Division of Molecular Hematology (DMH)

Research output

Research output per year 1990 2016 2017 2018 2020 2021 2022 2022

• 197 Article
• 23 Doctoral Thesis (compilation)
• 14 Review article
• 6 Debate/Note/Editorial
• 16 More
  • 4 Published meeting abstract
  • 3 Book chapter
  • 3 Letter
  • 1 Paper in conference proceeding
  • 1 Entry for encyclopedia/dictionary
  • 1 Abstract
  • 1 Poster
  • 1 Patent
  • 1 Preprint (in preprint archive)

Research output per year

Research output per year

Search results

• 2022

  Alternative splicing modulation by G-quadruplexes

  Georgakopoulos-Soares, I., Parada, G. E., Wong, H. Y., Medhi, R., Furlan, G., Munita, R., Miska, E. A., Kwok, C. K. & Hemberg, M., 2022, In: Nature Communications. 13, 1, 2404.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • UV Melting 100%
  • G-Quadruplexes 99%
  • splicing 86%
  • Potassium Chloride 78%
  • Depolarization 76%

• Antigen-Presenting B Cells Program the Efferent Lymph T Helper Cell Response

  Alsén, S., Cervin, J., Deng, Y., Szeponik, L., Wenzel, U. A., Karlsson, J., Cucak, H., Livingston, M., Bryder, D., Lu, Q., Johansson-Lindbom, B. & Yrlid, U., 2022 Mar, In: Frontiers in Immunology. 13, 813203.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lymph 100%
  • Antigen-Presenting Cells 95%
  • Helper-Inducer T-Lymphocytes 94%
  • B-Lymphocytes 70%
  • Germinal Center 30%

• A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut

  Vergani, S., Muleta, K. G., Da Silva, C., Doyle, A., Kristiansen, T. A., Sodini, S., Krausse, N., Montano, G., Kotarsky, K., Nakawesi, J., Åkerstrand, H., Vanhee, S., Gupta, S. L., Bryder, D., Agace, W. W., Lahl, K. & Yuan, J., 2022, In: Immunity. 55, 10, p. 1829-1842.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Origin of Life 100%
  • Immunoglobulin A 57%
  • B-Lymphocytes 47%
  • Plasma Cells 24%
  • Rotavirus Infections 16%

• A somatic mutation in moesin drives progression into acute myeloid leukemia

  Yuan, O., Ugale, A., de Marchi, T., Anthonydhason, V., Konturek-Ciesla, A., Wan, H., Eldeeb, M., Drabe, C., Jassinskaja, M., Hansson, J., Hidalgo, I., Velasco-Hernandez, T., Cammenga, J., Magee, J. A., Niméus, E. & Bryder, D., 2022, In: Science Advances. 8, 16, eabm9987.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • moesin 100%
  • Acute Myeloid Leukemia 64%
  • Core Binding Factor alpha Subunits 39%
  • Mutation 37%
  • Proteins 24%

• Bmi1 induction protects hematopoietic stem cells against pronounced long-term hematopoietic stress

  Hidalgo, I., Wahlestedt, M., Yuan, O., Zhang, Q., Bryder, D. & Pronk, C. J., 2022, In: Experimental Hematology. 109, p. 35-44

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hematopoietic Stem Cells 100%
  • Hematopoietic Stem Cell Transplantation 30%
  • Maintenance 20%
  • Chimerism 18%
  • Cytostatic Agents 16%

• CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture

  Koide, S., Sigurdsson, V., Radulovic, V., Saito, K., Zheng, Z., Lang, S., Soneji, S., Iwama, A. & Miharada, K., 2022 Jan 21, In: iScience. 25, 1, 103603.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hematopoietic stem cells 100%
  • in vitro culture 68%
  • endoplasmic reticulum stress 61%
  • mast cells 56%
  • mice 41%

• Characterization of Decellularized Implants for Extracellular Matrix Integrity and Immune Response Elicitation

  Banerjee, D., Nayakawde, N. B., Antony, D., Deshmukh, M., Ghosh, S., Sihlbom, C., Berger, E., Ul Haq, U. & Olausson, M., 2022 Jul 1, In: Tissue Engineering - Part A. 28, 13-14, p. 621-639 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Scaffolds 100%
  • Implant 83%
  • Immunosuppressive Agent 74%
  • Extracellular Matrix 71%
  • Immunosuppressive Agents 47%

• Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements

  Bagnara, D., Colombo, M., Reverberi, D., Matis, S., Massara, R., Cardente, N., Ubezio, G., Agostini, V., Agnelli, L., Neri, A., Cardillo, M., Vergani, S., Ghiotto, F., Mazzarello, A. N., Morabito, F., Cutrona, G., Ferrarini, M. & Fais, F., 2022 Jun 23, In: Frontiers in Oncology. 12, 894419.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B-Cell Chronic Lymphocytic Leukemia 100%
  • Immunoglobulins 83%
  • B-Lymphocytes 36%
  • Immunoglobulin Light Chains 27%
  • B-Cell Antigen Receptors 8%

• Ciliated (FOXJ1⁺) Cells Display Reduced Ferritin Light Chain in the Airways of Idiopathic Pulmonary Fibrosis Patients

  Wijk, S. C., Prabhala, P., Löfdahl, A., Nybom, A., Lang, S., Brunnström, H., Bjermer, L., Westergren-Thorsson, G. & Magnusson, M., 2022 Mar, In: Cells. 11, 6, 1031.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apoferritins 100%
  • Ferritin 83%
  • Idiopathic Pulmonary Fibrosis 81%
  • RNA Sequencing 56%
  • Pharmacological Metabolism 26%

• Compositions, constructs and vectors for cell reprogramming (NK cell reprogramming).

  Nascimento Caiado, I. M., Kurochkin, I., Telliam Dushime, G., Sitnicka Quinn, E. & Pereira, F., 2022, Patent No. WO2022129542, 2021 Dec 17, Priority date 2019 Dec 17

  Research output: Patent

• Computational Single-Cell Genomics Methods for Cell State Estimation and their Application to Hematopoietic Systems

  Dhapola, P., 2022, Lund: Lund University, Faculty of Medicine. 91 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  • Stem cells 100%
  • Genomics 73%
  • State estimation 70%
  • Cells 68%
  • RNA 42%

• Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction

  Safi, F., Dhapola, P., Warsi, S., Sommarin, M., Erlandsson, E., Ungerbäck, J., Warfvinge, R., Sitnicka, E., Bryder, D., Böiers, C., Thakur, R. K. & Karlsson, G., 2022 May 10, In: Cell Reports. 39, 6, 110798.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hematopoietic Stem Cells 100%
  • Heterogeneity 93%
  • Tyrosine 92%
  • Chromatin 89%
  • Application 31%

• Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression

  Cai, H., Kondo, M., Sandhow, L., Xiao, P., Johansson, A. S., Sasaki, T., Zawacka-Pankau, J., Tryggvason, K., Ungerstedt, J., Walfridsson, J., Ekblom, M. & Qian, H., 2022 May 19, In: Blood. 139, 20, p. 3040-3057 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hematopoiesis 100%
  • Acute Myeloid Leukemia 87%
  • Reactive Oxygen Metabolite 86%
  • Regeneration 76%
  • Cytarabine 74%

• Developmental cues license megakaryocyte priming in murine hematopoietic stem cells

  Kristiansen, T. A., Zhang, Q., Vergani, S., Boldrin, E., Krausse, N., André, O., Nordenfelt, P., Sigvardsson, M., Bryder, D., Ungerbäck, J. & Yuan, J., 2022, In: Blood Advances. 6, 24 , p. 6228-6241 27 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Megakaryocytes 100%
  • Licensure 89%
  • Hematopoietic Stem Cells 82%
  • Cues 72%
  • Chromatin 14%

• Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner

  Bachiller, S., Hidalgo, I., Garcia, M. G., Boza-Serrano, A., Paulus, A., Denis, Q., Haikal, C., Manouchehrian, O., Klementieva, O., Li, J. Y., Pronk, C. J., Gouras, G. K. & Deierborg, T., 2022 Jun 15, In: Journal of Neuroinflammation. 19, 151.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Psychological Stress 100%
  • Alzheimer Disease 78%
  • Brain 49%
  • Mothers 42%
  • Memory 24%

• Establishment of an immortalized human erythroid cell line sustaining differentiation potential without inducible gene expression system

  Soboleva, S., Kurita, R., Kajitani, N., Åkerstrand, H. & Miharada, K., 2022, In: Human Cell. 35, 1, p. 408-417 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Erythroid Cells 100%
  • Papillomaviridae 48%
  • Gene Expression 47%
  • Cell Line 46%
  • Clone Cells 31%

