahlgren (Invited speaker), Trine Grönlund (Invited speaker), Anders Bjartell (Invited speaker), Bjorn Walse (Invited speaker), Kajsa Paulsson (Session chair), Emma Niméus (Session chair), Pamela Buchwald (Session chair), Roland Andersson (Session chair), Marcus Järås (Session chair), Ana Carneiro (Session chair), Håkan Axelson (Session chair), Gottfrid Sjödahl (Session chair) & Pia Berntsson (Advisor)
2021 Feb 4Activity: Participating in or organising an event › Organisation of conference
File
Prizes and distinction
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Samfundet Folkhälsan Albert de la Chapelle Prize in Medical Genetics
Paulsson, Kajsa (Recipient), 2022
Prize: Prize (including medals and awards)
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Senior Investigator Award, Cancerfonden
Paulsson, Kajsa (Recipient), 2015
Prize: Prize (including medals and awards)