Cardiac Inflammation Research Group

Research output

Research output per year 2023 2023 2024 2024

• 15 Article
• 2 Letter
• 1 Debate/Note/Editorial
• 1 Doctoral Thesis (compilation)

Research output per year

Research output per year

Search results

• 2024

  Reply to “Potential confounders in linking elevated S100A8/A9 to left ventricular dysfunction in septic shock patients”

  Jakobsson, G., Andersson, H., Chew, M. & Schiopu, A., 2024 Dec, In: Critical Care. 28, 1, 9.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• The Gly82Ser polymorphism in the receptor for advanced glycation endproducts increases the risk for coronary events in the general population

  Grauen Larsen, H., Sun, J., Sjögren, M., Borné, Y., Engström, G., Nilsson, P., Orho-Melander, M., Goncalves, I., Nilsson, J., Melander, O. & Schiopu, A., 2024 Dec, In: Scientific Reports. 14, 1, 11567.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Eicosanoid Receptor 100%
  • Single-Nucleotide Polymorphism 42%
  • Blood Plasma 33%
  • Genetics 28%
  • Genetic Variability 16%

• Elevated carbohydrate antigen 125 (CA125) is associated with incident heart failure and mortality in acute coronary syndrome

  Yndigegn, T., Gu, T., Grufman, H., Erlinge, D., Mokhtari, A., Ekelund, U., Magnusson, M., Gustafsson, E., Nilsson, J., Goncalves, I. & Schiopu, A., 2024 Sept 1, (E-pub ahead of print) In: ESC Heart Failure. p. 1-10

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mortality 100%
  • Acute Coronary Syndrome 100%
  • Carbohydrate Antigen 100%
  • Patient 22%
  • Follow up 22%

• Short-term S100A8/A9 Blockade Promotes Cardiac Neovascularization after Myocardial Infarction

  Mares, R. G., Suica, V. I., Uyy, E., Boteanu, R. M., Ivan, L., Cocuz, I. G., Sabau, A. H., Yadav, V., Szabo, I. A., Cotoi, O. S., Tomut, M. E., Jakobsson, G., Simionescu, M., Antohe, F. & Schiopu, A., 2024 Jul 15, (E-pub ahead of print) In: Journal of Cardiovascular Translational Research.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients

  Didriksson, I., Lengquist, M., Spångfors, M., Leffler, M., Sievert, T., Lilja, G., Frigyesi, A., Friberg, H. & Schiopu, A., 2024 Jul 9, In: Journal of Intensive Care. 12, 1, 26.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Patient 100%
  • Mortality 100%
  • COVID-19 100%
  • Intensive Care Unit 45%
  • Association 18%

• Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction. Reply

  Yndigegn, T., Hofmann, R. & Jernberg, T., 2024 Jul, In: The New England journal of medicine. 391, 1, p. 95 1 p.

  Research output: Contribution to journal › Letter

• A study of size-selective renal elimination using a novel human model

  Sigurjonsson, J., Grubb, D., Grubb, A., Christensson, A., Öberg, C., Ederoth, P., Koul, S., Götberg, M., Yndigegn, T., Tödt, T., Viterius, B. & Bjursten, H., 2024 Apr 8, (E-pub ahead of print) In: Scandinavian Journal of Clinical & Laboratory Investigation. p. 1-6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Elimination 100%
  • Cystatin C 50%
  • Glomerular Filtration Rate 30%
  • Syndrome 20%
  • C-Peptide 10%

• Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation

  Mulholland, M., Depuydt, M. A. C., Jakobsson, G., Ljungcrantz, I., Grentzmann, A., To, F., Bengtsson, E., Jaensson Gyllenbäck, E., Grönberg, C., Rattik, S., Liberg, D., Schiopu, A., Björkbacka, H., Kuiper, J., Bot, I., Slütter, B. & Engelbertsen, D., 2024 Apr 2, (E-pub ahead of print) In: Cardiovascular Research.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atherosclerosis 100%
  • Plaque 100%
  • Development 100%
  • Inflammation 100%
  • Interleukin-1 Receptor 100%

• Special Issue “COVID-19 Coagulopathy: Advances on Pathophysiology and Therapies”

  Russu, E., Arbănaşi, E. M. & Șchiopu, A., 2024 Mar, In: International Journal of Molecular Sciences. 25, 6, 3548.