• Genome-wide association study on 13 167 individuals identifies regulators of blood CD34⁺cell levels

  Lopez de Lapuente Portilla, A., Ekdahl, L., Cafaro, C., Ali, Z., Miharada, N., Thorleifsson, G., Žemaitis, K., Lamarca Arrizabalaga, A., Thodberg, M., Pertesi, M., Dhapola, P., Bao, E., Niroula, A., Bali, D., Norddahl, G., Ugidos Damboriena, N., Sankaran, V. G., Karlsson, G., Thorsteinsdottir, U., Larsson, J., & 2 othersStefansson, K. & Nilsson, B., 2022 Mar 17, In: Blood. 139, 11, p. 1659-1669 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cord 100%
  • Drug Target 92%
  • Threonine 90%
  • Genome-Wide Association Study 84%
  • Hematopoietic Stem Cells 80%

• IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

  Lança, T., Ungerbäck, J., Da Silva, C., Joeris, T., Ahmadi, F., Vandamme, J., Svensson-Frej, M., Mowat, A. M., Kotarsky, K., Sigvardsson, M. & Agace, W. W., 2022 Aug 9, In: Immunity. 55, 8, p. 1431-1447.e11

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • interferon regulatory factor-8 100%
  • Epigenomics 51%
  • Transcription Factors 29%
  • Transcription Factor AP-1 21%
  • Dendritic Cells 17%

• Mesenchymal heterogeneity in the adult human lung

  Kadefors, M., 2022, Lund: Lund University, Faculty of Medicine. 61 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  Open Access

  File

  • Lung 100%
  • Fibroblasts 51%
  • Adventitia 35%
  • Phenotype 29%
  • Extracellular Matrix 24%
  54 Downloads (Pure)

• Molecular Pathogenesis of Leukemia Progression in MLL-ENL Mediated Leukemogenesis

  Yuan, O., 2022, Lund: Lund University, Faculty of Medicine.

  Research output: Thesis › Doctoral Thesis (compilation)

  Open Access

  File
  75 Downloads (Pure)

• Novel Insights into Haematopoietic Stem Cell Regulation and Function

  Warsi, S., 2022, Lund: Lund University, Faculty of Medicine. 82 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  Open Access

  File

  • Hematopoietic Stem Cells 100%
  • Hematopoietic Stem Cell Transplantation 58%
  • Intrinsic Factor 22%
  • Diamond-Blackfan Anemia 14%
  • Hematopoietic System 11%
  73 Downloads (Pure)

• Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a^-/- T Acute Lymphoblastic Leukemia

  Carr, T., McGregor, S., Dias, S., Verykokakis, M., Le Beau, M. M., Xue, H. H., Sigvardsson, M., Bartom, E. T. & Kee, B. L., 2022 Mar, In: Frontiers in Immunology. 13, 845488.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • TCF Transcription Factors 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 72%
  • T-Lymphocytes 45%
  • Mutation 41%
  • Neoplasms 23%

• Overcoming delivery challenges in stem cell biology with nanotechnology

  Schmiderer, L., 2022, Lund: Lund University, Faculty of Medicine. 81 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  • Nanotechnology 100%
  • Hematopoietic Stem Cells 83%
  • Cell Biology 73%
  • Stem Cells 61%
  • Electroporation 23%

• Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome

  Guzzi, N., Muthukumar, S., Cieśla, M., Todisco, G., Ngoc, P. C. T., Madej, M., Munita, R., Fazio, S., Ekström, S., Mortera-Blanco, T., Jansson, M., Nannya, Y., Cazzola, M., Ogawa, S., Malcovati, L., Hellström-Lindberg, E., Dimitriou, M. & Bellodi, C., 2022 Mar, In: Nature Cell Biology. 24, 3, p. 299-306

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pseudouridine 100%
  • Myelodysplastic Syndromes 69%
  • Transfer RNA 67%
  • Hematopoietic Stem Cells 61%
  • Carrier Proteins 39%

• Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence

  Oburoglu, L., Mansell, E., Canals, I., Sigurdsson, V., Guibentif, C., Soneji, S. & Woods, N. B., 2022, In: EMBO Reports. 23, 2

