Research output per year
Research output per year
Unit profile
Research
The focus of our research is to understand the molecular determinants underlying cellular reprogramming and hematopoietic specification. Cellular reprogramming can be achieved experimentally in different ways, including nuclear transfer, cell fusion or expression of transcription factors. The emergent ability to directly reprogram any human cell into desired hematopoietic cell-types is opening avenues to the discovery of new therapies for immune and blood diseases. The goals of my laboratory are a) to understand at the molecular level how hematopoietic cellular identities are specified employing cellular reprogramming and b) to use this knowledge to manipulate genes and pathways that ultimately may allow the generation of patient-specific hematopoietic cells for regenerative medicine and immunotherapy.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Abigail Altman
- Division of Molecular Medicine and Gene Therapy - Student working on a degree project
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Nejc Arh
- Division of Molecular Medicine and Gene Therapy - Doctoral student
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Ervin Ascic
- Division of Molecular Medicine and Gene Therapy - Doctoral student
- Cell Reprogramming in Hematopoiesis and Immunity - Visiting research fellow
- LUCC: Lund University Cancer Centre - Doctoral student
Person
Research output
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Transcription factor-mediated reprogramming to antigen-presenting cells
Ascic, E. & Pereira, C.-F., 2025, In: Current Opinion in Genetics & Development. 90, 102300.Research output: Contribution to journal › Review article › peer-review
Open Access -
Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses
Xiao, H., Ulmert, I., Bach, L., Huber, J., Narasimhan, H., Kurochkin, I., Chang, Y., Holst, S., Mörbe, U., Zhang, L., Schlitzer, A., Pereira, C. F., Schraml, B. U., Baumjohann, D. & Lahl, K., 2024 Dec, In: Nature Communications. 15, 1, 3554.Research output: Contribution to journal › Article › peer-review
Open Access -
Reprogramming Stars #18: Engineering Cell Fates and Preventing Disease by Repressing Unwanted Plasticity-An Interview with Dr. Moritz Mall
Mall, M., Lopes, M. & Pereira, C. F., 2024 Oct 1, In: Cellular Reprogramming. 26, 5, p. 125-131 7 p.Research output: Contribution to journal › Letter › peer-review
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Functional chemical reprogramming of cancer cells to induce antitumor immunity
Pereira, F. (PI), Fiúza Rosa, F. (Researcher) & Arh, N. (Researcher)
2024/01/01 → 2026/12/31
Project: Research
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Neoantigen Identification with Dendritic Cell Reprogramming
Pereira, F. (Researcher), Ascic, E. (Researcher), Nascimento Caiado, I. M. (Researcher), Kurochkin, I. (Researcher), Fiúza Rosa, F. (CoI), Pires, C. (CoI), Bassani, M. (CoI), Marie Svane, I. (CoI) & Greiff, L. (CoI)
European Commission - Horizon Europe
2023/01/01 → …
Project: Research
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REPROcode: a single-cell platform to define transcription factors for immune cell reprogramming
Pereira, F. (PI), Kurochkin, I. (Researcher), Altman, A. (Researcher), Nascimento Caiado, I. M. (Researcher), Pértiga Cabral, D. F. (Researcher), Nair, M. S. (Researcher), Zimmermannova, O. (Researcher), Fiúza Rosa, F. (CoI) & Pires, C. (CoI)
Cancer Research Institute (CRI)
2023/01/01 → …
Project: Research
Activities
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UniStem Day 2024: Dissemination and outreach of stem cell science
Ottosson, D. (Organiser), Magnusson, M. (Organiser), Kidnapillai, S. (Organiser), Ahlenius, H. (Organiser), Luis, A. B. (Organiser), Martinez Curiel, R. (Organiser), Laurin, K. (Organiser), Martos Salvo, P. (Organiser), Das, M. (Contributor), Wendler, M. (Contributor), Sivani, B. M. (Contributor), Ramos Passarello, G. (Contributor), Sozzi, E. (Contributor), García Garrote, M. (Contributor), Harrison Umeano, C. (Contributor), Okeke, U. C. (Contributor), Horvath, V. (Contributor), Garza, R. (Contributor), Adami, A. (Contributor), Castilla-Vallmanya, L. (Contributor), Gerdes, P. (Contributor), Pandiloski, N. (Contributor), Jin, Q. (Contributor), de Guidi, C. (Contributor), Palma Tortosa, S. (Contributor), Fritze, J. (Contributor), Jansson, L. I. (Contributor), Robles Rodriguez, L. (Contributor), Pracucci, E. (Contributor), Shen, Y.-P. (Contributor), Trovato, F. (Contributor), Tampé, J. (Contributor), Thakore, R. (Contributor), Stamouli, C.-A. (Contributor), Pinto dos Santos Vaz, C. (Contributor), Aretio, C. (Contributor), Piochon, C. (Contributor), Cepeda-Prado, E. (Contributor), de Jongh, M.-M. (Contributor), Tsalkitzidou, M. (Contributor), Bonsberger, J. (Contributor), Douse, C. (Contributor), Dorazehi, F. (Contributor), Koutounidou, S. (Contributor), Jarl, U. (Contributor), Corsi, S. (Contributor), Bruzelius, A. (Contributor), Mattsson, B. (Contributor), Hammarberg, A. (Contributor), Habekost, M. (Contributor), Prabhala, P. (Contributor), Bremborg, T. (Contributor), Nair, M. S. (Contributor), Burdeyron, P. (Contributor), Mazariegos, M. (Contributor), Björklund, M. (Contributor), Hidalgo, I. (Contributor), Hägg, A. (Invited speaker), Hammarlund, E. (Invited speaker), Mohlin, S. (Invited speaker) & Oesterle, M. (Contributor)
2024 Mar 22Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Cellular Reprogramming of Cancer Cells to Antigen-presenting Cells for Immunotherapy
Pereira, F. (Speaker)
2024Activity: Talk or presentation › Invited talk
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How we published a paper in Science
Pereira, F. (Invited speaker)
2024Activity: Talk or presentation › Invited talk
Prizes and distinction
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Novo Nordisk Distinguished Innovator Grant
Pereira, F. (Recipient), 2023
Prize: Prize (including medals and awards)
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Best PhD thesis in cancer award 2021 at Lund University
Fiúza Rosa, F. (Recipient), 2022 Jan 24
Prize: Prize (including medals and awards)