  Research output: Contribution to journal › Debate/Note/Editorial

  Open Access

• Mechanistic and therapeutic studies in cardiac inflammation

  Jakobsson, G., 2024, Lund: Lund University, Faculty of Medicine. 79 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  • Inflammation 100%
  • Sepsis 87%
  • Interleukin-1 55%
  • Neutrophil 44%
  • Pathogenesis 37%
• 2023

  Association between high-sensitivity C-reactive protein and coronary atherosclerosis in a general middle-aged population

  Cederström, S., Lundman, P., Alfredsson, J., Hagström, E., Ravn-Fischer, A., Söderberg, S., Yndigegn, T., Tornvall, P. & Jernberg, T., 2023 Dec, In: Scientific Reports. 13, 1, 12171.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronary Artery Atherosclerosis 100%
  • Detection 100%
  • Inflammation 22%
  • Systemic Inflammation 11%

• Invariant natural killer T cells and incidence of first-time coronary events: a nested case-control study

  Tomas, L., Katra, P., Badn, W., Andersson, L., Nilsson, J., Schiopu, A., Engelbertsen, D., Gonçalves, I., Bengtsson, E. & Björkbacka, H., 2023 Nov 1, In: European Heart Journal Open. 3, 6, oead094.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Incidence 100%
  • Cardiovascular Disease 100%
  • Case-Control Study 100%
  • Investigation 100%
  • Control Study 100%

• Prevalence of angina pectoris and association with coronary atherosclerosis in a general population

  Welén Schef, K., Tornvall, P., Alfredsson, J., Hagström, E., Ravn-Fischer, A., Soderberg, S., Yndigegn, T. & Jernberg, T., 2023 Oct, In: Heart. 109, 19, p. 1450-1459 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Females 100%
  • Transponder 100%
  • Hypertension 100%
  • Procedures 24%
  • Female 24%

• Long-term Safety of Revascularization Deferral Based on Instantaneous Wave-Free Ratio or Fractional Flow Reserve

  Yndigegn, T., Koul, S., Rylance, R., Berntorp, K., Mohammad, M. A., Omerovic, E., Sarno, G., Linder, R., Fröbert, O., Jensen, J., Schiopu, A., Erlinge, D. & Götberg, M., 2023 Sept 1, In: Journal of the Society for Cardiovascular Angiography and Interventions. 2, 5, 101046.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Revascularization 100%
  • Fractional Flow Reserve 100%
  • Patient 23%
  • Myocardial Infarction 15%
  • Cause of Death 7%

• Association of beta-blockers beyond 1 year after myocardial infarction and cardiovascular outcomes

  Ishak, D., Aktaa, S., Lindhagen, L., Alfredsson, J., Dondo, T. B., Held, C., Jernberg, T., Yndigegn, T., Gale, C. P. & Batra, G., 2023 Aug 1, In: Heart. 109, 15, p. 1159-1165 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myocardial Infarction 100%
  • Association 100%
  • Cardiovascular System 100%
  • Heart Infarction 100%
  • Patient 77%

• S100A8/A9 is a valuable biomarker and treatment target to detect and modulate neutrophil involvement in myocardial infarction

  Mareş, R. G., Sabău, A. H., Cocuz, I. G., Tomuţ, M. E., Szabo, I. A., Szőke, A. R., Tinca, A. C., Jakobsson, G., Cotoi, O. S. & Şchiopu, A., 2023 Apr, In: Romanian Journal of Morphology and Embryology. 64, 2, p. 151-158 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heart Infarction 100%
  • Neutrophil 100%
  • Heart Injury 25%
  • Heart Failure 12%
  • Heart Muscle Injury 12%

• Elevated soluble LOX-1 predicts risk of first-time myocardial infarction

  Schiopu, A., Björkbacka, H., Narasimhan, G., Loong, B. J., Engström, G., Melander, O., Orho-Melander, M. & Nilsson, J., 2023, In: Annals of Medicine. 55, 2, 2296552.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heart Infarction 100%
  • Malignant Neoplasm 16%
  • Incidence 16%
  • Population Study 16%
  • Enzyme-Linked Immunosorbent Assay 16%

• Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction

  Jakobsson, G., Papareddy, P., Andersson, H., Mulholland, M., Bhongir, R., Ljungcrantz, I., Engelbertsen, D., Björkbacka, H., Nilsson, J., Manea, A., Herwald, H., Ruiz-Meana, M., Rodríguez-Sinovas, A., Chew, M. & Schiopu, A., 2023, In: Critical Care. 27, p. 1-16 374.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mouse 100%
  • Systemic Inflammation 100%
  • Inflammation 100%
  • Sepsis 100%
  • Blood Plasma 75%

• Vascular smooth muscle–specific YAP/TAZ deletion triggers aneurysm development in mouse aorta

  Martínez, M. A., Ritsvall, O., Bastrup, J. A., Celik, S., Jakobsson, G., Daoud, F., Winqvist, C., Aspberg, A., Rippe, C., Maegdefessel, L., Schiopu, A., Jepps, T. A., Holmberg, J., Swärd, K. & Albinsson, S., 2023, In: JCI Insight. 8, 17, e170845.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Blood Pressure 100%
  • Aneurysm 100%
  • Aorta 100%
  • Gene 50%
  • Mouse Model 50%