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hemangioblasts 100%
  • Pyruvic Acid 88%
  • Pyruvate 85%
  • Hematopoiesis 67%
  • Pharmacological Metabolism 63%

• Quantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis

  Pimkova, K., Jassinskaja, M., Munita, R., Ciesla, M., Guzzi, N., Cao Thi Ngoc, P., Vajrychova, M., Johansson, E., Bellodi, C. & Hansson, J., 2022 Jul, In: Redox Biology. 53, 102343.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Developmental 100%
  • Hematopoiesis 89%
  • Sulfhydryl Compounds 89%
  • Proteome 86%
  • Hematopoietic Stem Cells 81%

• Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability

  Wray, J. P., Deltcheva, E. M., Boiers, C., Richardson, S., Chhetri, J. B., Brown, J., Gagrica, S., Guo, Y., Illendula, A., Martens, J. H. A., Stunnenberg, H. G., Bushweller, J. H., Nimmo, R. & Enver, T., 2022 Dec, In: Nature Communications. 13, 1, 7124.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA Sequencing 100%
  • Core Binding Factors 94%
  • leukemias 87%
  • vulnerability 83%
  • Cell Death 64%

• Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion

  Verma, G., Bowen, A., Gheibi, S., Hamilton, A., Muthukumar, S., Cataldo, L. R., Asplund, O., Esguerra, J., Karagiannopoulos, A., Lyons, C., Cowan, E., Bellodi, C., Prasad, R., Fex, M. & Mulder, H., 2022, In: The Journal of biological chemistry. 298, 3 , 101692.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mitochondrial Proteins 100%
  • Protein Synthesis 91%
  • Transferases 90%
  • Insulin Derivative 89%
  • Insulin Secretion 87%

• Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data

  Dhapola, P., Rodhe, J., Olofzon, R., Bonald, T., Erlandsson, E., Soneji, S. & Karlsson, G., 2022, In: Nature Communications. 13, 4616.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genomics 100%
  • Sampling 81%
  • Memory 72%
  • Datasets 62%
  • cells 52%

• Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells

  Warsi, S., Dahl, M., Smith, E. M. K., Rydström, A., Mansell, E., Sigurdsson, V., Sjöberg, J., Soneji, S., Rörby, E., Siva, K., Grahn, T. H. M., Liu, Y., Blank, U., Karlsson, G. & Karlsson, S., 2022, In: Haematologica. 107, 12, p. 2884-2896 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hematopoietic Stem Cells 100%
  • Cell Proliferation 18%
  • Transplantation 14%
  • Stem Cells 13%
  • Alleles 13%

• Single-cell transcriptional profiling informs efficient reprogramming of human somatic cells to cross-presenting dendritic cells

  Rosa, F. F., Pires, C. F., Kurochkin, I., Halitzki, E., Zahan, T., Arh, N., Zimmermannová, O., Ferreira, A. G., Li, H., Karlsson, S., Scheding, S. & Pereira, C-F., 2022, In: Science Immunology. 7, 69, p. 1-18 eabg5539.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells 100%
  • Fibroblasts 55%
  • Transcription Factors 41%
  • Antigen Presentation 40%
  • Cross-Priming 26%

• Stem Cells, Hematopoiesis and Lineage Tracing: Transplantation-Centric Views and Beyond

  Konturek-Ciesla, A. & Bryder, D., 2022 Apr 27, In: Frontiers in cell and developmental biology. 10, 903528.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hematopoiesis 100%
  • Cell Lineage 96%
  • Hematopoietic Stem Cells 90%
  • Transplantation 70%
  • Stem Cells 67%

• Survival and risk of vascular complications in myelofibrosis—A population-based study from the Swedish MPN group

  Lindgren, M., Andréasson, B., Samuelsson, J., Pettersson, H., Enblom-Larsson, A., Ravn-Landtblom, A., Scheding, S., Bentham, C. & Ahlstrand, E., 2022 Oct, In: European Journal of Haematology. 109, 4, p. 336-342 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Blood Vessels 100%
  • Survival 94%
  • Population 66%
  • Primary Myelofibrosis 63%
  • Life Expectancy 16%

• Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia

  Sjögren, S. E., Chen, J., Mattebo, A., Alattar, A. G., Karlsson, H., Siva, K., Soneji, S., Tedgård, U., Chen, J. J., Gram, M. & Flygare, J., 2022, In: Experimental Hematology. 105, 0, p. 50-61

