Experimental Cancer Research, Malmö

Research output

Research output per year 2008 2013 2014 2015 2016 2017 2022

• 50 Article
• 4 Review article
• 4 Doctoral Thesis (compilation)
• 2 Letter
• 1 More
  • 1 Debate/Note/Editorial

Research output per year

Research output per year

Search results

• 2022

  FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer

  Larsson, P. F., Karlsson, R., Sarwar, M., Miftakhova, R., Wang, T., Syed Khaja, A. S., Semenas, J., Chen, S., Hedblom, A., Ali, A., Ekström-Holka, K., Simoulis, A., Kumar, A., Wingren, A. G., Robinson, B., Nyunt Wai, S., Mongan, N. P., Heery, D. M., Öhlund, D., Grundström, T., & 2 othersØdum, N. & Persson, J. L., 2022, In: Molecular Oncology. 16, 13 , p. 2496-2517

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fc Receptors 100%
  • Androgen Receptors 89%
  • Prostatic Neoplasms 66%
  • Neoplasm Metastasis 51%
  • Growth 42%

• Sialyl-Tn Antigen-Imprinted Dual Fluorescent Core-Shell Nanoparticles for Ratiometric Sialyl-Tn Antigen Detection and Dual-Color Labeling of Cancer Cells

  Jiang, S., Wang, T., Behren, S., Westerlind, U., Gawlitza, K., Persson, J. L. & Rurack, K., 2022 Dec 23, In: ACS Applied Nano Materials. 5, 12, p. 17592-17605 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Core shell nanoparticles 100%
  • Antigens 73%
  • Molecularly Imprinted Polymer 58%
  • Labeling 53%
  • Cells 53%
• 2021

  Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration-resistant prostate cancer

  Semenas, J., Wang, T., Sajid Syed Khaja, A., Firoj Mahmud, A. K. M., Simoulis, A., Grundström, T., Fällman, M. & Persson, J. L., 2021, In: Molecular Oncology. 15, 4, p. 968-986 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ISA-2011B 100%
  • Castration 82%
  • Tamoxifen 79%
  • Psychological Inhibition 61%
  • Prostatic Neoplasms 59%
• 2020

  Development and validation of a 25-Gene Panel urine test for prostate cancer diagnosis and potential treatment follow-up

  Johnson, H., Guo, J., Zhang, X., Zhang, H., Simoulis, A., Wu, A. H. B., Xia, T., Li, F., Tan, W., Johnson, A., Dizeyi, N., Abrahamsson, P. A., Kenner, L., Feng, X., Zou, C., Xiao, K., Persson, J. L. & Chen, L., 2020, In: BMC Medicine. 18, 1, 376.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Prostatic Neoplasms 100%
  • Urine 89%
  • Area Under Curve 64%
  • Genes 50%
  • Biopsy 47%

• Establishing a Urine-Based Biomarker Assay for Prostate Cancer Risk Stratification

  Guo, J., Liu, D., Zhang, X., Johnson, H., Feng, X., Zhang, H., Wu, A. H. B., Chen, L., Fang, J., Xiao, Z., Xiao, K., Persson, J. L. & Zou, C., 2020, In: Frontiers in cell and developmental biology. 8, 597961.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Area Under Curve 100%
  • Prostatic Neoplasms 97%
  • Urine 87%
  • Biomarkers 79%
  • Neoplasm Grading 68%

• Establishment of prostate tumor growth and metastasis is supported by bone marrow cells and is mediated by pip5k1α lipid kinase

  Karlsson, R., Larsson, P., Miftakhova, R., Khaja, A. S. S., Sarwar, M., Semenas, J., Chen, S., Hedblom, A., Wang, T., Ekström-Holka, K., Simoulis, A., Kumar, A., Ødum, N., Grundström, T. & Persson, J. L., 2020, In: Cancers. 12, 9, 19 p., 2719.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bone Marrow Cells 100%
  • Prostate 88%
  • Phosphotransferases 81%
  • Lipids 69%
  • Neoplasm Metastasis 65%

• Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells

  Gomzikova, M. O., Aimaletdinov, A. M., Bondar, O. V., Starostina, I. G., Gorshkova, N. V., Neustroeva, O. A., Kletukhina, S. K., Kurbangaleeva, S. V., Vorobev, V. V., Garanina, E. E., Persson, J. L., Jeyapalan, J., Mongan, N. P., Khaiboullina, S. F. & Rizvanov, A. A., 2020, In: Scientific Reports. 10, 1, 10740.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytochalasin B 100%
  • Extracellular Vesicles 91%
  • Mesenchymal Stem Cells 69%
  • Immunosuppressive Agents 64%
  • Membranes 46%

• The functional interlink between AR and MMP9/VEGF signaling axis is mediated through PIP5K1α/pAKT in prostate cancer

  Larsson, P., Syed Khaja, A. S., Semenas, J., Wang, T., Sarwar, M., Dizeyi, N., Simoulis, A., Hedblom, A., Wai, S. N., Ødum, N. & Persson, J. L., 2020 Mar 15, In: International Journal of Cancer. 146, 6, p. 1686-1699 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Androgen Receptors 100%
  • Matrix Metalloproteinase 9 99%
  • Vascular Endothelial Growth Factor A 79%
  • Prostatic Neoplasms 73%
  • Cyclin A1 14%
• 2019

  Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury

  Hedblom, A., Hejazi, S. M., Canesin, G., Choudhury, R., Hanafy, K. A., Csizmadia, E., Persson, J. L. & Wegiel, B., 2019 Feb 1, In: Cell Death and Disease. 10, 2, 72.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heme Oxygenase-1 100%
  • Heme 94%
  • DNA Damage 55%
  • TOR Serine-Threonine Kinases 47%
  • Cellular Senescence 46%

• The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor

  Sarwar, M., Syed Khaja, A. S., Aleskandarany, M., Karlsson, R., Althobiti, M., Ødum, N., Mongan, N. P., Dizeyi, N., Johnson, H., Green, A. R., Ellis, I. O., Rakha, E. A. & Persson, J. L., 2019, In: Oncogene. 38, 3, p. 375-389 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ISA-2011B 100%
  • Breast Neoplasms 53%
  • Triple Negative Breast Neoplasms 50%
  • 1-phosphatidylinositol-4-phosphate 5-kinase 45%
  • Growth 41%
• 2018

  A panel of biomarkers for diagnosis of prostate cancer using urine samples

  Guo, J., Yang, J., Zhang, X., Feng, X., Zhang, H., Chen, L., Johnson, H., Persson, J. L. & Xiao, K., 2018 Mar 1, In: Anticancer research. 38, 3, p. 1471-1477 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms 100%
  • Urine 89%
  • Biomarkers 82%
  • Prostate-Specific Antigen 38%
  • Area Under Curve 20%

• SATB1 in Malignant T Cells

  Fredholm, S., Willerslev-Olsen, A., Met, Ö., Kubat, L., Gluud, M., Mathiasen, S. L., Friese, C., Blümel, E., Petersen, D. L., Hu, T., Nastasi, C., Lindahl, L. M., Buus, T. B., Krejsgaard, T., Wasik, M. A., Kopp, K. L., Koralov, S. B., Persson, J. L., Bonefeld, C. M., Geisler, C., & 4 othersWoetmann, A., Iversen, L., Becker, J. C. & Ødum, N., 2018, In: Journal of Investigative Dermatology. 138, 8, p. 1805-1815

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-9 100%
  • Interleukin-5 77%
  • Cutaneous T-Cell Lymphoma 59%
  • MicroRNAs 58%
  • T-Lymphocytes 42%

• The interplay between AR, EGF receptor and MMP-9 signaling pathways in invasive prostate cancer

  Mandel, A., Larsson, P., Sarwar, M., Semenas, J., Syed Khaja, AS. & Persson, J. L., 2018 Jun 27, In: Molecular Medicine. 24, 34, p. 1-13

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The role of phosphatidylinositol 4-phosphate 5-kinase type І alpha (PIP5K1α) and utility of its inhibitor for targeting metastatic cancer

