Research output per year
Research output per year
- 1 - 50 out of 325 results
Search results
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2025
Unraveling Molecular and Functional Responses Across 3 Lung Injury Models to Expand the Donor Lung Pool
Hirdman, G., Stenlo, M., Bèchet, N. B., Niroomand, A., Mittendorfer, M., Wang, Q., Edström, D., Ghaidan, H., Kjellström, S., Pierre, L., Olm, F., Hyllén, S. & Lindstedt, S., 2025 Feb 19, (E-pub ahead of print) In: Transplantation. 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Functional characterization of tRNA-derived small RNAs in stem cells
Muthukumar, S., Tucciarone, S., Germanos, A. A. & Bellodi, C., 2025, Methods in Enzymology. Academic Press, Vol. 711. p. 261-282 (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Genomic characterization of the HER2-enriched intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer
Hohmann, L., Sigurjonsdottir, K., Campos, A. B., Nacer, D. F., Veerla, S., Rosengren, F., Reddy, P. T., Häkkinen, J., Nordborg, N., Vallon-Christersson, J., Memari, Y., Black, D., Bowden, R., Davies, H. R., Borg, Å., Nik-Zainal, S. & Staaf, J., 2025, In: Nature Communications. 16, p. 1-17 2208.Research output: Contribution to journal › Article › peer-review
Open Access -
PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation
Madej, M., Ngoc, P. C. T., Muthukumar, S., Konturek-Cieśla, A., Tucciarone, S., Germanos, A., Ashworth, C., Kotarsky, K., Ghosh, S., Fan, Z., Fritz, H., Pascual-Gonzalez, I., Huerta, A., Guzzi, N., Colazzo, A., Beneventi, G., Lee, H.-M., Cieśla, M., Douse, C. & Kato, H. & 6 others, , 2025, In: Cell Reports. 44, 6, 115735.Research output: Contribution to journal › Article › peer-review
Open Access -
RNA in Stow, Leukemia on the Go: P-Bodies RNA Sequestration Drives Leukemogenesis
Germanos, A., Muthukumar, S. & Bellodi, C., 2025, (E-pub ahead of print) In: Cellular Reprogramming.Research output: Contribution to journal › Article › peer-review
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2024
A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5
Gamez-Garcia, A., Espinosa-Alcantud, M., Bueno-Costa, A., Alari-Pahissa, E., Marazuela-Duque, A., Thackray, J. K., Ray, C., Berenguer, C., Kumari, P., Bech, J. J., Braun, T., Ianni, A., Tischfield, J. A., Serrano, L., Esteller, M., Sardina, J. L., De La Torre, C., Sigvardsson, M., Vazquez, B. N. & Vaquero, A., 2024 Dec, In: Nature Immunology. 25, 12, p. 2308-2319 12 p.Research output: Contribution to journal › Article › peer-review
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Clinical characteristics in adolescents and young adults with polycythemia vera and essential thrombocythemia in Japan
Sugimoto, Y., Nagaharu, K., Ohya, E., Ohishi, K., Tawara, I., Ito, T., Gotoh, A., Nakamae, M., Kimura, F., Koike, M., Kirito, K., Wada, H., Usuki, K., Tanaka, T., Mori, T., Wakita, S., Saito, T. I., Saito, A. M., Shimoda, K. & Kurokawa, T. & 8 others, , 2024 Dec, In: International Journal of Hematology. 120, 6, p. 684-693 10 p.Research output: Contribution to journal › Article › peer-review
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Lipoprotein metabolism mediates hematopoietic stem cell responses under acute anemic conditions
Saito, K., van der Garde, M., Umemoto, T., Miharada, N., Sjöberg, J., Sigurdsson, V., Shirozu, H., Kamei, S., Radulovic, V., Suzuki, M., Nakano, S., Lang, S., Hansson, J., Olsson, M. L., Minami, T., Gouras, G., Flygare, J. & Miharada, K., 2024 Dec, In: Nature Communications. 15, 1, 8131.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular patterns of resistance to immune checkpoint blockade in melanoma
