Research output per year
Research output per year
Unit profile
Description
Type 2 diabetes develops as a conspiracy between the genetic background and the environment. The interaction between genes and environment may involve epigenetic factors, such as DNA methylation and histone modifications, to promote type 2 diabetes. The overall objective of our research is to identify the key epigenetic mechanisms influencing the pathogenesis of T2D. We are currently analysing DNA methylation and histone modifications in a number of human cohorts. Here, we examine if non-genetic and genetic factors as well as type 2 diabetes affect epigenetic variation in human tissues. We are further relating DNA methylation to gene expression, in vivo metabolism and type 2 diabetes. Furthermore, we are dissecting the role of epigenetic enzymes in development of type 2 diabetes.
Subject classification (UKÄ)
- Endocrinology and Diabetes
- Cardiology and Cardiovascular Disease
- Medical Genetics and Genomics (including Gene Therapy)
- Cell and Molecular Biology
- Medical Epigenetics and Epigenomics
Free keywords
- Epigenetics
- DNA
- Type 2 diabetes
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Karl Bacos
- Diabetes - Epigenetics - Associate researcher
- EXODIAB: Excellence of Diabetes Research in Sweden - Member of Strategic Research Area
Person: Academic
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Cajsa Davegårdh
- Diabetes - Epigenetics - Doctoral student
- EXODIAB: Excellence of Diabetes Research in Sweden - Member of Strategic Research Area
Person
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Karin Engström
- Division of Occupational and Environmental Medicine, Lund University - Associate professor
- EPI@BIO - Manager
- Diabetes - Epigenetics - Research project participant
Person
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Insulin resistance and type 2 diabetes as allostatic responses to chronic nutrient excess
Prentki, M., Nolan, C. J., James, D. E., Thorens, B., Rhodes, C. J., Corkey, B. E., Ling, C., Froguel, P., Mathieu, C., Gautier, J. F. & Donath, M. Y., 2026 Aug 4, In: Cell Metabolism. 38, 8, p. 1540-1556 17 p.Research output: Contribution to journal › Review article › peer-review
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Predictors of unplanned somatic specialist healthcare during the COVID-19 pandemic among older people with intellectual disabilities: a report from the IDcare study
Axmon, A., Björne, P., Engström, K. & Sandberg, M., 2026 Jul 22.Research output: Contribution to conference › Poster › peer-review
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Access to choice‑enabled healthcare providers among children and adults with intellectual disabilities in comparison with the general population (IDcare)
Axmon, A., Engström, K. & Sandberg, M., 2026 Jun 18, In: BMC Health Services Research. 26, 1Research output: Contribution to journal › Article › peer-review
Open Access
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TBX2 as a Regulator of Pancreatic Islet Function in Type 2 Diabetes
Ofori, J. (Researcher)
2026/08/15 → 2027/06/30
Project: Research
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Novo Nordisk Foundation Nordic Diabetes Prize 2026
Ling, C. (PI)
2026/04/01 → 2027/03/31
Project: Research
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Pharmacoepigenomics for precision medicine in type-2 diabetes
Ling, C. (PI)
Swedish Government Agency for Innovation Systems (Vinnova)
2026/02/01 → 2029/01/31
Project: Research
Activities
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Diabetes Blekinge annual meeting 2025
Vollmer, S. (Role not specified)
2025 Apr 12Activity: Other › Cooperation with society
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Biochimica et Biophysica Acta - General Subjects (Journal)
Bacos, K. (Role not specified)
2024Activity: Publication peer-review and editorial work › Journal/Manuscript peer review
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Diabetes (Journal)
Bacos, K. (Role not specified)
2024Activity: Publication peer-review and editorial work › Journal/Manuscript peer review