• Phone+4640391222, +4640391157
  • Visiting addressShow on map

    CRC, Hus 91 plan 11, Jan Waldenströms gata 35

    Malmö

    Sweden

Unit profile

Description

We are striving towards the identification of disease-modifying mechanisms that protect endogenous insulin release and diabetes development. Ion channels play overarching roles as sensors of cellular activity and control long-term adaptation of the endocrine pancreatic islet to the environmental demands. Our goals concern signals involved in cellular responses to beta-cell overload: 1)Role of voltage-gated Ca2+ channel subunits and Ca2+ signals for beta-cell gene expression, differentiation status, secretory capacity and diabetes 2)Role of non-voltage-gated ion channels and ligands and mechanical signals for beta-cell gene expression, differentiation status, secretory capacity and diabetes. Novel therapeutic approaches: Superparamagnetic nanoparticles as tools for targeted receptor activation and triggering of mechanosensing

UKÄ subject classification

  • Endocrinology and Diabetes
  • Cardiac and Cardiovascular Systems
  • Medical Genetics
  • Cell and Molecular Biology
  • Physiology

Free keywords

  • Type 2 diabetes
  • nano
  • islet

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Collaborations and top research areas from the last five years

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