Lauss, M., Phung, B., Borch, T. H., Harbst, K., Kaminska, K., Ebbesson, A., Hedenfalk, I., Yuan, J., Nielsen, K., Ingvar, C., Carneiro, A., Isaksson, K., Pietras, K., Svane, I. M., Donia, M. & Jönsson, G., 2024 Dec, In: Nature Communications. 15, 1, 3075.Research output: Contribution to journal › Article › peer-review
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Tumor purity estimated from bulk DNA methylation can be used for adjusting beta values of individual samples to better reflect tumor biology
Sasiain, I., Nacer, D. F., Aine, M., Veerla, S. & Staaf, J., 2024 Dec, In: NAR Genomics and Bioinformatics. 6, 4, lqae146.Research output: Contribution to journal › Article › peer-review
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Defective ribosome assembly impairs leukemia progression in a murine model of acute myeloid leukemia
Sjövall, D., Ghosh, S., Fernandez-Fuentes, N., Velasco-Hernandez, T., Hogmalm, A., Menendez, P., Hansson, J., Guibentif, C. & Jaako, P., 2024 Nov 26, In: Cell Reports. 43, 11, 114864.Research output: Contribution to journal › Article › peer-review
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Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response
Warfvinge, R., Geironson Ulfsson, L., Dhapola, P., Safi, F., Sommarin, M., Soneji, S., Hjorth-Hansen, H., Mustjoki, S., Richter, J., Thakur, R. K. & Karlsson, G., 2024 Nov 6, In: eLife. 12Research output: Contribution to journal › Article › peer-review
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Lineage tracing of stem cell-derived dopamine grafts in a Parkinson's model reveals shared origin of all graft-derived cells
Storm, P., Zhang, Y., Nilsson, F., Fiorenzano, A., Krausse, N., Åkerblom, M., Davidsson, M., Yuan, J., Kirkeby, A., Björklund, T. & Parmar, M., 2024 Oct 18, In: Science Advances. 10, 42, p. 1-14 eadn3057.Research output: Contribution to journal › Article › peer-review
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Human monocyte subtype expression of neuroinflammation- and regeneration-related genes is linked to age and sex
Tampé, J. F., Monni, E., Palma-Tortosa, S., Brogårdh, E., Böiers, C., Lindgren, A. G. & Kokaia, Z., 2024 Oct, In: PLoS ONE. 19, 10 October, e0300946.Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, H., Henningsson, R., Puente-Moncada, N., Peña-Martínez, P., Sjöström, L., Ågerstam, H., Sandén, C., Rissler, M., Castor, A., Marquart, H., Modvig, S., Paulsson, K., Pronk, C. J., Schmiegelow, K., Hyrenius-Wittsten, A., Orsmark-Pietras, C., Lilljebjörn, H. & Fioretos, T., 2024 Sept 26, In: Blood. 144, 13, p. 1399-1411Research output: Contribution to journal › Article › peer-review
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Immune system adaptation during gender-affirming testosterone treatment
Lakshmikanth, T., Consiglio, C., Sardh, F., Forlin, R., Wang, J., Tan, Z., Barcenilla, H., Rodriguez, L., Sugrue, J., Noori, P., Ivanchenko, M., Piñero Páez, L., Gonzalez, L., Habimana Mugabo, C., Johnsson, A., Ryberg, H., Hallgren, Å., Pou, C., Chen, Y. & Mikeš, J. & 11 others, , 2024 Sept, In: Nature. 633, 8028, p. 155-164 10 p.Research output: Contribution to journal › Article › peer-review
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(G)Patching up mis-splicing in cancer
Cieśla, M. & Bellodi, C., 2024 Jul, In: Trends in Biochemical Sciences. 49, 7, p. 564-566 3 p.Research output: Contribution to journal › Article › peer-review
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Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration
Engelhard, S., Estruch, M., Qin, S., Engelhard, C. A., Rodriguez-Gonzalez, F. G., Drilsvik, M., Martin-Gonzalez, J., Lu, J. W., Bryder, D., Nerlov, C., Weischenfeldt, J., Reckzeh, K. & Theilgaard-Mönch, K., 2024 Jul, In: Cell Reports. 43, 7, 114475.Research output: Contribution to journal › Article › peer-review