  Research output: Contribution to journal › Article › peer-review

  • Diamond-Blackfan Anemia 100%
  • Heme 69%
  • alpha-1-microglobulin 29%
  • Protein Biosynthesis 29%
  • Small Interfering RNA 15%

• The Opportunity of Proteomics to Advance the Understanding of Intra- and Extracellular Regulation of Malignant Hematopoiesis

  Jassinskaja, M. & Hansson, J., 2022 Mar, In: Frontiers in cell and developmental biology. 10, 824098.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hematopoiesis 100%
  • Hematopoietic Stem Cells 90%
  • Proteomics 84%
  • Leukemia 56%
  • Gene Regulatory Networks 24%

• Transcriptomic analysis of functional diversity of human umbilical cord blood hematopoietic stem/progenitor cells in erythroid differentiation

  Soboleva, S., Åkerstrand, H. & Miharada, K., 2022, In: International Journal of Hematology. 115, p. 481-488

  Research output: Contribution to journal › Article › peer-review

  • Hematopoietic Stem Cells 100%
  • Fetal Blood 99%
  • Glycophorins 35%
  • Phosphoric Diester Hydrolases 29%
  • Adenylyl Cyclases 25%

• Tumor purity adjusted beta values improve biological interpretability of high-dimensional DNA methylation data

  Staaf, J. & Aine, M., 2022 Sep, In: PLoS ONE. 17, 9 September, e0265557.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA Methylation 100%
  • Methylation 91%
  • Neoplasms 32%
  • Whole Exome Sequencing 24%
  • Atlases 21%
• 2021

  Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation

  Gerber, J. P., Russ, J., Chandrasekar, V., Offermann, N., Lee, H. M., Spear, S., Guzzi, N., Maida, S., Pattabiraman, S., Zhang, R., Kayvanjoo, A. H., Datta, P., Kasturiarachchi, J., Sposito, T., Izotova, N., Händler, K., Adams, P. D., Marafioti, T., Enver, T., Wenzel, J., & 7 othersBeyer, M., Mass, E., Bellodi, C., Schultze, J. L., Capasso, M., Nimmo, R. & Salomoni, P., 2021, In: Nature Cell Biology. 23, 12, p. 1224-1239 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transcriptional Silencer Elements 100%
  • Chromatin 57%
  • proto-oncogene protein Spi-1 54%
  • Histone Chaperones 50%
  • Myelopoiesis 46%

• Acoustophoresis enables the label-free separation of functionally different subsets of cultured bone marrow stromal cells

  Olm, F., Lim, H. C., Schallmoser, K., Strunk, D., Laurell, T. & Scheding, S., 2021 May 1, In: Cytometry. Part A : the journal of the International Society for Analytical Cytology. 99, 5, p. 476-487 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mesenchymal Stem Cells 100%
  • Cultured Cells 94%
  • Ultrasonic Waves 14%
  • Technology 14%
  • G2 Phase 12%

• Astrovirus VA1/HMO encephalitis after allogeneic hematopoietic cell transplantation: Significant role of immune competence in virus control

  Król, L., Turkiewicz, D., Nordborg, K., Englund, E., Stenberg, L., Karlsson Lindsjö, O., Lind Karlberg, M. & Pronk, C. J., 2021, In: Pediatric Blood and Cancer. 68, 12, e29286.

  Research output: Contribution to journal › Letter › peer-review

• B lymphocyte specification is preceded by extensive epigenetic priming in multipotent progenitors

  Strid, T., Okuyama, K., Tingvall-Gustafsson, J., Kuruvilla, J., Jensen, C. T., Lang, S., Prasad, M., Somasundaram, R., Åhsberg, J., Cristobal, S., Soneji, S., Ungerback, J. & Sigvardsson, M., 2021 Jun, In: Journal of Immunology. 206, 11, p. 2700-2713 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chromatin 100%
  • Epigenomics 98%
  • B-Lymphocytes 87%
  • Transposases 64%
  • Transcription Factors 51%

• CD105⁺CD90⁺CD13⁺ identifies a clonogenic subset of adventitial lung fibroblasts

