Research output per year
Research output per year
Unit profile
Research
The department focuses on research that aims to develop gene therapy for hematopoietic cells using viral vectors. Hematopoiesis, in particular the genetic control of hematopoietic cell proliferation and differentiation is also studied in human cell cultures and transgenic mouse model systems.
Description
Dysfunctional blood cell development can have fatal consequences on human health, with implications for several key areas of modern medicine, including amongst others the broad research areas of oncology and immunology. The Division of Molecular Hematology (DMH) aims to generate new knowledge about the regulation of blood cell development by applying recent advances in stem cell technology, in order to dissect the molecular regulation of hematopoiesis. Our mission is to translate this information into clinical contexts to advance the full potential of regenerative medicine.
Subject classification (UKÄ)
- Medical Genetics and Genomics (including Gene Therapy)
- Hematology
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Units
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Cell Reprogramming in Hematopoiesis and Immunity
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
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Hematopoiesis and Gene Therapy
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
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Hematopoietic Stem Cell Development
Division of Molecular Medicine and Gene Therapy
Organisational unit: Research group
Profiles
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Fritiof Åkerström
- Division of Molecular Medicine and Gene Therapy - Student working on a degree project
- Cell Reprogramming in Hematopoiesis and Immunity - Student working on a degree project
- Melanoma - Doctoral student
Person
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Abigail Altman
- Division of Molecular Medicine and Gene Therapy - Student working on a degree project
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
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Nejc Arh
- Division of Molecular Medicine and Gene Therapy - Doctoral student
- Cell Reprogramming in Hematopoiesis and Immunity - Doctoral student
- LUCC: Lund University Cancer Centre - Doctoral student
Person
Research output
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Ontogeny-specific induction of the KMT2A::AFF1-fusion drives development of a distinct CD24 positive pre-leukemic state
Calderón, A. S., Ghazanfari, R., Masoumi, Z., Kharazi, S., Palo, S., Lang, S., Žemaitis, K., Eldeeb, M., Subramaniam, A., Soneji, S., Stam, R. W., Bryder, D. & Böiers, C., 2025 Sept, In: Leukemia. 39, 9, p. 2099-2111Research output: Contribution to journal › Article › peer-review
Open Access -
Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells
Ascic, E., Fontanari, G., Thrasyvoulou, M., Pérez Bucio, C., Ballocci, T. & Pereira, F., 2025 Aug 1, In: Journal of visualized experiments : JoVE. 222, e68739.Research output: Contribution to journal › Article › peer-review
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Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study
Tesi, B., Robelius, A., Baskin, B., Lazarevic, V., Deneberg, S., Höglund, M., Fogelstrand, L., Ungerstedt, J., Pandzic, T., Tobiasson, M., Garelius, H. G., Kuchinskaya, E., Persson, F., Ågerstam, H., Hallböök, H., Fioretos, T., Nordin, J., Norberg, A., Thuresson, A. C. & Lehmann, S. & 9 others, , 2025 Jul 15, In: Clinical Cancer Research. 31, 14, p. 3062-3071 10 p.Research output: Contribution to journal › Article › peer-review
Open Access
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Advancing Cell-Gene Therapy for Lung Disease: GMP-compliant Engineering and Expansion of Lung Basal Cells for Lung Regeneration
Stevrell, J. (Researcher)
2025/03/24 → …
Project: Dissertation
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In Vivo Dendritic Cell Reprogramming Immunotherapy: Mechanisms, Biomarkers and Combinatorial Therapy
Fontanari, G. (Researcher) & Pereira, F. (Researcher)
2025/02/03 → …
Project: Dissertation
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Uncovering the targeted protein degradation mechanisms in hematopoietic stem cells and cancer
Sivaprasad, R. (Researcher), Subramaniam, A. (Supervisor) & Larsson, J. (Assistant supervisor)
2025/01/01 → …
Project: Dissertation
Activities
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Empowering Immunotherapy with Cellular Reprogramming
Pereira, F. (Role not specified)
2025 Jun 30Activity: Talk or presentation › Invited talk
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In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy.
Pereira, F. (Invited speaker)
2025 Jun 16 → 2025 Jun 18Activity: Talk or presentation › Invited talk
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Empowering Immunotherapy with Cellular Reprogramming
Pereira, F. (Role not specified)
2025 Jun 11Activity: Talk or presentation › Invited talk
Prizes and distinction
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Imperial College Emerging Alumni Leader Aw
Pereira, F. (Recipient), 2025
Prize: Prize (including medals and awards)
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Pfizer-Portugal award in basic research
Pereira, F. (Recipient), 2024
Prize: Prize (including medals and awards)