Open Access -
Isolation of Human Bone Marrow Non-hematopoietic Cells for Single-cell RNA Sequencing
Li, H., Bräunig, S. & Scheding, S., 2024 Jun 20, In: Bio-protocol. 14, 12, p. 1-10 e5020.Research output: Contribution to journal › Article › peer-review
Open Access -
A temporal developmental map separates human NK cells from noncytotoxic ILCs through clonal and single-cell analysis
Vo, D. N., Yuan, O., Kanaya, M., Telliam-Dushime, G., Li, H., Kotova, O., Caglar, E., Honnens de Lichtenberg, K., Rahman, S. H., Soneji, S., Scheding, S., Bryder, D., Malmberg, K.-J. & Sitnicka, E., 2024 Jun 11, In: Blood Advances. 8, 11, p. 2933-2951 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Epigenetic dissection of human blood group genes reveals regulatory elements and detailed characteristics of KEL and four other loci
Wu, P. C., McGowan, E. C., Lee, Y. Q., Ghosh, S., Hansson, J. & Olsson, M. L., 2024 Jun, In: Transfusion. 64, 6, p. 1083-1096 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Revitalizing the Aging Immune System Through Selective Stem Cell Targeting
Konturek-Ciesla, A. & Bryder, D., 2024 Jun, In: Cellular Reprogramming. 26, 3, p. 93-95 3 p.Research output: Contribution to journal › Article › peer-review
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Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors—a nationwide, prospective Swedish study
Tesi, B., Robinson, K. L., Abel, F., Díaz de Ståhl, T., Orrsjö, S., Poluha, A., Hellberg, M., Wessman, S., Samuelsson, S., Frisk, T., Vogt, H., Henning, K., Sabel, M., Ek, T., Pal, N., Nyman, P., Giraud, G., Wille, J., Pronk, C. J. & Norén-Nyström, U. & 29 others, , 2024 Apr, In: The Lancet Regional Health - Europe. 39, 100881.Research output: Contribution to journal › Article › peer-review
Open Access -
Ex vivo expansion potential of murine hematopoietic stem cells is a rare property only partially predicted by phenotype
Zhang, Q., Olofzon, R., Konturek-Ciesla, A., Yuan, O. & Bryder, D., 2024 Mar 6, In: eLife. 12, RP91826.Research output: Contribution to journal › Article › peer-review
Open Access -
A complex interplay of intra- and extracellular factors regulates the outcome of fetal- and adult-derived MLL-rearranged leukemia
Jassinskaja, M., Ghosh, S., Watral, J., Davoudi, M., Claesson Stern, M., Daher, U., Eldeeb, M., Zhang, Q., Bryder, D. & Hansson, J., 2024, In: Leukemia. 38, 5, p. 1115-1130Research output: Contribution to journal › Article › peer-review
Open Access -
Early B-Cell Factor 1: An Archetype for a Lineage-Restricted Transcription Factor Linking Development to Disease
Sigvardsson, M., 2024, Transcription factors in blood cell development. Springer Gabler, Vol. 1459. p. 143-156 14 p. (Advances in Experimental Medicine and Biology; vol. 1459).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Hematopoietic stem cell dynamics during regenerative stress
Rydström, A., 2024, Lund: Lund University, Faculty of Medicine. 70 p.Research output: Thesis › Doctoral Thesis (compilation)
Open AccessFile225 Downloads (Pure) -
Implications of stress-induced gene expression for hematopoietic stem cell aging studies
Konturek-Ciesla, A., Olofzon, R., Kharazi, S. & Bryder, D., 2024, In: Nature Aging. 4, 2, p. 177–184 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression
Li, Y., Mendoza-Castrejon, J., Patel, R. M., Casey, E. B., Denby, E., Bryder, D. & Magee, J. A., 2024, In: Leukemia. 38, 3, p. 648-651 4 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Monitoring the Intracellular Fate of Molecular Beacons: The Challenge of False Positive Signals