  Sarwar, M., 2018, Lund: Lund University: Faculty of Medicine. 61 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  Open Access

  File

  • ISA-2011B 100%
  • 1-phosphatidylinositol-4-phosphate 5-kinase 94%
  • Castration 51%
  • Prostatic Neoplasms 45%
  • Androgen Receptors 33%
  399 Downloads (Pure)
• 2017

  Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development

  Metzler, V. M., de Brot, S., Robinson, R. S., Jeyapalan, J. N., Rakha, E., Walton, T., Gardner, D. S., Lund, E. F., Whitchurch, J., Haigh, D., Lochray, J. M., Robinson, B. D., Allegrucci, C., Fray, R. G., Persson, J. L., Ødum, N., Miftakhova, R. R., Rizvanov, A., Hughes, I. A., Tadokoro-Cuccaro, R., & 3 othersHeery, D. M., Rutland, C. S. & Mongan, N. P., 2017, In: Placenta. 56, p. 79-85

  Research output: Contribution to journal › Article › peer-review

  • Placentation 100%
  • Androgens 72%
  • Neoplasms 25%
  • Androgen Receptors 24%
  • Placenta 21%

• Cytochalasin B-induced membrane vesicles convey angiogenic activity of parental cells

  Gomzikova, M. O., Zhuravleva, M. N., Miftakhova, R. R., Arkhipova, S. S., Evtugin, V. G., Khaiboullina, S. F., Kiyasov, A. P., Persson, J. L., Mongan, N. P., Pestell, R. G. & Rizvanov, A., 2017, In: Oncotarget. 8, 41, p. 70496-70507 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytochalasin B 100%
  • Extracellular Vesicles 91%
  • Membranes 46%
  • Vascular Endothelial Growth Factor A 16%
  • Communication 14%

• Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome

  Atiomo, W., Shafiee, M. N., Chapman, C., Metzler, V. M., Abouzeid, J., Latif, A., Chadwick, A., Kitson, S., Sivalingam, V. N., Stratford, I. J., Rutland, C. S., Persson, J. L., Ødum, N., Fuentes-Utrilla, P., Jeyapalan, J. N., Heery, D. M., Crosbie, E. J. & Mongan, N. P., 2017 Nov 1, In: Clinical Endocrinology. 87, 5, p. 557-565 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • NAD(P)H Dehydrogenase (Quinone) 100%
  • Polycystic Ovary Syndrome 76%
  • Endometrium 71%
  • Endometrial Neoplasms 70%
  • Ovarian Neoplasms 37%

• Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor-γ (PPARγ) are disrupted by retinal disease-associated mutations

  Fulton, J., Mazumder, B., Whitchurch, J. B., Monteiro, C. J., Collins, H. M., Chan, C. M., Clemente, M. P., Hernandez-Quiles, M., Stewart, E. A., Amoaku, W. M., Moran, P. M., Mongan, N. P., Persson, J. L., Ali, S. & Heery, D. M., 2017 Mar 16, In: Cell Death and Disease. 8, 3, p. e2677

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retinal Diseases 100%
  • Peroxisome Proliferator-Activated Receptors 97%
  • Cytoplasmic and Nuclear Receptors 83%
  • Mutation 45%
  • Ligands 25%

• HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells

  Shah, M., Cardenas, R., Wang, B., Persson, J., Mongan, N. P., Grabowska, A. & Allegrucci, C., 2017 Feb 16, In: Molecular Cancer. 16, p. 1-19 38.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplastic Stem Cells 100%
  • Homeobox Genes 72%
  • Stem Cells 69%
  • Breast Neoplasms 60%
  • Breast 23%

• ISA-2011B, a phosphatidylinositol 4-phosphate 5-kinase a inhibitor, impairs CD28-dependent costimulatory and pro-inflammatory signals in human T lymphocytes

