Experimental Epilepsy Group

  • Visiting addressShow on map

    Wallenberg Neuroscience Center, BMC A11, Sölveg 17

    221 84 Lund

    Sweden

  • Postal addressShow on map

    Sölvegatan 17, BMC A11

    221 84 Lund

    Sweden

Unit profile

Research

Epilepsy is one of the most devastating neurological diseases, affecting at least 60 million people worldwide. But despite certain progress in antiepileptic drug developmental, available pharmacological treatments are only symptomatic, have side effects and fail to adequately control seizures in a third of patients. Recently, neuropeptides and neurotrophic factors emerged as strong regulators of synaptic transmission in the CNS, offering a potent tool to counteract the seizure activity. However, it is not clear yet what the role of these agents is in mechanisms of epileptogenesis. We do research to develop gene therapy strategies based on neuropeptides and neurotrophic factors. We also use optogenetics and chemogenetics as tools to investigate mechanisms of epileptogenesis with the aim to develop these techniques as possible therapeutic approach to suppress seizures.

UKÄ subject classification

  • Neurology

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