Volpati, D., Aoki, P. H. B., Johansson, T. B., Munita, R., Ekstrand, F., Ruhrmann, S., Bacos, K., Ling, C. & Prinz, C. N., 2024, In: Advanced NanoBiomed Research. 4, 5Research output: Contribution to journal › Article › peer-review
Open Access -
Ontogeny shapes the ability of ETV6::RUNX1 to enhance hematopoietic stem cell self-renewal and disrupt early lymphopoiesis
Eldeeb, M., Konturek-Ciesla, A., Zhang, Q., Kharazi, S., Tingvall-Gustafsson, J., Ungerbäck, J., Sigvardsson, M. & Bryder, D., 2024, In: Leukemia. 38, 2, p. 455-459 5 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Roles and regulation of tRNA-derived small RNAs in animals
Muthukumar, S., Li, C. T., Liu, R. J. & Bellodi, C., 2024, In: Nature Reviews Molecular Cell Biology. 25, 5, p. 359–378 20 p.Research output: Contribution to journal › Review article › peer-review
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Single-cell analysis of immune recognition in chronic myeloid leukemia patients following tyrosine kinase inhibitor discontinuation
Huuhtanen, J., Adnan-Awad, S., Theodoropoulos, J., Forstén, S., Warfvinge, R., Dufva, O., Bouhlal, J., Dhapola, P., Duàn, H., Laajala, E., Kasanen, T., Klievink, J., Ilander, M., Jaatinen, T., Olsson-Strömberg, U., Hjorth-Hansen, H., Burchert, A., Karlsson, G., Kreutzman, A. & Lähdesmäki, H. & 1 others, , 2024, In: Leukemia. 38, 1, p. 109–125 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response
Fritze, J., Lang, S., Sommarin, M., Soneji, S. & Ahlenius, H., 2024, In: Frontiers in Neuroscience. 18, 1400963.Research output: Contribution to journal › Article › peer-review
Open Access -
Sub-Nanomolar Detection of Oligonucleotides Using Molecular Beacons Immobilized on Lightguiding Nanowires
Johansson, T. B., Davtyan, R., Valderas-Gutiérrez, J., Gonzalez Rodriguez, A., Agnarsson, B., Munita, R., Fioretos, T., Lilljebjörn, H., Linke, H., Höök, F. & Prinz, C. N., 2024, In: Nanomaterials. 14, 5, 453.Research output: Contribution to journal › Article › peer-review
Open Access -
Tracking early mammalian organogenesis - prediction and validation of differentiation trajectories at whole organism scale
Imaz-Rosshandler, I., Rode, C., Guibentif, C., Harland, L. T. G., Ton, M. L. N., Dhapola, P., Keitley, D., Argelaguet, R., Calero-Nieto, F. J., Nichols, J., Marioni, J. C., de Bruijn, M. F. T. R. & Göttgens, B., 2024, In: Development (Cambridge). 151, 3, p. 1-17 17 p.Research output: Contribution to journal › Article › peer-review
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2023
TGF-β Promotes the Postselection Thymic Development and Peripheral Function of IFN-γ-Producing Invariant NKT cells
Morgan, R. C., Frank, C., Greger, M., Attaway, M., Sigvardsson, M., Bartom, E. T. & Kee, B. L., 2023 Nov 1, In: Journal of Immunology. 211, 9, p. 1376-1384 9 p.Research output: Contribution to journal › Article › peer-review
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B-lineage acute lymphoblastic leukemia causes cell-autonomous defects in long-term hematopoietic stem cell function
Jensen, C. T., Åhsberg, J., Tingvall-Gustafsson, J., Somasundaram, R., Lang, S., Ungerbäck, J., Porwit, A., Soneji, S. & Sigvardsson, M., 2023 Nov, In: Haematologica. 108, 11, p. 3175-3180 6 p.Research output: Contribution to journal › Article › peer-review
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Engineered human Diamond-Blackfan anemia disease model confirms therapeutic effects of clinically applicable lentiviral vector at single-cell resolution
Liu, Y., Schmiderer, L., Hjort, M., Lang, S., Bremborg, T., Rydström, A., Schambach, A., Larsson, J. & Karlsson, S., 2023 Nov, In: Haematologica. 108, 11, p. 3095 - 3109 47 p.Research output: Contribution to journal › Article › peer-review