  Kunkl, M., Porciello, N., Mastrogiovanni, M., Capuano, C., Lucantoni, F., Moretti, C., Persson, J. L., Galandrini, R., Buzzetti, R. & Tuosto, L., 2017 Apr 26, In: Frontiers in Immunology. 8, APR, 502.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ISA-2011B 100%
  • 1-phosphatidylinositol-4-phosphate 5-kinase 68%
  • T-Lymphocytes 25%
  • Cytokines 19%
  • Phosphatidylinositol 4,5-Diphosphate 16%

• T Cell Activation Pathways: B7, LFA-3, and ICAM-1 Shape Unique T Cell Profiles

  Wingren, A. G., Parra, E., Varga, M., Kalland, T., Sjogren, H. O., Hedlund, G. & Dohlsten, M., 2017, In: Critical Reviews in Immunology. 37, 2-6, p. 463-481 19 p.

  Research output: Contribution to journal › Article › peer-review

  • CD58 Antigens 100%
  • Intercellular Adhesion Molecule-1 66%
  • Helper-Inducer T-Lymphocytes 66%
  • Lymphocyte Function-Associated Antigen-1 41%
  • T-Lymphocytes 39%
• 2016

  Cyclin A1 and P450 aromatase promote metastatic homing and growth of stem-like prostate cancer cells in the bone marrow.

  Miftakhova, R., Hedblom, A., Semenas, J., Robinson, B. D., Simoulis, A., Malm, J., Rizvanov, A., Heery, D., Mongan, N. P., Maitland, N. J., Allegrucci, C. & Persson, J. L., 2016, In: Cancer Research. 76, 8, p. 2453-2464

  Research output: Contribution to journal › Article › peer-review

  • Cyclin A1 100%
  • Aromatase 70%
  • Bone Marrow Cells 54%
  • Prostatic Neoplasms 45%
  • Bone Marrow 35%

• Demonstration of a WNT5A-IL-6 positive feedback loop in melanoma cells: Dual interference of this loop more effectively impairs melanoma cell invasion

  Linnskog, R., Mohapatra, P., Moradi, F., Prasad, C. P. & Andersson, T., 2016, In: Oncotarget. 7, 25, p. 37790-37802 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Melanoma 100%
  • Interleukin-6 92%
  • Proteins 17%
  • Cultured Cells 10%
  • Small Interfering RNA 10%

• Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical Applications

  Rizvanov, A., Persson, J., Şahin, F., Bellusci, S. & Oliveira, J. P., 2016, In: Stem Cells International. 2016, 3157365.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• STAT5 induces miR-21 expression in cutaneous T cell lymphoma

  Lindahl, L. M., Fredholm, S., Joseph, C., Nielsen, B. S., Jønson, L., Willerslev-Olsen, A., Gluud, M., Blümel, E., Petersen, D. L., Sibbesen, N., Hu, T., Nastasi, C., Krejsgaard, T., Jæhger, D., Persson, J. L., Mongan, N., Wasik, M. A., Litvinov, I. V., Sasseville, D., Koralov, S. B., & 6 othersBonefeld, C. M., Geisler, C., Woetmann, A., Ralfkiaer, E., Iversen, L. & Odum, N., 2016 Jun 18, In: Oncotarget. 7, 29, p. 45730-45744 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cutaneous T-Cell Lymphoma 100%
  • Sezary Syndrome 55%
  • Cytokines 47%
  • T-Lymphocytes 47%
  • Interleukin-2 45%
  263 Downloads (Pure)

• Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells

  Sarwar, M., Semenas, J., Miftakhova, R., Simoulis, A., Robinson, B., Wingren, A. G., Mongan, N. P., Heery, D. M., Johnsson, H., Abrahamsson, P-A., Dizeyi, N., Luo, J. & Persson, J. L., 2016, In: Oncotarget. 7, 39, p. 63065-63081

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MDV 3100 100%
  • ISA-2011B 65%
  • Prostatic Neoplasms 53%
  • 1-phosphatidylinositol-4-phosphate 5-kinase 44%
  • Heterografts 36%

• The expression of IL-21 is promoted by MEKK4 in malignant T cells and associated with increased progression risk in cutaneous T-cell lymphoma

