Research output per year
Research output per year
Medicon Village, Hus 404:B3 - Scheelevägen 2
22381 Lund
Sweden
Medicon Village, Hus 404:B3 - Scheelevägen 2
22381 Lund
Sweden
Future cancer care will use mutation analysis of tumour DNA as a tool to match each patient with the best possible treatment. To do this we must improve our understanding of the importance of different mutations. Today, analyses completely focus on mutations that are relatively easy to interpret, while so-called "silent" or synonymous mutations, which do not directly alter a protein, are filtered out. However, also synonymous mutations can be functional through effects on e.g. mRNA splicing or the speed of translation. We study synonymous mutations in breast cancers from several thousand Swedish women to investigate their effects on tumour behaviour with a combination of bioinformatic analyses and functional studies. Through this research we wish to demonstrate that also "silent" mutations are important so that more patients can receive targeted treatment. Hopefully, our work will also lead to identification of new therapeutical targets and a reevaluation of the standard analysis of sequencing data.
Person
Person
Person
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Thesis › Doctoral Thesis (compilation)
Persson, H. (PI)
2025/01/01 → 2028/12/31
Project: Research
Persson, H. (Researcher)
Märta Winklers stiftelse för främjande av medicinsk forskning
2024/11/01 → 2026/08/31
Project: Research
Müller, M. (Research student), Persson, H. (Supervisor), Bernardo, C. (Assistant supervisor), Kvist, A. (Assistant supervisor) & Axelson, H. (Assistant supervisor)
2023/07/03 → …
Project: Dissertation
Persson, H. (Member)
Activity: Consultancy, expert advice and memberships › Member of board/committee/council etc
Wittbom, C. (Organiser), Avery, H. (Organiser), Alkan Olsson, J. (Host), Nikoleris, L. (Host), Berntsson, P. (Host), Eksten, R. (Invited speaker), Mickwitz, P. (Invited speaker), Söderstjerna, E. (Contributor), Hansen, A. (Contributor), Persson, H. (Session chair) & Islar, M. (Session chair)
Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
Persson, H. (Member)
Activity: Consultancy, expert advice and memberships › Member of board/committee/council etc