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Functional and molecular profiling of hematopoietic stem cells during regeneration
Rydström, A., Grahn, T. H. M., Niroula, A., Mansell, E., van der Garde, M., Pertesi, M., Subramaniam, A., Soneji, S., Zubarev, R., Enver, T., Nilsson, B., Miharada, K., Larsson, J. & Karlsson, S., 2023 Nov, In: Experimental Hematology. 127, p. 40-51Research output: Contribution to journal › Article › peer-review
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IRF1 regulates self-renewal and stress responsiveness to support hematopoietic stem cell maintenance
Rundberg Nilsson, A. J. S., Xian, H., Shalapour, S., Cammenga, J. & Karin, M., 2023 Oct, In: Science Advances. 9, 43, eadg5391.Research output: Contribution to journal › Article › peer-review
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Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Rodriguez-Zabala, M., Ramakrishnan, R., Reinbach, K., Ghosh, S., Oburoglu, L., Falqués-Costa, A., Bellamkonda, K., Ehinger, M., Peña-Martínez, P., Puente-Moncada, N., Lilljebjörn, H., Cammenga, J., Pronk, C. J., Lazarevic, V., Fioretos, T., Hagström-Andersson, A. K., Woods, N. B. & Järås, M., 2023 Sept 26, In: Blood Advances. 7, 18, p. 5382-5395Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature
Sommarin, M. N. E., Olofzon, R., Palo, S., Dhapola, P., Soneji, S., Karlsson, G. & Böiers, C., 2023 Sept, In: Blood Advances. 7, 18, p. 5325-5340 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Oligodendrocytes in human induced pluripotent stem cell-derived cortical grafts remyelinate adult rat and human cortical neurons
Martinez-Curiel, R., Jansson, L., Tsupykov, O., Avaliani, N., Aretio-Medina, C., Hidalgo, I., Monni, E., Bengzon, J., Skibo, G., Lindvall, O., Kokaia, Z. & Palma-Tortosa, S., 2023 Aug, In: Stem Cell Reports. 18, 8, p. 1643-1656 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery
Rundberg Nilsson, A., Hidalgo, I., Bryder, D. & Pronk, C. J., 2023 Apr 21, In: iScience. 26, 4, 106341.Research output: Contribution to journal › Article › peer-review
Open Access -
m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
Ciesla, M., Cao Thi Ngoc, P., Muthukumar, S., Todisco, G., Madej, M., Fritz, H., Dimitriou, M., Incarnato, D., Hellström-Lindberg, E. & Bellodi, C., 2023 Mar 20, In: Molecular Cell. 83, 7, p. 1165 - 1179.e11Research output: Contribution to journal › Article › peer-review
Open Access -
In vitro clonal multilineage differentiation of distinct murine hematopoietic progenitor populations
Safi, F., Dhapola, P., Erlandsson, E., Ulfsson, L. G., Calderón, A. S., Böiers, C. & Karlsson, G., 2023 Mar 17, In: STAR Protocols. 4, 1, 101965.Research output: Contribution to journal › Article › peer-review
Open Access -
MAC-1 marks a quiescent and functionally superior HSC subset during regeneration
Rydström, A., Mansell, E., Sigurdsson, V., Sjöberg, J., Soneji, S., Miharada, K. & Larsson, J., 2023 Mar 14, In: Stem Cell Reports. 18, 3, p. 736-748 13 p.Research output: Contribution to journal › Article › peer-review
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A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
Eldeeb, M., Yuan, O., Guzzi, N., Thi Ngoc, P. C., Konturek-Ciesla, A., Kristiansen, T. A., Muthukumar, S., Magee, J., Bellodi, C., Yuan, J. & Bryder, D., 2023 Feb 28, In: Cell Reports. 42, 2, 112099.Research output: Contribution to journal › Article › peer-review
Open Access -
IRF1 regulates self-renewal and stress-responsiveness to support hematopoietic stem cell maintenance
Nilsson, A. R., Xian, H., Shalapour, S., Cammenga, J. & Karin, M., 2023 Jan 1, bioRxiv.Research output: Working paper/Preprint › Preprint (in preprint archive)