  Fredholm, S., Livinov, I., Mongan, N. P., Schiele, S., Willerslev-Olsen, A., Petersen, D. L., Krejsgaard, T., Sibbesen, N., Nastasi, C., Bonefeld, C. M., Persson, J. L., Thor Straten, P., Andersen, M. H., Koralov, S. B., Wasik, M., Geisler, C., Sasseville, D., Woetmann, A. & Ødum, N., 2016 Apr, In: Journal of Investigative Dermatology. 136, 4, p. 866-869

  Research output: Contribution to journal › Letter › peer-review

• Use of two gene panels for prostate cancer diagnosis and patient risk stratification.

  Xiao, K., Guo, J., Zhang, X., Feng, X., Zhang, H., Cheng, Z., Johnson, H., Persson, J. L. & Chen, L., 2016, In: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms 100%
  • Genes 50%
  • Biomarkers 25%
  • Sensitivity and Specificity 19%
  • Area Under Curve 16%

• Vitronectin: a promising breast cancer serum biomarker for early diagnosis of breast cancer in patients.

  Hao, W., Zhang, X., Xiu, B., Yang, X., Hu, S., Liu, Z., Duan, C., Jin, S., Ying, X., Zhao, Y., Han, X., Hao, X., Fan, Y., Johnson, H., Meng, D., Persson, J. L., Zhang, H., Feng, X. & Huang, Y., 2016, In: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

  Research output: Contribution to journal › Article › peer-review

  • Vitronectin 100%
  • Tumor Biomarkers 72%
  • Early Detection of Cancer 70%
  • Breast Neoplasms 47%
  • Serum 33%
• 2015

  Cyclin A1 regulates the interactions between mouse hematopoietic stem and progenitor cells and their niches.

  Miftakhova, R., Hedblom, A., Batkiewicz, L., Anagnosaki, L., Zhang, Y., Sjölander, A., Gjörloff Wingren, A., Wolgemuth, D. J. & Persson, J. L., 2015, In: Cell Cycle. 14, 12, p. 1948-1960

  Research output: Contribution to journal › Article › peer-review

  • Cyclin A1 100%
  • Hematopoietic Stem Cells 56%
  • Vascular Endothelial Growth Factor Receptor-1 18%
  • BM-cyclin 10%
  • Microvessels 4%

• Heme oxygenase-1 in macrophages controls prostate cancer progression.

  Nemeth, Z., Li, M., Csizmadia, E., Döme, B., Johansson, M., Persson, J. L., Seth, P., Otterbein, L. & Wegiel, B., 2015, In: Oncotarget. 6, 32, p. 33675-33688

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Heme Oxygenase-1 100%
  • Prostatic Neoplasms 67%
  • Macrophages 59%
  • Cadherins 43%
  • Heterografts 28%

• Induction of morphological changes in death-induced cancer cells monitored by holographic microscopy.

  El-Schish, Z., Mölder, A., Tassidis, H., Härkönen, P., Falck Miniotis, M. & Gjörloff Wingren, A., 2015, In: Journal of Structural Biology. 189, 3, p. 207-212

  Research output: Contribution to journal › Article › peer-review

  • Microscopy 100%
  • Etoposide 77%
  • Cell Death 54%
  • Cell Line 42%
  • Neoplasms 38%

• Interfacing antibody-based microarrays and digital holography enables label-free detection for loss of cell volume

  El-Schich, Z., Nilsson, E., Sandström Gerdtsson, A., Wingren, C. & Gjörloff Wingren, A., 2015 Mar 20, In: Future science OA.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Holography 100%
  • Cell Size 58%
  • Antibodies 31%
  • Microscopy 21%
  • Etoposide 18%

• MIR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.

