Research output per year
Research output per year
Unit profile
Research
We use molecular genetic techniques such as next-generation sequencing and SNP array analysis to identify and characterize acquired genetic aberrations in aneuploid malignancies, with a particular focus on high hyperdiploid and hypodiploid acute lymphoblastic leukemia and anaplastic thyroid cancer. Primary aim To understand how massive chromosomal gain and loss arise and affect cancer cells. Secondary aim To identify novel treatment-stratifying markers and new therapeutic targets in aneuploid malignancies.
UKÄ subject classification
- Cancer and Oncology
- Hematology
Free keywords
- Leukemia
- high hyperdiploid
- anaplastic thyroid
- cancer genomics
- aneuploidy
- hypodiploidy
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Efe Aydin
- Division of Clinical Genetics - Doctoral student
- Aneuploidy in cancer - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Christel Björk
- Aneuploidy in cancer - Research project participant
- Division of Clinical Genetics - Research project participant
Person
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Larissa Moura
- Division of Clinical Genetics - Doctoral student
- Aneuploidy in cancer - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, H., Henningsson, R., Puente-Moncada, N., Peña-Martínez, P., Sjöström, L., Ågerstam, H., Sandén, C., Rissler, M., Castor, A., Marquart, H., Modvig, S., Paulsson, K., Pronk, C. J., Schmiegelow, K., Hyrenius-Wittsten, A., Orsmark-Pietras, C., Lilljebjörn, H. & Fioretos, T., 2024 Sept 26, In: Blood. 144, 13, p. 1399-1411Research output: Contribution to journal › Article › peer-review
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A temporal developmental map separates human NK cells from noncytotoxic ILCs through clonal and single-cell analysis
Vo, D. N., Yuan, O., Kanaya, M., Telliam-Dushime, G., Li, H., Kotova, O., Caglar, E., Honnens de Lichtenberg, K., Rahman, S. H., Soneji, S., Scheding, S., Bryder, D., Malmberg, K.-J. & Sitnicka, E., 2024 Jun 11, In: Blood Advances. 8, 11, p. 2933-2951Research output: Contribution to journal › Article › peer-review
Open Access -
Postnatal origin of the chromosomal gains in older patients with high hyperdiploid acute lymphoblastic leukemia
Yang, M., Gunnarsson, R., Duployez, N., Zaliova, M., Zuna, J., Johansson, B. & Paulsson, K., 2024 Jun, In: Haematologica. 109, 6, p. 1951-1955 5 p.Research output: Contribution to journal › Letter › peer-review
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Non-coding mutations in pediatric acute lymphoblastic leukemia
Aydin, E. (Research student), Paulsson, K. (Supervisor) & Yang, M. (Assistant supervisor)
2021/10/01 → 2025/10/01
Project: Dissertation
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The role of constitutional and acquired genetic variants in hyperdiploid pediatric leukemia.
Ragnarsson, C. (Researcher)
Project: Dissertation
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Epigenetics - Theme, Pufendorf IAS
Forsén, S. (Project coordinator), Castor, A. (Researcher), Bengtsson, T. (Researcher), Brosberg, K. (Researcher), Hedlund, M. (Researcher), Höglund, M. (Researcher), Lindvall, M. (Researcher), Ling, C. (Researcher), Minssen, T. (Researcher), Paulsson, K. (Researcher), Psouni, E. (Researcher), Ringnér, M. (Researcher), Bommenel, E. (Researcher) & Lundin, S. (Researcher)
2009/08/09 → 2010/08/10
Project: Network
Activities
- 1 Organisation of conference
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Focus on Cancer collaboration
Jädert, C. (Organiser), Wihlborg, A.-K. (Invited speaker), Bernardo, C. (Organiser), Richter, C. (Organiser), Madsen, C. (Organiser), Hanahan, D. (Invited speaker), Dahm, Å. (Invited speaker), Ahlgren, G. (Invited speaker), Grönlund, T. (Invited speaker), Bjartell, A. (Invited speaker), Walse, B. (Invited speaker), Paulsson, K. (Session chair), Niméus, E. (Session chair), Buchwald, P. (Session chair), Andersson, R. (Session chair), Järås, M. (Session chair), Carneiro, A. (Session chair), Axelson, H. (Session chair), Sjödahl, G. (Session chair) & Berntsson, P. (Advisor)
2021 Feb 4Activity: Participating in or organising an event › Organisation of conference
File
Prizes and distinction
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Samfundet Folkhälsan Albert de la Chapelle Prize in Medical Genetics
Paulsson, K. (Recipient), 2022
Prize: Prize (including medals and awards)
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Senior Investigator Award, Cancerfonden
Paulsson, K. (Recipient), 2015
Prize: Prize (including medals and awards)