Research output per year
Research output per year
Unit profile
Research
The department focuses on research that aims to develop gene therapy for hematopoietic cells using viral vectors. Hematopoiesis, in particular the genetic control of hematopoietic cell proliferation and differentiation is also studied in human cell cultures and transgenic mouse model systems.
Description
Dysfunctional blood cell development can have fatal consequences on human health, with implications for several key areas of modern medicine, including amongst others the broad research areas of oncology and immunology. The Division of Molecular Hematology (DMH) aims to generate new knowledge about the regulation of blood cell development by applying recent advances in stem cell technology, in order to dissect the molecular regulation of hematopoiesis. Our mission is to translate this information into clinical contexts to advance the full potential of regenerative medicine.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Units
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Cell Reprogramming in Hematopoiesis and Immunity
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
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Hematopoiesis and Gene Therapy
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
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Hematopoietic Stem Cell Development
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
Profiles
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Abigail Altman
- Division of Molecular Medicine and Gene Therapy - Student working on a degree project
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Nejc Arh
- Division of Molecular Medicine and Gene Therapy - Doctoral student
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Ervin Ascic
- Division of Molecular Medicine and Gene Therapy - Doctoral student
- Cell Reprogramming in Hematopoiesis and Immunity - Visiting research fellow
- LUCC: Lund University Cancer Centre - Doctoral student
Person
Research output
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Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses
Xiao, H., Ulmert, I., Bach, L., Huber, J., Narasimhan, H., Kurochkin, I., Chang, Y., Holst, S., Mörbe, U., Zhang, L., Schlitzer, A., Pereira, C. F., Schraml, B. U., Baumjohann, D. & Lahl, K., 2024 Dec, In: Nature Communications. 15, 1, 3554.Research output: Contribution to journal › Article › peer-review
Open Access -
In vivo dendritic cell reprogramming for cancer immunotherapy
Ascic, E., Åkerström, F., Sreekumar Nair, M., Rosa, A., Kurochkin, I., Zimmermannova, O., Catena, X., Rotankova, N., Veser, C., Rudnik, M., Ballocci, T., Schärer, T., Huang, X., de Rosa Torres, M., Renaud, E., Velasco Santiago, M., Met, Ö., Askmyr, D., Lindstedt, M., Greiff, L., & 6 others, 2024 Sept 5, (E-pub ahead of print) In: Science (New York, N.Y.).Research output: Contribution to journal › Article › peer-review
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How to manage patients with germline DDX41 variants: Recommendations from the Nordic working group on germline predisposition for myeloid neoplasms
Baliakas, P., Tesi, B., Cammenga, J., Stray-Pedersen, A., Jahnukainen, K., Andersen, M. K., Ågerstam, H., Creignou, M., Dybedal, I., Raaschou-Jensen, K., Grønbæk, K., Kilpivaara, O., Lindberg, E. H. & Wartiovaara-Kautto, U., 2024 Aug, In: HemaSphere. 8, 8, e145.Research output: Contribution to journal › Article › peer-review
Open Access
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Harnessing the ubiquitin-proteasome system for cancer therapy
Mrs. Berta Kamprad's Cancer Foundation
2024/01/01 → 2027/02/28
Project: Research
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Identifying, characterising, and targeting chemotherapy-resistant cells in adult B-cell acute lymphoblastic leukaemia
2024/01/01 → 2027/12/31
Project: Research
Activities
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UniStem Day 2024: Dissemination and outreach of stem cell science
Daniella Ottosson (Organiser), Mattias Magnusson (Organiser), Srisaiyini Kidnapillai (Organiser), Henrik Ahlenius (Organiser), Alexis Bento Luis (Organiser), Raquel Martinez Curiel (Organiser), Kerstin Laurin (Organiser), Paula Martos Salvo (Organiser), Moubani Das (Contributor), Markus Wendler (Contributor), Bala Mohan Sivani (Contributor), Germán Ramos Passarello (Contributor), Edoardo Sozzi (Contributor), María García Garrote (Contributor), Chimezie Harrison Umeano (Contributor), Ugonna Chidiebere Okeke (Contributor), Vivien Horvath (Contributor), Raquel Garza (Contributor), Anita Adami (Contributor), Laura Castilla-Vallmanya (Contributor), Patricia Gerdes (Contributor), Ninoslav Pandiloski (Contributor), Qianren Jin (Contributor), Claudia de Guidi (Contributor), Sara Palma Tortosa (Contributor), Jonas Fritze (Contributor), Linda I Jansson (Contributor), Laura Robles Rodriguez (Contributor), Enrico Pracucci (Contributor), Yu-Ping Shen (Contributor), Francesco Trovato (Contributor), Juliane Tampé (Contributor), Radhika Thakore (Contributor), Christina-Anastasia Stamouli (Contributor), Cristiana Pinto dos Santos Vaz (Contributor), Constanza Aretio (Contributor), Claire Piochon (Contributor), Efrain Cepeda-Prado (Contributor), Max-Michael de Jongh (Contributor), Maria Tsalkitzidou (Contributor), Jana Bonsberger (Contributor), Christopher Douse (Contributor), Fereshteh Dorazehi (Contributor), Symela Koutounidou (Contributor), Ulla Jarl (Contributor), Sara Corsi (Contributor), Andreas Bruzelius (Contributor), Bengt Mattsson (Contributor), Anna Hammarberg (Contributor), Mette Habekost (Contributor), Pavan Prabhala (Contributor), Tyra Bremborg (Contributor), Malavika Sreekumar Nair (Contributor), Perrine Burdeyron (Contributor), Marina Mazariegos (Contributor), Maria Björklund (Contributor), Isabel Hidalgo (Contributor), Alice Hägg (Invited speaker), Emma Hammarlund (Invited speaker), Sofie Mohlin (Invited speaker) & Marlene Oesterle (Contributor)
2024 Mar 22Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Harnessing Direct Cellular Reprogramming for Cancer Immunotherapy
Filipe Pereira (Invited speaker)
2023 Jun 1Activity: Talk or presentation › Invited talk
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6th Swedish Cancer Research Meeting
Göran B Jönsson (Keynote/plenary speaker), Thoas Fioretos (Keynote/plenary speaker), Sophia Zackrisson (Chair), Yvonne Ceder (Chair), Evangelia Sereti (Session chair), Kajsa Paulsson (Speaker), Anna Sandström Gerdtsson (Speaker), Alexander Pietras (Speaker), Sophie Lehn (Session chair), Ervin Ascic (Speaker), Johann de Bono (Keynote/plenary speaker), Daniel Öhlund (Keynote/plenary speaker), luiz diaz (Keynote/plenary speaker), Anna Martner (Keynote/plenary speaker), Gunilla Enblad (Keynote/plenary speaker), Laura J. Esserman (Keynote/plenary speaker), Olli Kallioniemi (Keynote/plenary speaker) & Regina Beets-Tan (Keynote/plenary speaker)
2023 May 16 → 2023 May 17Activity: Participating in or organising an event › Organisation of conference
File
Prizes and distinction
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Docent in Molecular Medicine
Leigh, Nicholas (Recipient), 2023 Oct 2
Prize: Prize (including medals and awards)
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ERC Proof of Concept Grant
Pereira, Filipe (Recipient), 2023
Prize: Prize (including medals and awards)
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Novo Nordisk Distinguished Innovator Grant
Pereira, Filipe (Recipient), 2023
Prize: Prize (including medals and awards)