  Nilsson, E. M., Laursen, K. B., Whitchurch, J., McWilliam, A., Ødum, N., Persson, J. L., Heery, D. M., Gudas, L. J. & Mongan, N. P., 2015, In: Oncotarget. 6, 34, p. 35710-35725 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gene Regulatory Networks 100%
  • Androgens 84%
  • Androgen Receptors 66%
  • Prostatic Neoplasms 40%
  • Mediator Complex Subunit 1 36%
  213 Downloads (Pure)

• Regulation of vascular endothelial growth factor (VEGF) in prostate cancer.

  de Brot, S., Ntekim, A., Cardenas, R., James, V., Allegrucci, C., Heery, D., Bates, D. O., Odum, N., Persson, J. L. & Mongan, N. P., 2015, In: Endocrine-Related Cancer. 22, 3, p. R107-R123

  Research output: Contribution to journal › Review article › peer-review

  • Vascular Endothelial Growth Factor A 100%
  • Prostatic Neoplasms 92%
  • Androgens 42%
  • taxane 14%
  • Neoplasm Metastasis 14%
• 2014

  A transient peak of infections during onset of rheumatoid arthritis: a 10-year prospective cohort study.

  Arleevskaya, M. I., Gabdoulkhakova, A., Filina, Y. V., Miftakhova, R., Bredberg, A. & Tsybulkin, A. P., 2014, In: BMJ Open. 4, 8, p. e005254

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Rheumatoid Arthritis 100%
  • Cohort Studies 82%
  • Prospective Studies 77%
  • Infections 57%
  • Immunity 32%
  47 Downloads (Pure)

• Digital holographic microscopy for non-invasive monitoring of cell cycle arrest in l929 cells.

  Falck Miniotis, M., Mukwaya, A. & Gjörloff Wingren, A., 2014, In: PLoS ONE. 9, 9, e106546.

  Research output: Contribution to journal › Article › peer-review

  File

  • Cell Cycle Checkpoints 100%
  • Microscopy 85%
  • Cell Size 69%
  • Cell Cycle 40%
  • Etoposide 36%
  138 Downloads (Pure)

• Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells.

  Wegiel, B., Hedblom, A., Li, M., Gallo, D., Csizmadia, E., Harris, C., Nemeth, Z., Zuckerbraun, B. S., Soares, M., Persson, J. L. & Otterbein, L. E., 2014, In: Cell Death & Disease. 5, Mar 20, e1139.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Heme Oxygenase-1 100%
  • Myeloid Cells 87%
  • Carbon Monoxide 86%
  • Macrophages 49%
  • Macrophage Colony-Stimulating Factor Receptors 42%
  220 Downloads (Pure)

• Inhibition of WNT5A Signaling and Function in Malignant Melanoma

  Linnskog, R., 2014, Department of Laboratory Medicine, Lund University. 130 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  • Melanoma 100%
  • Interleukin-6 38%
  • Cell Movement 16%
  • Neoplasm Metastasis 12%
  • p38 Mitogen-Activated Protein Kinases 10%
  2 Downloads (Pure)

• Protein kinase A (PKA) pathway is functionally linked to androgen receptor (AR) in the progression of prostate cancer.

  Sarwar, M., Sandberg, S., Abrahamsson, P-A. & Persson, J. L., 2014, In: Urologic Oncology. 32, 1

  Research output: Contribution to journal › Article › peer-review

  • Androgen Receptors 100%
  • Cyclic AMP-Dependent Protein Kinases 96%
  • Prostatic Neoplasms 73%
  • Cyclic AMP 68%
  • Prostate-Specific Antigen 35%

• Response mechanisms of normal hematopoietic cells and leukemic cells to genotoxic agents and novel therapeutic strategies

  Hedblom, A., 2014, Experimental cancer research. 62 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  • Cyclin A1 100%
  • Heme Oxygenase-1 67%
  • ISA-2011B 55%
  • Hematopoietic Stem Cells 45%
  • DNA Damage 39%

• The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.

  Semenas, J., Hedblom, A., Miftakhova, R., Sarwar, M., Larsson, R., Shcherbina, L., Johansson, M., Härkönen, P., Sterner, O. & Persson, J. L., 2014, In: Proceedings of the National Academy of Sciences. 111, 35, p. E3689-E3698

  Research output: Contribution to journal › Article › peer-review

  • ISA-2011B 100%
  • Phosphatidylinositol 3-Kinases 41%
  • Prostatic Neoplasms 32%
  • PC-3 Cells 20%
  • Tetrahydroisoquinolines 15%
• 2013

  CDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemia.

