Research output per year
Research output per year
Unit profile
Research
The department focuses on research that aims to develop gene therapy for hematopoietic cells using viral vectors. Hematopoiesis, in particular the genetic control of hematopoietic cell proliferation and differentiation is also studied in human cell cultures and transgenic mouse model systems.
Description
Dysfunctional blood cell development can have fatal consequences on human health, with implications for several key areas of modern medicine, including amongst others the broad research areas of oncology and immunology. The Division of Molecular Hematology (DMH) aims to generate new knowledge about the regulation of blood cell development by applying recent advances in stem cell technology, in order to dissect the molecular regulation of hematopoiesis. Our mission is to translate this information into clinical contexts to advance the full potential of regenerative medicine.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Units
-
Cell Reprogramming in Hematopoiesis and Immunity
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
-
Hematopoiesis and Gene Therapy
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
-
Hematopoietic Stem Cell Development
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
Profiles
-
Abigail Altman
- Division of Molecular Medicine and Gene Therapy - Student working on a degree project
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
-
Nejc Arh
- Division of Molecular Medicine and Gene Therapy - Doctoral student
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
-
Ervin Ascic
- Division of Molecular Medicine and Gene Therapy - Doctoral student
- Cell Reprogramming in Hematopoiesis and Immunity - Visiting research fellow
- LUCC: Lund University Cancer Centre - Doctoral student
Person
Research output
-
Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses
Xiao, H., Ulmert, I., Bach, L., Huber, J., Narasimhan, H., Kurochkin, I., Chang, Y., Holst, S., Mörbe, U., Zhang, L., Schlitzer, A., Pereira, C. F., Schraml, B. U., Baumjohann, D. & Lahl, K., 2024 Dec, In: Nature Communications. 15, 1, 3554.Research output: Contribution to journal › Article › peer-review
Open Access -
Lipoprotein metabolism mediates hematopoietic stem cell responses under acute anemic conditions
Saito, K., van der Garde, M., Umemoto, T., Miharada, N., Sjöberg, J., Sigurdsson, V., Shirozu, H., Kamei, S., Radulovic, V., Suzuki, M., Nakano, S., Lang, S., Hansson, J., Olsson, M. L., Minami, T., Gouras, G., Flygare, J. & Miharada, K., 2024 Dec, In: Nature Communications. 15, 1, 8131.Research output: Contribution to journal › Article › peer-review
Open Access -
3D cultivation of non-small-cell lung cancer cell lines using four different methods
Malmros, K., Kirova, N., Kotarsky, H., Carlsén, D., Mansour, M. S. I., Magnusson, M., Prabhala, P. & Brunnström, H., 2024 Oct 23, In: Journal of Cancer Research and Clinical Oncology. 150, p. 1-10 472.Research output: Contribution to journal › Article › peer-review
Open Access
-
Identifying, characterising, and targeting chemotherapy-resistant cells in adult B-cell acute lymphoblastic leukaemia
Enver, T. (PI)
2024/01/01 → 2027/12/31
Project: Research
-
Development of Hyper-targeting Pluripotent Stem Cell Derived Natural Killer Cells for Cancer
Woods, N.-B. (PI)
2024/01/01 → 2027/12/31
Project: Research
-
Deciphering the balance between regeneration and tumorigenesis
Leigh, N. (PI)
2024/01/01 → 2026/12/31
Project: Research
Activities
-
UniStem Day 2024: Dissemination and outreach of stem cell science
Ottosson, D. (Organiser), Magnusson, M. (Organiser), Kidnapillai, S. (Organiser), Ahlenius, H. (Organiser), Luis, A. B. (Organiser), Martinez Curiel, R. (Organiser), Laurin, K. (Organiser), Martos Salvo, P. (Organiser), Das, M. (Contributor), Wendler, M. (Contributor), Sivani, B. M. (Contributor), Ramos Passarello, G. (Contributor), Sozzi, E. (Contributor), García Garrote, M. (Contributor), Harrison Umeano, C. (Contributor), Okeke, U. C. (Contributor), Horvath, V. (Contributor), Garza, R. (Contributor), Adami, A. (Contributor), Castilla-Vallmanya, L. (Contributor), Gerdes, P. (Contributor), Pandiloski, N. (Contributor), Jin, Q. (Contributor), de Guidi, C. (Contributor), Palma Tortosa, S. (Contributor), Fritze, J. (Contributor), Jansson, L. I. (Contributor), Robles Rodriguez, L. (Contributor), Pracucci, E. (Contributor), Shen, Y.-P. (Contributor), Trovato, F. (Contributor), Tampé, J. (Contributor), Thakore, R. (Contributor), Stamouli, C.-A. (Contributor), Pinto dos Santos Vaz, C. (Contributor), Aretio, C. (Contributor), Piochon, C. (Contributor), Cepeda-Prado, E. (Contributor), de Jongh, M.-M. (Contributor), Tsalkitzidou, M. (Contributor), Bonsberger, J. (Contributor), Douse, C. (Contributor), Dorazehi, F. (Contributor), Koutounidou, S. (Contributor), Jarl, U. (Contributor), Corsi, S. (Contributor), Bruzelius, A. (Contributor), Mattsson, B. (Contributor), Hammarberg, A. (Contributor), Habekost, M. (Contributor), Prabhala, P. (Contributor), Bremborg, T. (Contributor), Nair, M. S. (Contributor), Burdeyron, P. (Contributor), Mazariegos, M. (Contributor), Björklund, M. (Contributor), Hidalgo, I. (Contributor), Hägg, A. (Invited speaker), Hammarlund, E. (Invited speaker), Mohlin, S. (Invited speaker) & Oesterle, M. (Contributor)
2024 Mar 22Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
-
REPROcode: a single-cell platform to define transcription factors for immune cell reprogramming
Pereira, F. (Role not specified)
2024Activity: Talk or presentation › Invited talk
-
A combinatorial transcription factor screening platform for immune cell reprogramming
Pereira, F. (Invited speaker)
2024Activity: Talk or presentation › Invited talk
Prizes and distinction
-
Docent in Molecular Medicine
Leigh, N. (Recipient), 2023 Oct 2
Prize: Prize (including medals and awards)
-
-
Novo Nordisk Distinguished Innovator Grant
Pereira, F. (Recipient), 2023
Prize: Prize (including medals and awards)