  Kadefors, M., Rolandsson Enes, S., Åhrman, E., Michaliková, B., Löfdahl, A., Dellgren, G., Scheding, S. & Westergren-Thorsson, G., 2021 Dec 1, In: Scientific Reports. 11, 1, 24417.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adventitia 100%
  • Fibroblasts 61%
  • Lung 44%
  • CD13 Antigens 23%
  • Spatial Analysis 21%

• CellexalVR: A virtual reality platform to visualize and analyze single-cell omics data

  Legetth, O., Rodhe, J., Lang, S., Dhapola, P., Wallergård, M. & Soneji, S., 2021 Nov, In: iScience. 24, 11, 103251.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Single-Cell Analysis 100%
  • Virtual Reality 90%
  • Datasets 14%
  • Software 14%
  • Research Personnel 12%

• Correction of pathology in mice displaying Gaucher disease type 1 by a clinically-applicable lentiviral vector

  Dahl, M., Smith, E. M. K., Warsi, S., Rothe, M., Ferraz, M. J., Aerts, J. M. F. G., Golipour, A., Harper, C., Pfeifer, R., Pizzurro, D., Schambach, A., Mason, C. & Karlsson, S., 2021, In: Molecular Therapy - Methods and Clinical Development. 20, p. 312-323 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gaucher Disease 100%
  • Clinical Trials, Phase I 91%
  • Hematopoietic Stem Cells 74%
  • Pathology 47%

• Defining the Emerging Blood System During Development at Single-Cell Resolution

  Karlsson, G., Sommarin, M. N. E. & Böiers, C., 2021, In: Frontiers in cell and developmental biology. 9, 660350.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hematopoiesis 100%
  • Hematopoietic Stem Cells 45%
  • Single-Cell Analysis 30%
  • Microfluidics 27%
  • Regenerative Medicine 25%

• Developmental changes in the rules for B cell selection*

  Vergani, S. & Yuan, J., 2021, In: Immunological Reviews. 300, 1, p. 194-202

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • B-Lymphocyte Subsets 100%
  • B-Lymphocytes 71%
  • Autoantigens 29%
  • Central Tolerance 20%
  • Psychological Imprinting 19%

• Development of acoustically isolated extracellular plasma vesicles for biomarker discovery in allogeneic hematopoietic stem cell transplantation

  Lim, H. C., Soneji, S., Pálmason, R., Lenhoff, S., Laurell, T. & Scheding, S., 2021, In: Biomarker research. 9, 1, 6.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles 100%
  • Hematopoietic Stem Cell Transplantation 90%
  • Biological Marker 76%
  • MicroRNA 59%
  • Biomarkers 55%

• EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene

  Somasundaram, R., Jensen, C. T., Tingvall-Gustafsson, J., Åhsberg, J., Okuyama, K., Prasad, M., Hagman, J. R., Wang, X., Soneji, S., Strid, T., Ungerbäck, J. & Sigvardsson, M., 2021 Jun 3, In: Blood. 137, 22, p. 3037-3049 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B-Lymphocyte Subsets 100%
  • myc Genes 98%
  • B-Lymphoid Precursor Cells 95%
  • Enhancer 93%
  • Protein 32%

• Editorial: Fetal/Embryonic Hematopoietic Progenitors and Their Impact on Adult Diseases

  Azzoni, E., Böiers, C., Brunelli, S. & Ronchi, A. E., 2021, In: Frontiers in cell and developmental biology. 9, p. 1-3 732649.

  Research output: Contribution to journal › Debate/Note/Editorial

  Open Access

• Genome-wide association study on 13,167 individuals identifies regulators of hematopoietic stem and progenitor cell levels in human blood

  Lopez de Lapuente Portilla, A., Ekdahl, L., Cafaro, C., Ali, Z., Miharada, N., Thorleifsson, G., Zemaitis, K., Lamarca Arrizabalaga, A., Thodberg, M., Pertesi, M., Dhapola, P., Bao, E. L., Niroula, A., Bali, D., Norddahl, G. L., Ugidos Damboriena, N., Sankaran, V. G., Karlsson, G., Thorsteinsdottir, U., Larsson, J., & 2 othersStefánsson, K. & Nilsson, B., 2021 Apr 3, bioRxiv.

  Research output: Working paper/Preprint › Preprint (in preprint archive)

  • Genome-Wide Association Study 100%
  • Hematopoietic Stem Cells 94%
  • Stem Cell Transplantation 10%
  • Blood Cells 8%
  • Stem Cells 7%