  Hedblom, A., Laursen, K. B., Miftakhova, R., Sarwar, M., Anagnostaki, L., Bredberg, A., Mongan, N., Gudas, L. J. & Persson, J. L., 2013, In: Cell Cycle. 12, 8, p. 1251-1266

  Research output: Contribution to journal › Article › peer-review

  • Tretinoin 100%
  • Acute Myeloid Leukemia 93%
  • Leukemia 22%
  • cdc25 Phosphatases 22%
  • Cell Cycle 21%

• Cyclin A1 modulates the expression of vascular endothelial growth factor and promotes hormone-dependent growth and angiogenesis of breast cancer.

  Syed Khaja, A. S., Dizeyi, N., Kopparapu, P. K., Anagnostaki, L., Härkönen, P. & Persson, J. L., 2013, In: PLoS ONE. 8, 8, e72210.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cyclin A1 100%
  • Vascular Endothelial Growth Factors 54%
  • Growth Hormone 54%
  • Vascular Endothelial Growth Factor A 49%
  • Breast Neoplasms 36%
  231 Downloads (Pure)

• Enzalutamide as a second generation antiandrogen for treatment of advanced prostate cancer

  Semenas, J., Dizeyi, N. & Persson, J. L., 2013, In: Drug Design, Development and Therapy. 7, p. 875-881

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Enzalutamide 100%
  • Antiandrogen 83%
  • MDV 3100 78%
  • Androgen Antagonists 70%
  • Androgen 67%
  191 Downloads (Pure)

• Expression of cyclin d1 and its association with disease characteristics in bladder cancer.

  Kopparapu, P., Boorjian, S. A., Robinson, B. D., Downes, M., Gudas, L. J., Mongan, N. & Persson, J. L., 2013, In: Anticancer research. 33, 12, p. 5235-5242

  Research output: Contribution to journal › Article › peer-review

  • Cyclin D1 100%
  • Urinary Bladder Neoplasms 88%
  • Urinary Bladder 73%
  • Cell Cycle 72%
  • Carcinoma 61%

• Expression of VEGF and Its receptors VEGFR1/VEGFR2 Is Associated with Invasiveness of Bladder Cancer.

  Kopparapu, P. K., Boorjian, S. A., Robinson, B. D., Downes, M., Gudas, L. J., Mongan, N. & Persson, J. L., 2013, In: Anticancer research. 33, 6, p. 2381-2390

  Research output: Contribution to journal › Article › peer-review

  • Vascular Endothelial Growth Factor Receptor 100%
  • Urinary Bladder Neoplasms 79%
  • Vascular Endothelial Growth Factor A 47%
  • Muscle Neoplasms 42%
  • Recurrence 15%

• Interaction between c-jun and Androgen Receptor Determines the Outcome of Taxane Therapy in Castration Resistant Prostate Cancer.

  Tinzl, M., Chen, B., Chen, S-Y., Semenas, J., Abrahamsson, P-A. & Dizeyi, N., 2013, In: PLoS ONE. 8, 11, e79573.

  Research output: Contribution to journal › Article › peer-review

  File

  • taxane 100%
  • Castration 85%
  • Androgen Receptors 83%
  • Prostatic Neoplasms 61%
  • Docetaxel 52%
  157 Downloads (Pure)

• miR-155 meets the JAK/STAT pathway.

  Persson, J. L., 2013, In: Cell Cycle. 12, 14, p. 2170-2170

  Research output: Contribution to journal › Debate/Note/Editorial › peer-review

• miRNA in mycosis fungoides and skin inflammation.

  Persson, J. L., 2013, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 121, 11, p. 1017-1019

  Research output: Contribution to journal › Review article › peer-review

  • Cutaneous T-Cell Lymphoma 100%
  • Mycosis Fungoides 99%
  • MicroRNAs 65%
  • Cytokines 47%
  • T-Lymphocytes 47%